Results 131 to 140 of about 4,811 (202)

Avaliação dos níveis de podoplanina e CLEC-2 em pacientes diagnosticados com Covid-19

, 2022
Ivanio Teixeira de Borba
openalex   +1 more source

Podoplanin associates with CD44 to promote directional cell migration [PDF]

, 2010
This article is under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License.-- et al.Podoplanin is a transmembrane glycoprotein up-regulated in different human tumors, especially those derived from squamous stratified epithelia (
Fernández-Muñoz, Beatriz, Martín-Villar, Ester, Megías, Diego, Pérez-Gómez, Eduardo, Quintanilla, Miguel, Yurrita, María M.   +5 more
core   +2 more sources

Ocular Surface Reconstruction with Cultivated Limbal Epithelial Cells in Limbal Stem Cell Deficiency: One-year Follow-up Results

Türk Oftalmoloji Dergisi, 2012
Pur po se: To evaluate the 1-year follow-up results of cultivated limbal epithelial cell (CLEC) transplantation in unilateral limbal stem cell deficiency (LSCD).
İsmet Durak, Özlem Barut Selver, Esra Erdal, İmge Kunter, Zeynep Özbek Söylemezoğlu, Jose Mario Wolosin   +5 more
doaj   +1 more source

Podoplanin-positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion [PDF]

, 2014
Podoplanin (PDPN) is a well established lymphatic endothelial marker and has frequently been observed in cancer cells at the edge of cancer masses. Previous studies investigating the association between PDPN expression and patient prognosis have had ...
Ai, JY, Chen, K, Fu, L, Guan, X, Li, JC, Li, Y, Qin, YR, Wang, LJ, Zhu, YH   +8 more
core   +1 more source

Elevation of plasma podoplanin in Kawasaki disease

Journal of Laboratory Medicine
Kawasaki disease (KD) is a systemic vasculitis that results in abnormalities in the coronary arteries. Podoplanin (PDPN) and its receptor C-type lectin-like receptor 2 (CLEC-2) are involved in inflammatory hemostasis and have also been proved to be ...
Xu Ling, Li Wei, Geng Zhimin, Peng Zhaoyang, Sun Anna, Qin Wenjun, Xie Chunhong, Gong Fangqi, Shen Hongqiang   +8 more
doaj   +1 more source

Antibody-mediated depletion of human CLEC-2 in a novel humanized mouse model. [PDF]

Blood Adv, 2023
Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D.   +10 more
europepmc   +1 more source

Rol de las plaquetas en la inflamación [PDF]

, 2014
En condiciones fisiológicas, la activación de las plaquetas circulantes es limitada de manera constitutiva a través de la liberación, a partir del endotelio vascular, de potentes inhibidores de la función plaquetaria tales como el óxido nítrico y ...
Etulain, Julia, Schattner, Mirta Ana
core  

Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β [PDF]

, 2015
BACKGROUND: The C‐type lectin‐like receptor 2 (CLEC‐2) and the collagen receptor glycoprotein (GP)VI activate platelets through Src and Syk tyrosine kinases, and phospholipase Cγ2.
Moroi, A. J., Watson, S. P.
core   +1 more source

Platelets regulate lymphatic vascular development through CLEC-2–SLP-76 signaling

Blood, 2010
AbstractAlthough platelets appear by embryonic day 10.5 in the developing mouse, an embryonic role for these cells has not been identified. The SYK–SLP-76 signaling pathway is required in blood cells to regulate embryonic blood-lymphatic vascular separation, but the cell type and molecular mechanism underlying this regulatory pathway are not known.
Bertozzi, Cara C., Schmaier, Alec A., Mericko, Patricia, Hess, Paul R., Zou, Zhiying, Chen, Mei, Chen, Chiu-Yu, Xu, Bin, Lu, Min-min, Zhou, Diane, Sebzda, Eric, Santore, Matthew T., Merianos, Demetri J., Stadtfeld, Matthias, Flake, Alan W., Graf, Thomas, Skoda, Radek, Maltzman, Jonathan S., Koretzky, Gary A., Kahn, Mark L.   +19 more
openaire   +4 more sources

PB0397 Differential Requirement for Ligand Valency in the Activation of CLEC-2 in Human and Humanised Mouse Platelets

, 2023
Jane Clark, Eva Denise Martin, Lisa Moran, Di Yang, Hannah M. Brown, Bernhard Nieswandt, David Stegner, Ángel Galindo García, Steve P. Watson   +8 more
openalex   +1 more source