Results 41 to 50 of about 127,418 (322)

Expression of clock proteins in developing tooth [PDF]

Gene Expression Patterns, 2011
Morphological and functional changes during ameloblast and odontoblast differentiation suggest that enamel and dentin formation is under circadian control. Circadian rhythms are endogenous self-sustained oscillations with periods of 24h that control diverse physiological and metabolic processes.
Li, Zheng, Silvana, Papagerakis, Santiago D, Schnell, Willemijntje A, Hoogerwerf, Petros, Papagerakis   +4 more
openaire   +2 more sources

Proteome analysis of the circadian clock protein PERIOD2

Proteins: Structure, Function, and Bioinformatics, 2022
AbstractCircadian rhythms are a series of endogenous autonomous 24‐h oscillations generated by the circadian clock. At the molecular level, the circadian clock is based on a transcription–translation feedback loop, in which BMAL1 and CLOCK transcription factors of the positive arm activate the expression of CRYPTOCHROME (CRY) and PERIOD (PER) genes of ...
Huseyin Gul, Saba Selvi, Fatma Yilmaz, Gozde Ozcelik, Senanur Olfaz‐Aslan, Seyma Yazan, Busra Tiryaki, Seref Gul, Ali Yurtseven, Ibrahim Halil Kavakli, Nurhan Ozlu, Nuri Ozturk   +11 more
openaire   +3 more sources

Mutation of Arabidopsis SPLICEOSOMAL TIMEKEEPER LOCUS1 Causes Circadian Clock Defects [PDF]

, 2012
The circadian clock plays a crucial role in coordinating plant metabolic and physiological functions with predictable environmental variables, such as dusk and dawn, while also modulating responses to biotic and abiotic challenges.
Brown, John WS, Harmer, Stacey L, Jones, Matthew A, McNicol, Jim, Simpson, Craig G, Williams, Brian A   +5 more
core   +1 more source

Clock proteins: Turned over after hours? [PDF]

Current Biology, 2000
Light sensitivity and the involvement of unstable proteins are key features of circadian clocks. Both photoreception and ubiquitin conjugation may be associated with nuclear regulators encoded by genes recently identified in Arabidopsis.
openaire   +2 more sources

Chronic inhibition of endoplasmic reticulum calcium-release channels and calcium-ATPase lengthens the period of hepatic clock gene Per1

Journal of Circadian Rhythms, 2011
Background The role played by calcium as a regulator of circadian rhythms is not well understood. The effect of the pharmacological inhibition of the ryanodine receptor (RyR), inositol 1,4,5-trisphosphate receptor (IP3R), and endoplasmic-reticulum Ca2 ...
Díaz-Muñoz Mauricio, Báez-Ruiz Adrián   +1 more
doaj   +1 more source

Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation [PDF]

Open Biology, 2017
The circadian clock regulates physiological processes central to growth and survival. To date, most plant circadian clock studies have relied on diurnal transcriptome changes to elucidate molecular connections between the circadian clock and observable ...
Alexander Graf, Diana Coman, R. Glen Uhrig, Sean Walsh, Anna Flis, Mark Stitt, Wilhelm Gruissem   +6 more
doaj   +1 more source

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

Protein interaction networks of the mammalian core clock proteins

, 2022
Circadian rhythm is a 24-h cycle that regulates the biochemical and behavioral changes of organisms. It controls a wide range of functions, from gene expression to behavior, allowing organisms to anticipate daily changes in their environment. In mammals, circadian rhythm is generated by a complex transcriptional and translational feedback loop ...
Kavakli, Ibrahim Halil, Ozturk, Nuri, Baris, Ibrahim   +2 more
openaire   +3 more sources

Circadian clock protein Rev-erbα regulates neuroinflammation [PDF]

Proceedings of the National Academy of Sciences, 2019
Circadian dysfunction is a common attribute of many neurodegenerative diseases, most of which are associated with neuroinflammation. Circadian rhythm dysfunction has been associated with inflammation in the periphery, but the role of the core clock in neuroinflammation remains poorly understood. Here we demonstrate that Rev-erbα, a nuclear
Percy Griffin, Julie M. Dimitry, Patrick W. Sheehan, Brian V. Lananna, Chun Guo, Michelle L. Robinette, Matthew E. Hayes, Michelle R. Cedeño, Collin J. Nadarajah, Lubov A. Ezerskiy, Marco Colonna, Jinsong Zhang, Adam Q. Bauer, Thomas P. Burris, Erik S. Musiek   +14 more
openaire   +2 more sources

Influences of desflurane on the central and hepatic circadian clock persist at 24 hours following anaesthesia in rats [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Circadian rhythm disturbances caused by anaesthesia may be one of the important reasons of many disturbances following surgery. The effects of 6% desflurane on suprachiasmatic nucleus (SCN), liver, and pancreas PER2, CRY1, BMAL, and CLOCK circadian ...
Ilknur Hatice AKBUDAK, Ozgen KILIC-ERKEK, Melek BOR-KUCUKATAY   +2 more
doaj   +1 more source