Results 11 to 20 of about 746,964 (209)

Identification of TCR Vβ11-2-Dβ1-Jβ1-1 T cell clone specific for WT1 peptides using high-throughput TCRβ gene sequencing

open access: yesBiomarker Research, 2019
We previously identified a TCR Vβ21 T cell clone which was specific to CML patients, and demonstrated that TCR Vα13/β21 gene-modified CD3+ T cells had specific cytotoxicity for HLA-A11+ K562 cells.
Yikai Zhang   +5 more
doaj   +1 more source

Modeling large fluctuations of thousands of clones during hematopoiesis: The role of stem cell self-renewal and bursty progenitor dynamics in rhesus macaque. [PDF]

open access: yesPLoS Computational Biology, 2018
In a recent clone-tracking experiment, millions of uniquely tagged hematopoietic stem cells (HSCs) and progenitor cells were autologously transplanted into rhesus macaques and peripheral blood containing thousands of tags were sampled and sequenced over ...
Song Xu   +3 more
doaj   +1 more source

Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]

open access: yes, 1987
We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bode   +28 more
core   +1 more source

Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells

open access: yesBMC Cancer, 2017
Background The biological phenomenon of cell fusion has been associated with cancer progression since it was determined that normal cell × tumor cell fusion-derived hybrid cells could exhibit novel properties, such as enhanced metastatogenic capacity or ...
Daria Gauck   +4 more
doaj   +1 more source

Characterization of interstitial stem cells in hydra by cloning [PDF]

open access: yes, 1977
A procedure has been developed for cloning interstitial stem cells from hydra. Clones are prepared by introducing small numbers of viable cells into aggregates of nitrogen mustard-inactivated host tissue.
David, Charles N., Murphy, Susan
core   +1 more source

Constitutive overexpression of a novel 21 kDa protein by Hodgkin Lymphoma and Aggressive Non-Hodgkin Lymphomas

open access: yesMolecular Cancer, 2008
Background CD30, a 120 kDa surface phosphorylated protein is a member of tumour necrosis/nerve growth factor receptor (TNF/NGFR) family and constitutively expressed by Hodgkin and Reed-Sternberg (HRS) cells of Hodgkin lymphoma (HL) and the neoplastic ...
Gascoyne Randy D   +5 more
doaj   +1 more source

Screening and development of monoclonal antibodies for identification of ferret T follicular helper cells

open access: yesScientific Reports, 2021
The ferret is a key animal model for investigating the pathogenicity and transmissibility of important human viruses, and for the pre‐clinical assessment of vaccines.
Wenbo Jiang   +9 more
doaj   +1 more source

Feedback regulation of methyl methanesulfonate and ultraviolet-sensitive gene clone 81 via ATM/Chk2 pathway contributes to the resistance of MCF-7 breast cancer cells to cisplatin

open access: yesTumor Biology, 2017
The methyl methanesulfonate and ultraviolet-sensitive gene clone 81 protein is a structure-specific nuclease that plays important roles in DNA replication and repair.
Juan Lv   +4 more
doaj   +1 more source

Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]

open access: yes, 2012
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Alicia R. Feagins   +15 more
core   +1 more source

Difference in susceptibility to lysis between clones of the Y strain of Trypanosoma cruzi

open access: yesMemorias do Instituto Oswaldo Cruz, 1993
Three clones isolated from the Y strain of Trypanosoma cruzi - YP1, YP2 and YP3 - were adapted to in vitro cultivation in VERO cells. The recovery of the parasites from the Y strain and clone YP3 was similar after 24 hr of contact with cells (3.2% and 2 ...
Erika M. Braga   +3 more
doaj   +1 more source

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