Results 91 to 100 of about 102,010 (264)

Longitudinal sequencing of HIV-1 infected patients with low-level viremia for years while on ART shows no indications for genetic evolution of the virus [PDF]

, 2017
HIV-infected patients on antiretroviral therapy (ART) may present low-level viremia (LLV) above the detection level of current viral load assays.
Dauwe, Kenny, Demecheleer, Els, Dinakis, Sylvie, Hebberecht, Laura, Mortier, Virginie, Vancoillie, Leen, Vaneechoutte, Dries, Verhofstede, Chris   +7 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Is Clonal Integration a Buffer for the Stress of Resource Acquisition Depletion in Eichhornia crassipes (Pontederiaceae) Ramets?

Stresses
Natural selection favors the allocation of finite resources to different functions maximizing fitness. In this sense, some functions may decrease whereas others increase when resources are limited in a process called a trade-off. However, a great variety
Guilherme Ramos Demetrio, Dalton Serafim, Flávia de Freitas Coelho   +2 more
doaj   +1 more source

Survival and growth of epiphytic ferns depend on resource sharing

Frontiers in Plant Science, 2016
Locally available resources can be shared within clonal plant systems through physiological integration, thus enhancing their survival and growth.
Hua-Zheng eLu, Hua-Zheng eLu, Liang eSong, Wen-Yao eLiu, Xing-Liang eXu, Yue-Hua eHu, Xian-Meng eShi, Xian-Meng eShi, Su eLi, Wen-Zhang eMa, Yan-Fen eChang, Ze-Xin eFan, Shu-Gang eLu, Yi eWu, Yi eWu, Fei-Hai eYu   +15 more
doaj   +1 more source

Farming system characterization for rubber smallholders in West Kalimantan [PDF]

, 2003
Dans l'Est-Kalimantan, l'adoption de nouveau matériel végétal dépend de sa disponibilité et du coût, de l'organisation et la cohésion sociale. les exploitants sont , en général, convaincus par les bonnes performances des nouveaux clones d'hévéa.
Courbet, Philippe, Ilahang, I., Penot, Eric   +2 more
core  

Two distinct AFLP types in three populations of marram grass (Ammophila arenaria in Wales) [PDF]

, 2008
The genetic structure of marram grass populations at coastal and inland locations, 200 m apart, was investigated at three sites by means of amplified fragment length polymorphism (AFLP) DNA markers.
Cook, R., Hol, W.H.G., Skot, L., Wurff, A.W.G., van der   +3 more
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Do invasive clonal plants always benefit from clonal integration? Exploring interactions between biocontrol agents and indigenous herbivores

Biological Control
Clonal integration can help plants counter environmental stresses, but its effects on plant responses to herbivory remain unclear. We investigated how clonal integration in the invasive Alternanthera philoxeroides and the native Alternanthera sessilis ...
Yingying Tan, Wenfeng Guo, Tao Xiong, Jun Tang, Xiaoqiong Li   +4 more
doaj   +1 more source

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. [PDF]

, 2019
Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption.
Bale, Michael J, Busch, Michael P, Cox, Bryan, Deeks, Steven G, Hoh, Rebecca, Kearney, Mary F, Kulpa, Deanna A, Lackman-Smith, Carol, Maldarelli, Frank, Ptak, Roger G, Stone, Mars, Subramanian, Krupa, Wiegand, Ann, Wonderlich, Elizabeth R   +13 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source