Results 61 to 70 of about 102,191 (285)

Clonal integration of the invasive plant Wedelia trilobata (L.) Hitch in stress of flooding type combination

International Journal of Plant Biology, 2018
The clonal invasion of Wedelia trilobata (L.) Hitch has spread to edges of mangrove areas, which leads to the formation of flooding-stressed areas such as waterlogged and submergence.
Endang Saptiningsih, Kumala Dewi, Santosa Santosa, Yekti A. Purwestri   +3 more
doaj   +1 more source

Molecular recording of mammalian embryogenesis. [PDF]

, 2019
Ontogeny describes the emergence of complex multicellular organisms from single totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate relationship between self-renewal and differentiation, variation in progenitor
Adamson, Britt, Chan, Michelle M, Grosswendt, Stefanie, Jones, Matthew G, Jost, Marco, Khodaverdian, Alex, Kretzmer, Helene, Meissner, Alexander, Norman, Thomas M, Quinn, Jeffrey J, Smith, Zachary D, Weissman, Jonathan S, Yang, Dian, Yosef, Nir   +13 more
core   +2 more sources

Clonality, latency and integration of HTLV-1 in vivo [PDF]

Retrovirology, 2013
Background The HTLV-1 proviral load set point is the strongest correlate of the inflammatory and malignant diseases associated with HTLV-1. This set point appears to be determined by an equilibrium between virus-driven proliferation and CTL-mediated killing of HTLV-1-infected T cells. However, we do not know what determines the number, the abundance or
Bangham, Charles, Cook, Lucy, Laydon, Daniel, Asquith, Becca, Melamed, Anat   +4 more
openaire   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Effect of clonal integration in the invasion process of Carpobrotus edulis [PDF]

, 2016
[Resumen] Las invasiones biológicas son una de las principales amenazas para la conservación de la biodiversidad. A pesar de los avances de los últimos años, todavía no están claros los mecanismos que subyacen en el proceso invasor de la plantas.
Regueiro Teijido, Miguel
core  

Loci specific epigenetic drug sensitivity. [PDF]

, 2020
Therapeutic targeting of epigenetic modulators offers a novel approach to the treatment of multiple diseases. The cellular consequences of chemical compounds that target epigenetic regulators (epi-drugs) are complex.
Pilko, Anna, Wollman, Roy, Zhang, Thanutra   +2 more
core   +1 more source

Genomic insights into the rapid emergence and evolution of MDR in Staphylococcus pseudintermedius. [PDF]

, 2014
OBJECTIVES: MDR methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains have emerged rapidly as major canine pathogens and present serious treatment issues and concerns to public health due to their, albeit low, zoonotic potential. A further
A. J. McCarthy, A. Loeffler, A. Waller, B. Leggett, Bannoehr, Besier, Black, Bond, Croucher, D. H. Lloyd, Darling, De Lucia, E. M. Harrison, Feil, Feng, Geoghegan, Gortel, J. A. Lindsay, K. Stanczak-Mrozek, Kadlec, Koser, Loeffler, Loeffler, M. A. Holmes, Magiorakos, Noguchi, Prescott, Quail, Roberts, Ruscher, Rutherford, Soedarmanto   +31 more
core   +3 more sources

Clonal integration benefits Calystegia soldanella in heterogeneous habitats

AoB PLANTS
Abstract Abstract. Land-use change and tourism development have seriously threatened the ecosystems of coastal protection forests and beaches. Light and nutrients are spatially heterogeneously distributed between the two ecosystems. Clonal plants, such as Calystegia soldanella, which play a crucial role in maintaining the ecological ...
Mingyan Li, Siyu Jiang, Tong Wang, Hui Wang, Lijun Xing, Haimei Li, Yingkun Sun, Xiao Guo   +7 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source