Results 191 to 200 of about 328,516 (352)

MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read‐Through Transcription, and Intragenic Contacts

open access: yesAdvanced Science, EarlyView.
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang   +5 more
wiley   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

open access: yesAdvanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang   +13 more
wiley   +1 more source

Click chemistry on azide-functionalized graphene oxide

open access: yesElectrochemistry Communications, 2019
Chemical functionalization of graphene oxide represents a major challenge in chemical engineering with the aim of both improving the properties of the material while generating versatile platforms with a broad range of applications.
Andreea Cernat   +7 more
doaj  

Microwave assisted "click" chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support. [PDF]

open access: green, 2006
Camille Bouillon   +8 more
openalex  

Facile synthesis of dendritic-linear-dendritic materials by click chemistry [PDF]

open access: green, 2009
Jae Wook Lee   +7 more
openalex   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao   +27 more
wiley   +1 more source

Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry

open access: hybrid, 2008
Julian A. Codelli   +3 more
openalex   +1 more source

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