Results 61 to 70 of about 608,159 (405)
Inadequate reporting quality of registered genome editing trials: an observational study
BMC Medical Research Methodology, 2022 Background To assess registration completeness and safety data of trials on human genome editing (HGE) reported in primary registries and published in journals, as HGE has safety and ethical problems, including the risk of undesirable and unpredictable ...
Diana Jurić +2 more
doaj +1 more source
Drug Design, Development and Therapy, 2015 Treatment of melasma is unsatisfactory most of the times. Hormonal role is shown to exist in pathogenesis of the melasma, and sex-hormone related drugs may have an effect on melasma.To investigate efficacy of 1% flutamide cream versus 4% hydroquinone cream on melasma.In a parallel randomized clinical trial, 74 women with melasma were allocated to ...
Hassan Adalatkhah +1 more
openaire +6 more sources
Protecting patient privacy when sharing patient-level data from clinical trials
BMC Medical Research Methodology, 2016 BackgroundGreater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as
K. Tucker +6 more
semanticscholar +1 more source
Video assisted thoracic surgery for treatment of pneumothorax and lung resections: systematic review of randomised clinical trials [PDF]
, 2004 <b>Objectives</b> To determine if video assisted thoracic surgery is associated with better clinical outcomes than thoracotomy for three common procedures: surgery for pneumothorax, minor resections, and lobectomy.
Lewsey, J. +3 more
core +3 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Exosomes and Immune Response in Cancer: Friends or Foes?
Frontiers in Immunology, 2018 Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent years. This led to the understanding that these structures, far from being inert waste by-products of cellular functioning, are active players in intercellular ...
Francisco M. Barros +10 more
doaj +1 more source
An alternative approach to deal with the absence of clinical trials: a proportional meta-analysis of case series studies [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: Systematic reviews are criticized for frequently offering inconsistent evidences and absence of straightforward recommendations. Their value seems to be depreciated when the conclusions are uncertain.
Regina El Dib +2 more
doaj +2 more sources
Double-blind clinical trial of topical steroids in anterior uveitis. [PDF]
British Journal of Ophthalmology, 1979 We present the results of a double-blind trial comparing the efficacy of betamethasone phosphate 0.1%, clobetasone butyrate 0.1%, and placebo in the treatment of acute unilateral nongranulomatous uveitis. The 2 steroids were equally comparable in improvement of the patients' symptoms, though betamethasone phosphate was significantly more effective than
J A Dunne, J P Travers
openaire +3 more sources
Choosing and using methodological search filters : searchers' views [PDF]
, 2015 © 2014 The authors.
Beale, Sophie +10 more
core +1 more source