Results 21 to 30 of about 6,041 (204)

Extramedullary Clonal Hematopoiesis with Indeterminate Potential [PDF]

Clinical Lymphoma Myeloma and Leukemia, 2021
Clinical Practice Points • We present here the case of an otherwise healthy male patient with paravertebral tumors with histological findings of extramedullary hematopoiesis (EH). • The hematological assessment could not confirm a hematological disease.
Florian, Ramdohr, Astrid, Monecke, Madlen, Jentzsch, Thomas, Zehrfeld, Gudrun, Borte, Sebastian, Schwind, Georg-Nikolaus, Franke, Klaus H, Metzeler, Uwe, Platzbecker, Vladan, Vucinic   +9 more
openaire   +2 more sources

Electrocardiographic Age and Clonal Hematopoiesis of Indeterminate Potential. [PDF]

JACC Basic Transl Sci
Khurshid S, Friedman S, Rathod R, Uddin MM, Maddah M, Honigberg MC, Natarajan P, Ellinor PT.   +7 more
europepmc   +4 more sources

Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Disease [PDF]

Current Oncology Reports, 2020
The purpose of this review article is to summarize the preclinical and clinical evidence supporting the notion of clonal hematopoiesis of indeterminate potential (CHIP), highlight current knowledge gap, and provide future directions.Epidemiological studies show that advanced age is a major risk factor for the development of cardiovascular disease (CVD)
Kumar, Preetham, Kopecky, Stephen L, Yang, Eric H, Oren, Ohad   +3 more
openaire   +3 more sources

CLONAL HEMATOPOIESIS: ROLE IN HEMATOLOGIC NON-HEMATOLOGIC

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Hematopoietic stem cells (HSCs) ensure the coordinated and balanced production of all hematopoietic cell types throughout life. Aging is associated with a gradual decline of the self-renewal and regenerative potential of HSCs and with the development of
Ugo Testa, Germana Castelli , Elvira Pelosi   +2 more
doaj   +1 more source

Clonal Hematopoiesis of Indeterminate Potential [PDF]

Deutsches Ärzteblatt international, 2016
Patients with cytopenia are increasingly undergoing molecular genetic tests of periperal blood or bone marrow for diagnostic purposes. These tests can detect genetic mutations that do not have any morphological correlate in hematologic neoplasia such as myelo - dysplastic syndrome (MDS). A new entity was recently defined to lessen the risk of incorrect
Michael, Heuser, Felicitas, Thol, Arnold, Ganser   +2 more
openaire   +2 more sources

A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology

Cancers, 2022
Clonal hematopoiesis of indeterminate potential can be defined as genetic mutations that correlate in hematologic neoplasia such as myelodysplastic syndrome. Patients with cytopenia increasingly undergo molecular genetic tests of peripheral blood or bone marrow for diagnostic purposes.
Maroun Bou Zerdan, Lewis Nasr, Ludovic Saba, Paul Meouchy, Nadine Safi, Sabine Allam, Jenish Bhandari, Chakra P. Chaulagain   +7 more
openaire   +2 more sources

Common in atherogenesis and carcinogenesis: clonal hematopoiesis

Российский кардиологический журнал, 2023
Clonal hematopoiesis is a common age-dependent state accompanied by the expansion of mutant hematopoietic stem cells as a result of somatic mutations and is associated with a high risk of hematopoietic neoplasms and cardiovascular diseases.
A. A. Sleptsov, M. S. Nazarenko, V. Р. Puzyrev   +2 more
doaj   +1 more source

Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Health. [PDF]

Cardiol Clin
Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related phenomenon in which somatic mutations lead to clonal expansion of hematopoietic stem cells without the development of hematologic abnormalities. A growing body of literature demonstrates an association between CHIP and cardiovascular disease.
Raddatz MA, Pershad Y, Parker AC, Bick AG.   +3 more
europepmc   +3 more sources

Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review [PDF]

, 2020
Some random mutations can confer a selective advantage to a hematopoietic stem cell. As a result, mutated hematopoietic stem cells can give rise to a significant proportion of mutated clones of blood cells.
Campo, G., Fortini, F., Marracino, L., Papa, V., Rizzo, P., Vaccarezza, Mauro, Vieceli Dalla Sega, F   +6 more
core   +1 more source

Coronary atherosclerosis scoring with semiquantitative CCTA risk scores for prediction of major adverse cardiac events: Propensity score-based analysis of diabetic and non-diabetic patients. [PDF]

, 2020
AIMS:We aimed to compare semiquantitative coronary computed tomography angiography (CCTA) risk scores - which score presence, extent, composition, stenosis and/or location of coronary artery disease (CAD) - and their prognostic value between patients ...
Achenbach, Stephan, Al-Mallah, Mouaz H, Andreini, Daniele, Bax, Jeroen J, Berman, Daniel S, Budoff, Matthew J, Cademartiri, Filippo, Callister, Tracy Q, Chang, Hyuk-Jae, Chinnaiyan, Kavitha, Chow, Benjamin JW, Cury, Ricardo C, de Araújo Gonçalves, Pedro, DeLago, Augustin, Dimitriu-Leen, Aukelien C, Feuchtner, Gudrun, Gransar, Heidi, Hadamitzky, Martin, Hausleiter, Joerg, Jones, Erica C, Kaufmann, Philipp A, Kim, Yong-Jin, Leipsic, Jonathon A, Lin, Fay Y, Lu, Yao, Maffei, Erica, Marques, Hugo, Min, James K, Peña, Jessica M, Pontone, Gianluca, Raff, Gilbert L, Rubinshtein, Ronen, Scholte, Arthur JHA, Shaw, Leslee J, Smit, Jeff M, van den Hoogen, Inge J, van Rosendael, Alexander R, Villines, Todd C   +37 more
core   +1 more source