Results 1 to 10 of about 82,588 (312)

Evaluating the transition from dexmedetomidine to clonidine for agitation management in the intensive care unit

SAGE Open Medicine, 2015
Objectives: Limited literature exists examining the use of enteral clonidine to transition patients from dexmedetomidine for management of agitation. The aim of this study was to evaluate dexmedetomidine discontinuation within 8 h of enteral clonidine ...
Kimberly Terry, Rachel Blum, Paul Szumita   +2 more
doaj   +2 more sources

The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses [PDF]

BMC Pharmacology and Toxicology, 2018
Background The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium.
Karen Roksund Hov, Bjørn Erik Neerland, Anders Mikal Andersen, Øystein Undseth, Vegard Bruun Wyller, Alasdair M. J. MacLullich, Eva Skovlund, Eirik Qvigstad, Torgeir Bruun Wyller   +8 more
doaj   +4 more sources

Evaluation of clonidine as an adjuvant to brachial plexus block and its comparison with tramadol

Journal of Anaesthesiology Clinical Pharmacology, 2017
Background and Aims: It has been reported that clonidine when used as an additive in a dose of 90 μg in adults increases the duration of peripheral nerve blocks.
Prakash Kelika, Jamkar Maya Arun
doaj   +2 more sources

The Addition of Intrathecal Clonidine to Reduce Medication-Related Side-Effects in Cancer Pain: A Retrospective Cohort Study [PDF]

Journal of Pain Research
Evgeny Bulat,1 Rahul Chaturvedi,2 Peyton Johnson,2 Neal Rakesh,3 Amitabh Gulati3 1Pain Treatment Specialists, VIP Medical Group, New York, NY, USA; 2Department of Anesthesiology, NewYork-Presbyterian/Weill Cornell Medical Center, New York, NY, USA ...
Bulat E, Chaturvedi R, Johnson P, Rakesh N, Gulati A   +4 more
doaj   +2 more sources

Clonidine Use for the Treatment of Nightmares in Posttraumatic Stress Disorder

Case Reports in Psychiatry, 2022
Introduction. While clonidine is used clinically for the treatment of nightmares in posttraumatic stress disorder (PTSD), few case reports demonstrating this indication exist, and there have been few studies investigating clonidine’s mechanism of action ...
Jill S. Bange, Kelly E. Melvin
doaj   +1 more source

Clonidine

Reactions Weekly
Patel P, Saadabadi A.
europepmc   +3 more sources

Stability of clonidine hydrochloride in an oral powder form compounded for pediatric patients in Japan

Journal of Pharmaceutical Health Care and Sciences, 2021
Background Clonidine hydrochloride is used to treat sedative agent withdrawals, malignant hypertension, and anesthesia complications. Clonidine is also prescribed off-label to pediatric patients at a dose of 1 μg/kg.
Jumpei Saito, Takehisa Hanawa, Takahiro Matsumoto, Nozomi Yoshikawa, Tsutomu Harada, Kana Iwahashi, Hidefumi Nakamura, Akimasa Yamatani   +7 more
doaj   +1 more source

A randomized study of comparison between Intravenous infusion of 0.5 mcg/kg of clonidine and 1 mcg/kg of clonidine on hemodynamic stress response to pnuemo peritoneum and intubation response during laparoscopic surgeries in a tertiary care hospital in a sub urban population

Asian Journal of Medical Sciences, 2022
Background: The laparoscopic surgical procedure has made remarkable changes in the surgical field. Conditions, such as pneumoperitoneum, has an impact on several homeostatic systems.
Sindhuja Somasundaram , Selvakumaran Pannirselvam   +1 more
doaj   +1 more source

Effects of α2-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum.

PLoS ONE, 2022
The sympathetic nervous system is highly involved in the regulation of gastrointestinal functions such as luminal alkalinisation and fluid absorption. However, the exact mechanisms are not clear.
Olof Nylander, Markus Sjöblom, John Sedin, David Dahlgren   +3 more
doaj   +1 more source

Efficacy and Safety of Clonidine in the Treatment of Acute Mania in Bipolar Disorder: A Systematic Review

Brain Sciences, 2023
Clonidine, an alpha-2 adrenergic agonist, has been proposed as an antimanic agent that acts by reducing noradrenergic transmission. We conducted a systematic review to examine the efficacy and safety of clonidine for acute mania/hypomania.
Prakamya Singal, Nicolas A. Nuñez, Boney Joseph, Leslie C. Hassett, Ashok Seshadri, Balwinder Singh   +5 more
doaj   +1 more source