Results 61 to 70 of about 635,069 (409)

Optimal search strategies for identifying sound clinical prediction studies in EMBASE [PDF]

, 2005
BACKGROUND: Clinical prediction guides assist clinicians by pointing to specific elements of the patient's clinical presentation that should be considered when forming a diagnosis, prognosis or judgment regarding treatment outcome.
A Laupacis, AG Randolph, AR Jadad, BJ Ingui, BT Walsh, CE Adams, FA McAlister, Jennifer L Holland, JF Steiner, JH Wasson, JI Emparanza, JW Ely, LM Bachmann, LM Bachmann, Nancy L Wilczynski, NL Wilczynski, NL Wilczynski, NL Wilczynski, PS Wells, R Brian Haynes, RB Haynes, RB Haynes, RJ Watson, SS Wong, T McGinn, TG McGinn   +25 more
core   +3 more sources

Exosomes and Immune Response in Cancer: Friends or Foes?

Frontiers in Immunology, 2018
Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent years. This led to the understanding that these structures, far from being inert waste by-products of cellular functioning, are active players in intercellular ...
Francisco M. Barros, Fatima Carneiro, Fatima Carneiro, Fatima Carneiro, Fatima Carneiro, Jose C. Machado, Jose C. Machado, Jose C. Machado, Sónia A. Melo, Sónia A. Melo, Sónia A. Melo   +10 more
doaj   +1 more source

“It’s trying to manage the work” : A qualitative evaluation of recruitment processes within a UK multi-centre trial [PDF]

, 2017
Acknowledgments The authors would like to thank all interviewees who agreed to take part in this study. The authors would like to thank the TISU Trial Group for their support with this project. In particular, the authors would like to thank Sarah Cameron
Gillies, Katie, Skea, Zoe Christina, Treweek, Shaun   +2 more
core   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Targeting mTOR in Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2016
Treatment options for advanced pancreatic ductal adenocarcinoma (PDAC) are limited, however, new therapies targeting specific tumor-related molecular characteristics may help certain patient cohorts. Emerging preclinical data has shown that inhibition of
Sentia eIriana, Shahzad eAhmed, Jun eGong, Jun eGong, Alagappan Anand Annamalai, Richard eTuli, Andrew Eugene Hendifar   +6 more
doaj   +1 more source

Topical isoniazid as a novel treatment for melasma: A randomized, double‐blind, vehicle‐controlled clinical trial

Journal of Cosmetic Dermatology
AbstractIntroductionMelasma is a chronic hyperpigmentation disorder, and its treatment poses a challenge to dermatologists due to its chronicity and resistance to conventional therapies. Oral isoniazid is used for the treatment of tuberculosis. One of us had previously showed that topical isoniazid exerts a strong depigmenting action in animal models ...
Najmeh, Ahramiyanpour, Zahra, Mahmoudi, Nazanin Zeinali, Nezhad, Payam, Khazaeli, Rezvan, Amiri, Behrooz, Kasraee   +5 more
openaire   +2 more sources

Anticoagulants for acute ischaemic stroke [PDF]

, 2015
Peer reviewedPublisher ...
Counsell, Carl, Kane, Edward J, Sandercock, Peter A G   +2 more
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Effectiveness of photodynamic therapy as an adjunct to topical antiviral therapy in the treatment of herpes labialis: A randomized controlled clinical trial

Photodiagnosis and Photodynamic Therapy, 2021
The present clinical trial assessed the effectiveness of photodynamic therapy in association with topical acyclovir in the treatment of herpes labialis in adolescent patients.45 individuals with herpes labialis were divided into three groups on the basis of provision of treatment.
openaire   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source