Results 51 to 60 of about 1,905,942 (404)

Management of Aphthous Ulceration with Topical Quercetin: A Randomized Clinical Trial [PDF]

The Journal of Contemporary Dental Practice, 2010
Abstract Aim Recurrent aphthous ulceration is the most commonly known oral mucosal disease. Quercetin is a useful therapeutic agent for the treatment of colitis and gastric ulcer. The objective of this study was to determine the effect of topical application of quercetin in the treatment of minor aphthous ulcers.
Mohamed Abd El-Moneam Ibrahem, Ahmed Abd El-Meguid Mostafa Hamdy   +1 more
openaire   +2 more sources

Knowledge and Attitudes Towards Clinical Trial Participation in Oman: A cross-sectional study

Sultan Qaboos University Medical Journal, 2018
Objectives: Clinical trials are prospective studies on human subjects designed to answer various clinical questions. However, only a limited number of clinical trials have been conducted in Oman.
Hussain Al-Lawati, Khalid Al-Baimani, Mahra Al-Zadjali, Nasra Al-Obaidani, Ziyana Al-Kiyumi, Murtadha K. Al-Khabori   +5 more
doaj   +1 more source

Clinical Trials in Portugal: Past and Future. Position Paper from the Colleges of Clinical Pharmacology and Pharmaceutical Medicine

Acta Médica Portuguesa
N/a.
Filipa Borges-Carneiro, Miguel Torre Souto, Isabel Silva, Paula Leão Moreira, Paula Ferraz de Oliveira, Diogo José Lopes, Luís Figueira, Marta Reina-Couto, Luís Cunha-Miranda, Diogo Ponces Bento, Fernando Magro   +10 more
doaj   +1 more source

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Bailey, Matthew, Hackett, Maree, Hankey, Graeme J, Kutlubaev, Mansur A, Lee, Rebecca, Mead, Gillian E   +5 more
core   +1 more source

How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis [PDF]

, 2020
Introduction Adaptive designs offer a flexible approach, allowing changes to a trial based on examinations of the data as it progresses. Adaptive clinical trials are becoming a popular choice, as the prudent use of finite research budgets and accurate ...
Brennan, Alan, Flight, Laura, Hind, Daniel, Julious, Steven, Todd, Susan Todd   +4 more
core   +2 more sources

Novel trial designs: Master protocol trials

Perspectives in Clinical Research
Conventional trial designs are resource and time-intensive. To accelerate the process of testing new interventions, we now have several novel research trial designs.
Priya Ranganathan, Vishal Deo, C. S. Pramesh, Mahesh P. Parmar   +3 more
doaj   +1 more source

Asking new questions with old data: The Centralized Open-Access Rehabilitation database for Stroke (SCOAR).

Frontiers in Neurology, 2016
Background: This paper introduces a tool for streamlining data integration in rehabilitation science, the Centralized Open-Access Rehabilitation database for Stroke (SCOAR), which allows researchers to quickly visualize relationships among variables ...
Keith Lohse, Sydney Y Schaefer, Sydney Y Schaefer, Adam Raikes, Lara Boyd, Catherine E Lang   +5 more
doaj   +1 more source

Limits to the Evaluation of the Accuracy of Continuous Glucose Monitoring Systems by Clinical Trials

Biosensors, 2018
Systems for continuous glucose monitoring (CGM) are evolving quickly, and the data obtained are expected to become the basis for clinical decisions for many patients with diabetes in the near future.
P. Schrangl, F. Reiterer, L. Heinemann, G. Freckmann, L. del Re   +4 more
semanticscholar   +1 more source

Everolimus as first line therapy for pancreatic neuroendocrine tumours: current knowledge and future perspectives [PDF]

, 2017
urpose Everolimus has been shown to be effective for advanced pancreatic neuroendocrine tumours (pNETs), but its positioning in the therapeutic algorithm for pNETs is matter of debate.
Badalamenti, G., Colao, A., Faggiano, A., Fanciulli, G., Gallo, M., Giordano, C., Malandrino, P., Rota, F.   +7 more
core   +1 more source

Barriers and facilitators to healthcare professional behaviour change in clinical trials using the Theoretical Domains Framework: a case study of a trial of individualized temperature-reduced haemodialysis

Trials, 2017
BackgroundImplementing the treatment arm of a clinical trial often requires changes to healthcare practices. Barriers to such changes may undermine the delivery of the treatment making it more likely that the trial will demonstrate no treatment effect ...
J. Presseau, Brittany Mutsaers, Ahmed A. Al-Jaishi, J. Squires, C. McIntyre, A. Garg, M. Sood, J. Grimshaw   +7 more
semanticscholar   +1 more source