Results 91 to 100 of about 125,163 (295)

Circadian oscillator proteins across the kingdoms of life: structural aspects

BMC Biology, 2019
Circadian oscillators are networks of biochemical feedback loops that generate 24-hour rhythms in organisms from bacteria to animals. These periodic rhythms result from a complex interplay among clock components that are specific to the organism, but ...
Reena Saini, Mariusz Jaskolski, Seth J. Davis   +2 more
doaj   +1 more source

No Evidence That Homologs of Key Circadian Clock Genes Direct Circadian Programs of Development or mRNA Abundance in Verticillium dahliae

Frontiers in Microbiology, 2020
Many organisms harbor circadian clocks that promote their adaptation to the rhythmic environment. While a broad knowledge of the molecular mechanism of circadian clocks has been gained through the fungal model Neurospora crassa, little is known about ...
Emma Cascant-Lopez, Susan K. Crosthwaite, Louise J. Johnson, Richard J. Harrison, Richard J. Harrison   +4 more
doaj   +1 more source

New insights into the mechanisms of phytochrome-cryptochrome coaction. [PDF]

, 2018
Contents Summary 547 I. Introduction 547 II. Phytochromes mediate light-induced transcription of BICs to inactivate cryptochromes 548 III. PPKs phosphorylate light-signaling proteins and histones to affect plant development 548 IV.
Ahmad, Bourbousse, Bourbousse, Casas-Mollano, Cashmore, Devlin, Guo, Hoecker, Huang, Hughes, Huq, Ichikawa, Jang, Leivar, Lian, Liu, Liu, Liu, Lu, Ma, Martinez-Garcia, Mas, Mohr, Ni, Ni, Ni, Nusinow, Pedmale, Quail, Rosenfeldt, Saijo, Sang, Sellaro, Shalitin, Sheerin, Su, Su, Tessadori, Tessadori, Wang, Wang, Wang, Wang, Wang, Weidler, Yang, Zheng, Zuo   +47 more
core   +1 more source

Circadian control of interferon-sensitive gene expression in murine skin. [PDF]

, 2020
The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi, Dragan, Morgan, Greenberg, Elyse Noelani, Gudjonsson, Johann E, Jin, Suoqin, Marshall, Michaela Ellen, Nie, Qing, Takahashi, Joseph S, Tsoi, Lam C, Venkatesh, Sanan   +9 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Real-Time In Vitro Fluorescence Anisotropy of the Cyanobacterial Circadian Clock

Methods and Protocols, 2019
Uniquely, the circadian clock of cyanobacteria can be reconstructed outside the complex milieu of live cells, greatly simplifying the investigation of a functioning biological chronometer. The core oscillator component is composed of only three proteins,
Joel Heisler, Archana Chavan, Yong-Gang Chang, Andy LiWang   +3 more
doaj   +1 more source

Intricate Protein-Protein Interactions in the Cyanobacterial Circadian Clock [PDF]

Journal of Biological Chemistry, 2014
The cyanobacterial circadian clock consists of a post-translational oscillator (PTO) and a PTO-dependent transcription-translation feedback loop (TTFL). The PTO can be reconstituted in vitro with the KaiA, KaiB, and KaiC proteins, enabling detailed biochemical and biophysical investigations.
openaire   +2 more sources

A Variable Polyglutamine Repeat Affects Subcellular Localization and Regulatory Activity of a Populus ANGUSTIFOLIA Protein. [PDF]

, 2018
Polyglutamine (polyQ) stretches have been reported to occur in proteins across many organisms including animals, fungi and plants. Expansion of these repeats has attracted much attention due their associations with numerous human diseases including ...
Barry, Kerrie, Bryan, Anthony C, Chen, Jin-Gui, Guo, Jianjun, Jacobson, Daniel, Jawdy, Sara, Muchero, Wellington, Ranjan, Priya, Schmutz, Jeremy, Singan, Vasanth, Tuskan, Gerald A, Weighill, Deborah, Zhang, Jin   +12 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers [PDF]

, 2009
Interpretations of molecular data by the modern evolution theory are often sharply inconsistent with paleontological results. This is to be expected since the theory is only true for microevolution and yet fossil records are mostly about macroevolution.
Shi Huang
core   +1 more source