Results 51 to 60 of about 1,939,729 (406)

Artificial Intelligence for In Silico Clinical Trials: A Review [PDF]

arXiv, 2022
A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials. AI-enabled in silico trials can increase the case group size by creating virtual cohorts as controls. In addition,
arxiv  

Reproducibility of ambulatory blood pressure changes from the initial values on two different days

Clinics, 2013
OBJECTIVE: We tested the reproducibility of changes in the ambulatory blood pressure (BP) from the initial values, an indicator of BP reactivity and cardiovascular health outcomes, in young, healthy adults.
Garrett I. Ash, Timothy J. Walker, Kayla M. Olson, Jeffrey H. Stratton, Ana L. Gomez, William J. Kraemer, Jeff S. Volek, Linda S. Pescatello   +7 more
doaj   +1 more source

Asking new questions with old data: The Centralized Open-Access Rehabilitation database for Stroke (SCOAR).

Frontiers in Neurology, 2016
Background: This paper introduces a tool for streamlining data integration in rehabilitation science, the Centralized Open-Access Rehabilitation database for Stroke (SCOAR), which allows researchers to quickly visualize relationships among variables ...
Keith Lohse, Sydney Y Schaefer, Sydney Y Schaefer, Adam Raikes, Lara Boyd, Catherine E Lang   +5 more
doaj   +1 more source

Clinical Trials in Portugal: Past and Future. Position Paper from the Colleges of Clinical Pharmacology and Pharmaceutical Medicine

Acta Médica Portuguesa
N/a.
Filipa Borges-Carneiro, Miguel Torre Souto, Isabel Silva, Paula Leão Moreira, Paula Ferraz de Oliveira, Diogo José Lopes, Luís Figueira, Marta Reina-Couto, Luís Cunha-Miranda, Diogo Ponces Bento, Fernando Magro   +10 more
doaj   +1 more source

Pulmonary Hypertension Association's 2022 International Conference Scientific Sessions Overview

Pulmonary Circulation, 2023
The considerable progress made in recent years in the diagnosis, risk stratification, and treatment of pulmonary hypertension was highlighted during the most recent edition of the Pulmonary Hypertension Association Scientific Sessions, which was held in ...
Ayedh K. Alamri, Nicholas J. Shelburne, Jennalyn D. Mayeux, Evan Brittain   +3 more
doaj   +1 more source

Knowledge and Attitudes Towards Clinical Trial Participation in Oman: A cross-sectional study

Sultan Qaboos University Medical Journal, 2018
Objectives: Clinical trials are prospective studies on human subjects designed to answer various clinical questions. However, only a limited number of clinical trials have been conducted in Oman.
Hussain Al-Lawati, Khalid Al-Baimani, Mahra Al-Zadjali, Nasra Al-Obaidani, Ziyana Al-Kiyumi, Murtadha K. Al-Khabori   +5 more
doaj   +1 more source

Interventions for treating anxiety after stroke [PDF]

, 2011
Background: Approximately 20% of stroke patients experience anxiety at some point after stroke. Objectives: To determine if any treatment for anxiety after stroke decreases the proportion of patients with anxiety disorders or symptoms, and to ...
Ahlsiö, Astrom, Baldwin, Beck, Beck, Beck, Boeijen, Burvill, Campbell Burton, Castillo, Craig, DerSimonian, Gelder, Givens, Hackett, Hackett, Hamilton, Hamilton, Hatano, Higgins, House, Hyde, Jorm, Kimura, Langhorne, Lepine, Li, Lincoln, Liu, Mahoney, Max, Mok, Montgomery, Morrison, Riedel-Heller, Rijswijk, Rorsman, Sharpe, Shimoda, Wade, Wang, Ware, Wittchen, Wu, Ye, Zarit, Zhang   +46 more
core   +1 more source

Novel trial designs: Master protocol trials

Perspectives in Clinical Research
Conventional trial designs are resource and time-intensive. To accelerate the process of testing new interventions, we now have several novel research trial designs.
Priya Ranganathan, Vishal Deo, C. S. Pramesh, Mahesh P. Parmar   +3 more
doaj   +1 more source

Limits to the Evaluation of the Accuracy of Continuous Glucose Monitoring Systems by Clinical Trials

Biosensors, 2018
Systems for continuous glucose monitoring (CGM) are evolving quickly, and the data obtained are expected to become the basis for clinical decisions for many patients with diabetes in the near future.
P. Schrangl, F. Reiterer, L. Heinemann, G. Freckmann, L. del Re   +4 more
semanticscholar   +1 more source

Barriers and facilitators to healthcare professional behaviour change in clinical trials using the Theoretical Domains Framework: a case study of a trial of individualized temperature-reduced haemodialysis

Trials, 2017
BackgroundImplementing the treatment arm of a clinical trial often requires changes to healthcare practices. Barriers to such changes may undermine the delivery of the treatment making it more likely that the trial will demonstrate no treatment effect ...
J. Presseau, Brittany Mutsaers, Ahmed A. Al-Jaishi, J. Squires, C. McIntyre, A. Garg, M. Sood, J. Grimshaw   +7 more
semanticscholar   +1 more source