Results 221 to 230 of about 1,290,910 (349)

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Development of a First-in-Class Click Chemistry-Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial. [PDF]

Clin Cancer Res
Srinivasan S, Yee NA, Alečković M, Zakharian M, Mahmoodi A, Wagner S, Nguyen TH, Chawla SP, Guminski AD, Mejía Oneto JM.   +9 more
europepmc   +1 more source

Photochemical Ligation of DNA Probe prepared in Click Chemistry

, 2009
Yoshinaga Yoshimura, T Matsuzaki, Kenzo Fujimoto   +2 more
openalex   +2 more sources

Surface functionalization of nanofibrillated cellulose using click-chemistry approach in aqueous media [PDF]

, 2011
Nikolaos Pahimanolis, Ulla Hippi, Leena‐Sisko Johansson, Tapio Saarinen, Nikolay Houbenov, Janne Ruokolainen, Jukka Seppälä   +6 more
openalex   +1 more source

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

A novel strategy for Escherichia coli detection in raw beef in combination with click chemistry. [PDF]

NPJ Sci Food
Alzahrani A.
europepmc   +1 more source

Strain-Promoted “Click” Chemistry for Terminal Labeling of DNA [PDF]

, 2011
Isaac Marks, Jun Sung Kang, Brady T. Jones, Kevin J. Landmark, A. J. Cleland, T. Andrew Taton   +5 more
openalex   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Click Chemistry for Well-Defined Graft Copolymers. [PDF]

Polymers (Basel)
Ali MF, Ochiai B.
europepmc   +1 more source

Biofunctional Silicon Nanoparticles by Means of Thiol‐Ene Click Chemistry [PDF]

, 2011
L. Ruizendaal, Sidharam P. Pujari, Veronique S. Gevaerts, Jos M. J. Paulusse, Han Zuilhof   +4 more
openalex   +1 more source