Results 121 to 130 of about 24,575,655 (169)

Role of platelet CLEC‐2 and podoplanin in inflammation and vascular integrity [PDF]

, 2017
Introduction: The platelet receptor CLEC‐2 is believed to play a key role in many of the newly emerging roles of platelets, such as development and inflammation. The aim of this thesis was to look further into the interaction of CLEC‐2 and podoplanin and
Lombard, Stephanie Eileen
core   +1 more source

Soluble CLEC-2 as an Emerging Biomarker of In Vivo Platelet Activation. [PDF]

J Clin Med
Suzuki-Inoue K, Ueda M, Shirai T, Tsukiji N, Sasaki T.   +4 more
europepmc   +1 more source

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP.

Blood, 2022
Shao B, Hoover C, Shi H, Kondo Y, Lee RH, Chen J, Shan X, Song J, McDaniel JM, Zhou M, McGee S, Vanhoorelbeke K, Bergmeier W, López JA, George JN, Xia L.   +15 more
europepmc   +1 more source

Platelet CLEC-2 activation leads to GPIb⍺ shedding: Implications for doxorubicin chemotherapy and thrombosis. [PDF]

J Biol Chem
Rousseau Z, Ma W, Long T, Slavkovic S, Qiu X, Lao X, Wu XG, Joshi K, Zhu YA, Zhu G, Thu KL, Ni H.   +11 more
europepmc   +1 more source

Receptor homodimerization significantly prolongs the lifetime of ligand-induced cross-linking of CLEC-2 but not GPVI. [PDF]

Blood Vessel Thromb Hemost
Clark JC, Martin EM, Slater A, Calebiro D, Koszegi Z, Watson SP.   +5 more
europepmc   +1 more source

The prognostic significance of CLEC-2-related gene signal in lung adenocarcinoma: A multicenter development and validation cohort. [PDF]

Clin Transl Med, 2020
Zhou C, Lei L, Ji MH, Yang JJ, Xia H.
europepmc   +1 more source

Decreased plasma level of C-type lectin-like receptor 2 (CLEC-2) in patients with breast cancer. [PDF]

Int J Med Sci
Chen CC, Hsuan CF, Yu TH, Hsu CC, Wu CC, Tang WH, Hung WC, Lu YC, Chung FM, Lee YJ, Wei CT.   +10 more
europepmc   +1 more source

Control of Platelet CLEC-2-Mediated Activation by Receptor Clustering and Tyrosine Kinase Signaling. [PDF]

Biophys J, 2020
Martyanov AA, Balabin FA, Dunster JL, Panteleev MA, Gibbins JM, Sveshnikova AN.   +5 more
europepmc   +1 more source

The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure. [PDF]

Nat Commun, 2020
Chauhan A, Sheriff L, Hussain MT, Webb GJ, Patten DA, Shepherd EL, Shaw R, Weston CJ, Haldar D, Bourke S, Bhandari R, Watson S, Adams DH, Watson SP, Lalor PF.   +14 more
europepmc   +1 more source

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice. [PDF]

Blood Adv
Smith CW, Campos J, Brown HC, Jooss NJ, Ivanova VS, Harbi M, Garcia-Quintanilla L, Jossi S, Perez-Toledo M, Rookes K, Brill A, Theodore LN, Owens T, LaStant J, Foulke MC, Mukai S, Francesco M, Storek M, Hicks A, Langrish C, Nunn PA, Cunningham AF, Chauhan A, Thomas MR, Watson SP, Nicolson PLR.   +25 more
europepmc   +1 more source