Results 91 to 100 of about 2,673,237 (301)

Development of Mixed metal Metal-organic polyhedra networks, colloids, and MOFs and their Pharmacokinetic applications

open access: yesScientific Reports, 2017
Summary The coordination networking of discrete metal-organic polyhedra (MOPs) involving different ligands as well as metals is a challenging task due to the features of limited solubility and chemical stability of these polyhedra.
Nazir Ahmad   +6 more
doaj   +1 more source

Advancements and applications of click chemistry in protein labeling and bioconjugation [PDF]

open access: yesRSC Advances
Click chemistry has emerged as a versatile and efficient chemical strategy for constructing complex molecules under mild conditions. Its core reaction is copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC), which provides high yields ...
Usman Nazeer, Guoting Qin, Chengzhi Cai
doaj   +1 more source

Synthesis and application of some novel functional polymers via controlled radical polymerization and click chemistry [PDF]

open access: yes
The objective of this thesis was to prepare thermoresponsive PEG-based homopolymers and copolymers by combination of cobalt-mediated catalytic chain-transfer polymerization (CCTP) and thiol-ene “click” chemistry and prepare well-defined glycopolymers ...
Li, Guang-Zhao
core  

Interview with Deb Click [PDF]

open access: yes, 1999
Deb Click, a Baptist pastor, describes her expirience of being ousted by the Lutheran Church, the support from her congregation and her decision not to fight the judgement.
Hitchcock, Kate, Click, Deb
core  

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Mechano-Induced Synthesis of Polyethylene Glycols α,ω-DiSubstituted with 4-(PAH)-1H-1,2,3-Triazoles in Presence of In Situ-Generated Bronze Microparticles as Catalyst

open access: yesMolecules
A method for the mechanochemical CuAAC click reaction (Cu+-promoted azido–alkyne cycloaddition) in the presence of bronze powder/copper beads without the use of a pre-introduced catalyst and ligands with greener prospect is presented. A new type of tri-,
Mohammed S. Mohammed   +6 more
doaj   +1 more source

Click Chemistry in Peptide-Based Drug Design

open access: yesMolecules, 2013
Click chemistry is an efficient and chemoselective synthetic method for coupling molecular fragments under mild reaction conditions. Since the advent in 2001 of methods to improve stereochemical conservation, the click chemistry approach has been broadly
Irwin Chaiken, Rachna Aneja, Huiyuan Li
doaj   +1 more source

One-pot click synthesis of hybrid triazole–pyridine-functionalized polyphenol derivatives under ultrasound irradiation and their antimicrobial assays

open access: yesScientific Reports
In the present work, we describe an efficient, straightforward, and environmentally friendly method for synthesizing hybrid triazole-pyridine-functionalized polyphenol derivatives via a one-pot, three-component click reaction under ultrasound irradiation.
Dorina Amariucai-Mantu   +4 more
doaj   +1 more source

Click reaction-induced in situ nanoparticle aggregation for cancer imaging and treatment

open access: yesEngMedicine
With their high drug-loading capacity and enhanced permeability and retention (EPR) effects, nanoparticles possess significant potential for the diagnosis and treatment of tumors.
Yun Yin   +3 more
doaj   +1 more source

Organobase-Catalyzed Hydroxyl-yne Click Polymerization [PDF]

open access: yes, 2019
The proposition of click chemistry has provided a quick channel for saccharides modification, which has always been worth exploring. Click reaction of hydroxyl groups possessed by saccharides is thus highly desirable to be developed.
Ben Zhong, Tang   +4 more
core   +2 more sources

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