Results 51 to 60 of about 612,154 (364)

Topical isoniazid as a novel treatment for melasma: A randomized, double‐blind, vehicle‐controlled clinical trial

Journal of Cosmetic Dermatology
AbstractIntroductionMelasma is a chronic hyperpigmentation disorder, and its treatment poses a challenge to dermatologists due to its chronicity and resistance to conventional therapies. Oral isoniazid is used for the treatment of tuberculosis. One of us had previously showed that topical isoniazid exerts a strong depigmenting action in animal models ...
Najmeh, Ahramiyanpour, Zahra, Mahmoudi, Nazanin Zeinali, Nezhad, Payam, Khazaeli, Rezvan, Amiri, Behrooz, Kasraee   +5 more
openaire   +2 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Structured review of the patient-reported outcome instruments used in clinical trials in head and neck surgery [PDF]

, 2018
The number of clinical trials that relate to patients with cancer of the head and neck is growing. Patient-reported outcomes, which are rarely the primary outcome, are now an important component, and in this structured review to identify and report the ...
Barraclough, J, Boyes, H, Kanatas, A, Ratansi, R, Rogers, SN   +4 more
core   +2 more sources

Effectiveness of photodynamic therapy as an adjunct to topical antiviral therapy in the treatment of herpes labialis: A randomized controlled clinical trial

Photodiagnosis and Photodynamic Therapy, 2021
The present clinical trial assessed the effectiveness of photodynamic therapy in association with topical acyclovir in the treatment of herpes labialis in adolescent patients.45 individuals with herpes labialis were divided into three groups on the basis of provision of treatment.
openaire   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

A shared latent space matrix factorisation method for recommending new trial evidence for systematic review updates

, 2018
Clinical trial registries can be used to monitor the production of trial evidence and signal when systematic reviews become out of date. However, this use has been limited to date due to the extensive manual review required to search for and screen ...
Bashir, Rabia, Bourgeois, Florence T., Coiera, Enrico, Dunn, Adam G., Orenstein, Liat, Surian, Didi   +5 more
core   +1 more source

Clinical Assessment of Topical Methotrexate Micro-emulsion as a Treatment for Psoriasis: A Randomized Clinical Trial

Hormozgan Medical Journal
Objectives: Psoriasis is an inflammatory skin disease, and the main topical treatment for this disease is corticosteroids, vitamin D analogs, salicylic acid, and calcineurin inhibitors. This study clinically evaluates a topical dosage form of methotrexate (MTX) micro-emulsion and compares it with clobetasol lotion.
Mohammad Sadegh Sayyafan, Farhad Handjani, Shoeib Sharifi, Maryam Sadat Sadati, Zahra Hashempour   +4 more
openaire   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Evaluation of sodium nitroprusside for controlled hypotension in children during surgery

Frontiers in Pharmacology, 2015
Purpose. (1) To define the onset and offset of the blood-pressure-lowering effects of sodium nitroprusside (SNP) for use in developing instructions for dose titration in children undergoing a surgical or medical procedure, and (2) to assess the safety of
David R Drover, Gregory B Hammer, Jeffrey Scott Barrett, Carol A Cohane, Tammy eReece, Anne eZajicek, Scott eSchulman, Scott eSchulman   +7 more
doaj   +1 more source

Calcific uraemic arteriolopathy - A mini-review [PDF]

, 2016
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica, Fragoso, Andr?, Jerónimo, Teresa, Mendes, Filipa, Neves, Pedro L, Pimentel, Ana, Rocha, Sofia Couto, Silva, Ana   +7 more
core