Results 41 to 50 of about 82,588 (312)

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery [PDF]

, 2008
BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients.
Baraka, Anis, El-Katib, Mohamad, Kassem, Rida, Maaliki, Hilal, Nahleh, Nezih, Struys, Michel, Zeidan, Ahed   +6 more
core   +2 more sources

Topical Clonidine Accelerates Cutaneous Wound Healing in Diabetic Rats by Regulating the Expression of Related Cytokine Signaling

Current Issues in Molecular Biology
Based on the analgesic and anti-inflammatory effects of clonidine in previous studies, we hypothesized that clonidine could accelerate wound healing in rats by regulating the expression of related cytokines.
Thi-Chau-Loan Phan, Yi-Syuan Chiang, Ming-Jai Su, Yao-Jen Liang, Shiow-Jen Juang   +4 more
doaj   +1 more source

Patient anxiety and modern elective surgery: a literature review [PDF]

, 2003
Medical advances have led to a considerable rise in the level of elective surgery undertaken as day-case surgery and with minimal hospital stay. However, amid such advances, preoperative psychological care has remained relatively static.
Mitchell, MJ
core   +1 more source

Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation) study.

Health Technology Assessment, 2014
BACKGROUND Children in paediatric intensive care units (PICUs) require analgesia and sedation but both undersedation and oversedation can be harmful. OBJECTIVE Evaluation of intravenous (i.v.) clonidine as an alternative to i.v. midazolam.
Andrew J. Wolf, A. McKay, C. Spowart, H. Granville, A. Boland, S. Petrou, A. Sutherland, C. Gamble   +7 more
semanticscholar   +1 more source

Response to low-dose intrathecal clonidine in septuagenarians undergoing sub-umbilical surgeries: A study

Saudi Journal of Anaesthesia, 2015
Clonidine, an alpha-2-adrenergic agonist, may have a clinically relevant analgesic action but also a hypotensive action, when administered spinally. Aim: To evaluate the analgesic and circulatory effects of low-dose intrathecal clonidine co-administered ...
Jayashree Sen, Bitan Sen
doaj   +1 more source

The implausibility of ‘usual care’ in an open system: sedation and weaning practices in Paediatric Intensive Care Units (PICUs) in the United Kingdom (UK) [PDF]

, 2015
Background: The power of the randomised controlled trial depends upon its capacity to operate in a closed system whereby the intervention is the only causal force acting upon the experimental group and absent in the control group, permitting a valid ...
B Ambuel, B Blackwood, B Blackwood, B Blackwood, B Blackwood, Bronagh Blackwood, C Maloney, CJL Newth, D Bieri, D Macrae, DL Jackson, E Ista, E Ista, F Frutos-Vivar, FK Foronda, FW Moler, J Rycroft-Malone, J Rycroft-Malone, J Rycroft-Malone, JA Durlak, K Harron, L Kohn, L Rose, LS Franck, Lyvonne Tume, M Cunliffe, NJ Vet, P O’Halloran, PA Jouvet, RP Dellinger, S Chawla, S Playfor, SI Merkel, SW Krechel, YN Poh   +34 more
core   +1 more source

Comparison of clonidine and dexmedetomidine for short-term sedation of intensive care unit patients

Indian Journal of Critical Care Medicine, 2014
Background and Objectives: Patients on mechanical ventilation in intensive care unit (ICU) are often uncomfortable because of anxiety, pain, and endotracheal intubation; therefore, require sedation. Alpha-2 agonists are known to produce sedation.
U. Srivastava, M. Sarkar, Aditya Kumar, Amrita Gupta, A. Agarwal, T. Singh, Vivek Badada, Yogita Dwivedi   +7 more
semanticscholar   +1 more source

Clonidine Overdose as an Unusual Cause of Heart Failure

Journal of Investigative Medicine High Impact Case Reports, 2022
Clonidine is used as an antihypertensive medication due to its effect on decreasing peripheral vascular resistance and therefore lowering blood pressure.
Jagdeep Bhullar PharmD, Arti Patel MS4, Jaagruthi Chitithoti DO, Frederick Venter MD, Theingi Win MD, Fowrooz Joolhar MD   +5 more
doaj   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source