Results 71 to 80 of about 6,041 (204)
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
American Journal of Hematology, EarlyView.CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Journal of Genetic Engineering and Biotechnology, 2021 Background Cardiovascular diseases (CVDs) are the leading cause of mortality in India. Residual risk exists in patients receiving optimal guideline-directed medical therapy.
Nagendra Boopathy Senguttuvan +4 more
doaj +1 more source
Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao +8 more
wiley +1 more source
Cell Reports, 2019 Summary: Clonal hematopoiesis of indeterminate potential (CHIP) is caused by recurrent somatic mutations leading to clonal blood cell expansion. However, direct evidence of the fitness of CHIP-mutated human hematopoietic stem cells (HSCs) in blood ...
Christina A. Ortmann +20 more
doaj +1 more source
Incorporating Management of Clonal Hematopoiesis of Indeterminate Potential Into Cardiovascular Practice. [PDF]
CirculationOren O, Libby P.
europepmc +3 more sources
Clonal hematopoiesis and atherosclerotic cardiovascular disease: A primer. [PDF]
, 2023 Despite current standards of care, a considerable risk of atherosclerotic cardiovascular disease remains in both primary and secondary prevention. In this setting, clonal hematopoiesis driven by somatic mutations has recently emerged as a relatively ...
Fuster, Jose J., Zuriaga, María A
core +1 more source
Immunophenotypic characteristics of plasma cells in POEMS syndrome
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang +6 more
wiley +1 more source
Scientific Reports, 2022 Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the presence of clones of mutated blood cells without overt blood diseases.
Francesco Vieceli Dalla Sega +19 more
doaj +1 more source
New approaches to idiopathic neutropenia in the era of clonal hematopoiesis [PDF]
, 2023 Isolated chronic idiopathic neutropenia (CIN) is a rare disease with multiple contributing etiologies that must be ruled out before establishing a diagnosis. We studied clinical and molecular data of 238 consecutive adult patients with CIN.
Bahaj W. S. +5 more
core +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source