Results 131 to 140 of about 4,680 (201)

Antibody-mediated depletion of human CLEC-2 in a novel humanized mouse model. [PDF]

Blood Adv, 2023
Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D.   +10 more
europepmc   +1 more source

Lymphatic endothelium in health and disease [PDF]

, 2018
The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal ...
Detmar, Michael, Jurisic, Giorgia
core  

Elevation of plasma podoplanin in Kawasaki disease

Journal of Laboratory Medicine
Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be ...
Xu Ling, Li Wei, Geng Zhimin, Peng Zhaoyang, Sun Anna, Qin Wenjun, Xie Chunhong, Gong Fangqi, Shen Hongqiang   +8 more
doaj   +1 more source

Podoplanin‐expressing inflammatory macrophages activate murine platelets via CLEC‐2 [PDF]

, 2011
A.M. KERRIGAN, Leyre Navarro‐Núñez, Elwira Pyż, Brenda Finney, Janet A. Willment, Steve P. Watson, G.D. BROWN   +6 more
openalex   +1 more source

Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice [PDF]

, 2013
Objective— Platelet inhibition is a major strategy to prevent acute ischemic cardiovascular and cerebrovascular events, which may, however, be associated with an increased bleeding risk.
Bender, M., Bosl, M., Braun, A., Finney, B. A., Hagedorn, I., Lorenz, V., May, F., Nieswandt, B., Remer, K., Thielmann, I., Vogtle, T., Watson, S. P.   +11 more
core   +1 more source

CLEC-2 Supports Platelet Aggregation in Mouse but not Human Blood at Arterial Shear. [PDF]

Thromb Haemost, 2022
Bourne JH, Smith CW, Jooss NJ, Di Y, Brown HC, Montague SJ, Thomas MR, Poulter NS, Rayes J, Watson SP.   +9 more
europepmc   +1 more source

An expanded role for semaphorin 4D in platelets includes contact‐dependent amplification of Clec‐2 signaling [PDF]

, 2013
Kenneth M. Wannemacher, Hong Jiang, Paul R. Hess, Yu‐Kyong Shin, Katsue Suzuki‐Inoue, Lawrence F. Brass   +5 more
openalex   +1 more source

Megakaryocytes produce a distinctive HSC niche through CLEC-2 guided secretion of TPO [PDF]

, 2013
Ayako Ishizu, Keiyo Takubo, Toshio Suda
openalex   +1 more source

Rol de las plaquetas en la inflamación [PDF]

, 2014
En condiciones fisiológicas, la activación de las plaquetas circulantes es limitada de manera constitutiva a través de la liberación, a partir del endotelio vascular, de potentes inhibidores de la función plaquetaria tales como el óxido nítrico y ...
Etulain, Julia, Schattner, Mirta Ana
core  

Cancellation of the Calcification in Cultured Osteoblasts by CLEC-2

Journal of Hard Tissue Biology, 2021
Takenori Kanai, Yoshiaki Sato, Yoshihiko Sawa   +2 more
openaire   +3 more sources