Results 31 to 40 of about 5,752,696 (345)

Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors

Tumor Biology, 2012
The majority of our genes may be regulated in a daily rhythm, including the genes for cell cycle control. Epidemiological and genetic evidences suggest that disruption of circadian timing mechanisms makes our cells more vulnerable to cancer formation.
Zsuzsanna Lengyel, György Szekeres, Zita Battyáni, Rita Keszthelyi, Valér Csernus, Csenge Lovig, András D. Nagy, Siri Kommedal   +7 more
openaire   +4 more sources

Nucleocytoplasmic Shuttling of Clock Proteins

Methods in Enzymology, 2005
The mammalian circadian clock in the neurons of suprachiasmatic nuclei (SCN) in the brain and in cells of peripheral tissues is driven by a self-sustained molecular oscillator, which generates rhythmic gene expression with a periodicity of about 24?h (Reppert and Weaver, 2002).
Gijsbertus T. J. van der Horst, Kazuhiro Yagita, Filippo Tamanini, Hitoshi Okamura   +3 more
openaire   +5 more sources

When lowering temperature, the in vivo circadian clock in cyanobacteria follows and surpasses the in vitro protein clock trough the Hopf bifurcation. [PDF]

Sci Rep
The in vivo circadian clock in single cyanobacteria is studied here by time-lapse fluorescence microscopy when the temperature is lowered below 25{\deg}C . We first disentangle the circadian clock behavior from the bacterial cold shock response by identifying a sequence of "death steps" based on cellular indicators. By analyzing only "alive" tracks, we
Mihalcescu I, Kaji H, Maruyama H, Giraud J, Van Melle-Gateau M, Houchmandzadeh B, Ito H.   +6 more
europepmc   +2 more sources

Mass spectrometry-based absolute quantification reveals rhythmic variation of mouse circadian clock proteins. [PDF]

Proc Natl Acad Sci U S A, 2016
Narumi R, Shimizu Y, Ukai-Tadenuma M, Ode KL, Kanda GN, Shinohara Y, Sato A, Matsumoto K, Ueda HR.   +8 more
europepmc   +2 more sources

Non-cyclic and Developmental Stage-Specific Expression of Circadian Clock Proteins During Murine Spermatogenesis1 [PDF]

Biology of Reproduction, 2003
John Alvarez, Dechun Chen, E Storer, Amita Sehgal   +3 more
openalex   +2 more sources

Anabaena circadian clock proteins KaiA and KaiB reveal a potential common binding site to their partner KaiC [PDF]

EMBO Journal, 2004
Robert Garces, Ning Wu, W. Gillon, E.F. Pai   +3 more
openalex   +2 more sources

The two clock proteins CCA1 and LHY activate VIN3 transcription during vernalization through the vernalization-responsive cis-element.

The Plant Cell, 2021
Vernalization, a long-term cold-mediated acquisition of flowering competence, is critically regulated by VERNALIZATION INSENSITIVE 3 (VIN3), a gene induced by vernalization in Arabidopsis.
Jinseul Kyung, Myeongjune Jeon, Goowon Jeong, Y. Shin, Eunjoo Seo, Jihyeon Yu, Hoyeun Kim, Chung-Mo Park, D. Hwang, Ilha Lee   +9 more
semanticscholar   +1 more source

Investigations of the CLOCK and BMAL1 Proteins Binding to DNA: A Molecular Dynamics Simulation Study. [PDF]

PLoS ONE, 2016
The circadian locomotor output cycles kaput (CLOCK), and brain and muscle ARNT-like 1 (BMAL1) proteins are important transcriptional factors of the endogenous circadian clock.
Tuo Xue, Chunnian Song, Qing Wang, Yan Wang, Guangju Chen   +4 more
doaj   +1 more source

The Essential and the Nonessential Roles of Four Clock Elements in the Circadian Rhythm of Metarhiziumrobertsii

Journal of Fungi, 2022
FRQ (frequency protein), FRH (FRQ-interacting RNA helicase), and WC1 and WC2 (white collar proteins) are major clock elements that govern the circadian rhythm in Neurosporacrassa. However, deletion of frh is lethal for the viability of N.
Han Peng, Yi-Lu Zhang, Sheng-Hua Ying, Ming-Guang Feng   +3 more
doaj   +1 more source

Supply of methionine and arginine alters phosphorylation of mechanistic target of rapamycin (mTOR), circadian clock proteins, and α-s1-casein abundance in bovine mammary epithelial cells.

Food & Function, 2020
Methionine (Met) and arginine (Arg) regulate casein protein abundance through alterations in activity of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway.
Liangyu Hu, Yifei Chen, Ismael M Cortes, D. Coleman, H. Dai, Yusheng Liang, C. Parys, C. Fernández, Mengzhi Wang, J. Loor   +9 more
semanticscholar   +1 more source