Results 291 to 300 of about 5,752,696 (345)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock. [PDF]

Cell Mol Life Sci
Chen W, Zhang H, Guo B, Tao Y, Zhang J, Wang J, Chen G, Cheng M, Hong Q, Cao Y, Xie F.   +10 more
europepmc   +1 more source

Combining lineage correlations and a small molecule inhibitor to detect circadian control of the cell cycle. [PDF]

iScience
Nikhat A, Shaikh A, Chakrabarti S.
europepmc   +1 more source

Transcription of Clock Genes in Medulloblastoma. [PDF]

Cancers (Basel)
Vriend J, Glogowska A.
europepmc   +1 more source

Anti-Müllerian hormone signalling sustains circadian homeostasis in zebrafish. [PDF]

Nat Commun
Lin Q, Du X, Ren F, Liu Y, Gong G, Ge S, Li W, Li Z, Zhou L, Duan M, Li XY, Wang GZ, Xiao R, Gui JF, Mei J.   +14 more
europepmc   +1 more source

Circadian clock gene expression: a key player in inflammation underlying chronic lung disease? [PDF]

ERJ Open Res
Makrinioti H, Chun S.
europepmc   +1 more source

The metabolic significance of peripheral tissue clocks. [PDF]

Commun Biol
Hunter AL, Bechtold DA.
europepmc   +1 more source

RETRACTION: lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway

Molecular Oncology, EarlyView.
RETRACTION: W. Pan, W. Li, J. Zhao, Z. Huang, J. Zhao, S. Chen, C. Wang, Y. Xue, F. Huang, Q. Fang, J. Wang, D. Brand, and S. G. Zheng, “lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway,” Molecular Oncology 13, no. 10 (2019): 2246–2258, https://doi.org/10.1002/1878-0261.12553.
wiley   +1 more source

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The diversity and evolution of circadian clock proteins in fungi

Mycologia, 2010
Circadian rhythms are endogenous cellular patterns that associate multiple physiological and molecular functions with time. The Neurospora circadian system contains at least three oscillators: the FRQ/WC-dependent circadian oscillator (FWO), whose core components are the FRQ, WC-1, WC-2, FRH, and FWD-1 proteins; the WC-dependent circadian oscillator ...
Leonidas Salichos, Antonis Rokas
openaire   +4 more sources