Results 1 to 10 of about 53,918 (277)
SAGE Open Medicine, 2015 Objectives: Limited literature exists examining the use of enteral clonidine to transition patients from dexmedetomidine for management of agitation. The aim of this study was to evaluate dexmedetomidine discontinuation within 8 h of enteral clonidine ...
Kimberly Terry +2 more
doaj +2 more sources
Topical Clonidine Accelerates Cutaneous Wound Healing in Diabetic Rats by Regulating the Expression of Related Cytokine Signaling [PDF]
Current Issues in Molecular BiologyBased on the analgesic and anti-inflammatory effects of clonidine in previous studies, we hypothesized that clonidine could accelerate wound healing in rats by regulating the expression of related cytokines.
Thi-Chau-Loan Phan +4 more
doaj +2 more sources
Clonidine for post-traumatic stress disorder: a systematic review of the current evidence [PDF]
European Journal of PsychotraumatologyBackground: Clonidine is a centrally acting anti-adrenergic agent that may have applications in post-traumatic stress disorder (PTSD), particularly for sleep.Objective: In this systematic review, we aimed to summarize the effect of clonidine on sleep ...
Mattia Marchi +2 more
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Clonidine Use for the Treatment of Nightmares in Posttraumatic Stress Disorder
Case Reports in Psychiatry, 2022 Introduction. While clonidine is used clinically for the treatment of nightmares in posttraumatic stress disorder (PTSD), few case reports demonstrating this indication exist, and there have been few studies investigating clonidine’s mechanism of action ...
Jill S. Bange, Kelly E. Melvin
doaj +1 more source
Journal of Pharmaceutical Health Care and Sciences, 2021 Background Clonidine hydrochloride is used to treat sedative agent withdrawals, malignant hypertension, and anesthesia complications. Clonidine is also prescribed off-label to pediatric patients at a dose of 1 μg/kg.
Jumpei Saito +7 more
doaj +1 more source
Asian Journal of Medical Sciences, 2022 Background: The laparoscopic surgical procedure has made remarkable changes in the surgical field. Conditions, such as pneumoperitoneum, has an impact on several homeostatic systems.
Sindhuja Somasundaram +1 more
doaj +1 more source
Effects of α2-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum.
PLoS ONE, 2022 The sympathetic nervous system is highly involved in the regulation of gastrointestinal functions such as luminal alkalinisation and fluid absorption. However, the exact mechanisms are not clear.
Olof Nylander +3 more
doaj +1 more source
Pharmaceutics, 2020 The intravenous pharmacotherapy of critically ill patients is extremely challenging due to the high number of drugs administered. We therefore evaluated the physicochemical compatibility of combinations of clonidine with drugs frequently used in an ...
Anna Katharina Koller +2 more
doaj +1 more source
Efficacy of low dose intravenous dexmedetomidine versus clonidine in treatment of shivering during caesarean section under spinal anaesthesia: a double blind randomized controlled trial [PDF]
New Indian Journal of OBGYN, 2023 Objectives: Dexmedetomidine and clonidine have been used to prevent and treat shivering after spinal anaesthesia. A double blind randomized controlled trial was conducted to compare the efficacy and safety of low dose intravenous dexmedetomidine and ...
Karamchand Basumatary +5 more
doaj +1 more source
Brain Sciences, 2023 Clonidine, an alpha-2 adrenergic agonist, has been proposed as an antimanic agent that acts by reducing noradrenergic transmission. We conducted a systematic review to examine the efficacy and safety of clonidine for acute mania/hypomania.
Prakamya Singal +5 more
doaj +1 more source