Results 41 to 50 of about 1,276,924 (370)
Nanoplasmonics tuned “click chemistry” [PDF]
Nanoplasmonics is a growing field of optical condensed matter science dedicated to optical phenomena at the nanoscale level in metal systems. Extensive research on noble metallic nanoparticles (NPs) has emerged within the last two decades due to their ability to keep the optical energy concentrated in the vicinity of NPs, in particular, the ability to ...
Tijunelyte, I.+6 more
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Application of “Click” Chemistry in Biomedical Hydrogels
Since “click” chemistry was first reported in 2001, it has remained a popular research topic in the field of chemistry due to its high yield without byproducts, fast reaction rate, simple reaction, and biocompatibility.
X. Li, Yuzhu Xiong
semanticscholar +1 more source
Click chemistry in the design of AIEgens for biosensing and bioimaging
The development of rapid, selective, and sensitive fluorescent sensors is essential for visualizing and quantifying biological molecules and processes in vitro, ex vitro, and in vivo, which is important for not only fundamental biological studies but the
Marie‐Claire Giel, Yuning Hong
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Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry [PDF]
Modern combinatorial chemistry is used to discover compounds with desired function by an alternative strategy, in which the biological target is directly involved in the choice of ligands assembled from a pool of smaller fragments. Herein, we present the
Anna Lucia Fallacara+11 more
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Organotitanium Click Chemistry
The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising new synthetic approaches discussed herein, for pharmacological and bio orthogonal applications.
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Triazolinediones as highly enabling synthetic tools [PDF]
Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn+5 more
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Click chemistry and drug delivery: A bird's-eye view
Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task.
Shameer M. Kondengadan+5 more
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Molecular Hybridization of Alkaloids Using 1,2,3-Triazole-Based Click Chemistry
Alkaloids found in multiple species, known as ‘driver species’, are more likely to be included in early-stage drug development due to their high biodiversity compared to rare alkaloids.
Devan Buchanan+3 more
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Click Chemistry in Peptide-Based Drug Design
Click chemistry is an efficient and chemoselective synthetic method for coupling molecular fragments under mild reaction conditions. Since the advent in 2001 of methods to improve stereochemical conservation, the click chemistry approach has been broadly
Irwin Chaiken, Rachna Aneja, Huiyuan Li
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WHO holding the hands of the scientific commune and trying to repurpose the drugs against the SARS-CoV-2. The robust scientific data has illustrated the probable mechanistic path of SARS-CoV-2 entry and action in damaging the cells.
Satyaki Chatterjee+4 more
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