Results 21 to 30 of about 32,197 (228)

Clonidine versus Captopril for Severe Postpartum Hypertension: A Randomized Controlled Trial. [PDF]

PLoS ONE, 2017
Changes during the puerperium are still unclear, particularly in women with hypertension. The choice of antihypertensives, both to control very high blood pressure episodes and to keep blood pressure stable, also requires further elucidation.
Carlos Noronha Neto C, Sabina S B Maia, Leila Katz, Isabela C Coutinho, Alex R Souza, Melania M Amorim   +5 more
doaj   +1 more source

Comparison of Fentanyl and Clonidine for Attenuation of the Haemodynamic Response to Laryngocopy and Endotracheal Intubation [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Laryngoscopy and tracheal intubation after the induction of anaesthesia, are nearly always associated with a sympathetic hyperactivity.
Sameenakousar, Mahesh, K.V. Srinivasan
doaj   +1 more source

Antihypertensive Effect of Clonidine [PDF]

Circulation Research, 1971
Clonidine hydrochloride is a sympathetic inhibitor with central site of action. The antihypertensive effect in man in the supine position is associated with a decrease in cardiac output and no consistent changes in total peripheral resistance. In the standing position, however, in addition to the decrease in cardiac output, a fall in total peripheral ...
Charles Swartz, Gaddo Onesti, Virgilio Paz-Martinez, Allan B. Schwartz, Kwan E. Kim   +4 more
openaire   +3 more sources

Response to low-dose intrathecal clonidine in septuagenarians undergoing sub-umbilical surgeries: A study

Saudi Journal of Anaesthesia, 2015
Clonidine, an alpha-2-adrenergic agonist, may have a clinically relevant analgesic action but also a hypotensive action, when administered spinally. Aim: To evaluate the analgesic and circulatory effects of low-dose intrathecal clonidine co-administered ...
Jayashree Sen, Bitan Sen
doaj   +1 more source

Topical Clonidine Accelerates Cutaneous Wound Healing in Diabetic Rats by Regulating the Expression of Related Cytokine Signaling

Current Issues in Molecular Biology
Based on the analgesic and anti-inflammatory effects of clonidine in previous studies, we hypothesized that clonidine could accelerate wound healing in rats by regulating the expression of related cytokines.
Thi-Chau-Loan Phan, Yi-Syuan Chiang, Ming-Jai Su, Yao-Jen Liang, Shiow-Jen Juang   +4 more
doaj   +1 more source

The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses

BMC Pharmacology and Toxicology, 2018
Background The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium.
Karen Roksund Hov, Bjørn Erik Neerland, Anders Mikal Andersen, Øystein Undseth, Vegard Bruun Wyller, Alasdair M. J. MacLullich, Eva Skovlund, Eirik Qvigstad, Torgeir Bruun Wyller   +8 more
doaj   +1 more source

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source

Gabapentin versus Clonidine Premedication for Haemodynamic Stability and Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomised Double-blind Control Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laparoscopic cholecystectomy is associated with haemodynamic stress responses and significant postoperative pain due to CO2 insufflation and peritoneal irritation.
Mahima Manchanda, Seema Tikku Sharma, Kanika Sachdeva, Gurpreet Kaur Atwal, Neha Mehra   +4 more
doaj   +1 more source

Practical management of repeated life‐threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review

Epileptic Disorders, EarlyView.
Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani, Livia Pisciotta, Michela Stagnaro, Maria Margherita Mancardi, Elisabetta Lampugnani, Luca Manfredini, Lino Nobili, Edvige Veneselli, Elisa De Grandis   +8 more
wiley   +1 more source

Generalized target behavior reductions and maintenance of effects following an augmented competing stimulus assessment sequence

Journal of Applied Behavior Analysis, EarlyView.
Abstract Competing stimulus assessments are one technology that aids in the development of treatment for automatically reinforced behavior. However, competing stimulus assessments do not always yield robust results. Stereotypic behaviors of different subtypes may require procedural modifications to successfully identify competing stimuli.
Samantha L. Breeman, Jason C. Vladescu, Tina M. Sidener, Ruth M. DeBar, Danielle Gureghian   +4 more
wiley   +1 more source