Results 91 to 100 of about 173,423,441 (192)

In the Midst of a Cytokine Storm—The Hemophagocytic Syndrome (Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Hemophagocytic syndrome (HPS)/hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome characterized by immune dysregulation, cytokine overproduction, hemophagocytosis, cytopenias, and multiorgan dysfunction.
Joanne B. Messick
wiley   +1 more source

Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study

Translational Oncology
Importance: Gastric cancer is often diagnosed at an advanced stage and at order age, identification of high-risk population is needed for detection of early-stage gastric cancer.
Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li   +6 more
doaj   +1 more source

Algorithms in Allergy: Treatment of Hypereosinophilic Syndromes, 2026 Update

Allergy, EarlyView.
Guillaume Lefèvre, Florence Roufosse, Giacomo Emmi, Andreas Reiter, Emmanuel Ledoult, Jean‐Emmanuel Kahn   +5 more
wiley   +1 more source

Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes: a prospective cohort study

Cardiovascular Diabetology
Background Clonal hematopoiesis of indeterminate potential (CHIP) was associated with diabetes and cardiovascular diseases (CVD). However, the effect of CHIP on CVD have not been evaluated among patients with diabetes, and whether maintaining the healthy
Ying Sun, Yuefeng Yu, Lingli Cai, Bowei Yu, Wenying Xiao, Xiao Tan, Yu Wang, Yingli Lu, Ningjian Wang   +8 more
doaj   +1 more source

Association between chronic kidney disease and the risk of myelodysplastic syndromes: A large claims database study in Japan

British Journal of Haematology, EarlyView.
Yuta Baba, Takehiko Sambe, Tetsuya Fukuda, Tatsunori Oguchi, Kenji Momo   +4 more
wiley   +1 more source

Safety, Pharmacokinetics, and Efficacy Study of Porcine and Rabbit Antithymocyte Globulin in the Treatment of Patients With Severe Aplastic Anemia: A Multicenter, Prospective, Randomized, Open‐Label Clinical Trial

MedComm, Volume 7, Issue 11, November 2026.
This prospective trial compared porcine‐ATG and rabbit‐ATG for severe aplastic anemia. Both agents peaked on Day 5, with faster clearance for rabbit‐ATG. Porcine‐ATG induced an early stable neutrophil rise, whereas rabbit‐ATG caused an initial neutrophil drop.
Yawen Zhang, Yingying Zhang, Yuemin Gong, Yu Sun, Guangsheng He   +4 more
wiley   +1 more source

The role of the PPM1D gene in the carcinogenesis of myeloid neoplasms: molecular mechanisms and prospects for targeted therapy

Сибирский онкологический журнал
Objective: to summarize the accumulated knowledge on the role of PPM1D phosphatase in clonal hematopoiesis and the pathogenesis of hematological malignancies, particularly in acute myeloid leukemia, as well as to evaluate the feasibility of therapeutic ...
E. D. Kolosova, D. A. Bogdanova, O. N. Demidov   +2 more
doaj   +1 more source

Liquid Biopsy: Past, Present, and Future

MedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu, Dianjie Zeng, Keran Zhao, Yuxi Wang, Huijie Hu, Fei Deng, Yinhuai Wang, Liya Sun, Liangmin Fu   +8 more
wiley   +1 more source

Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar

Aging Cell, Volume 25, Issue 11, November 2026.
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley   +1 more source

The effect of clonal hematopoiesis on long-term outcomes in patients undergoing coronary artery bypass grafting

BMC Medicine
Background Clonal hematopoiesis of indeterminate potential (CHIP), characterized by age-related somatic mutations in hematopoietic stem and progenitor cells, has been identified as a potential risk factor for cardiovascular events and mortality. However,
Zhiwei Zeng, Fangzhou Li, Shujie Gai, Runze Chen, Peng Wang, Juncheng Wang, Yuhui Yang, Jinhua Chen, Xingyi Zhang, Xueying Wang, Yi Han, Chuxiang Lei, Xi Li, Hanning Liu, Zhe Zheng   +14 more
doaj   +1 more source