Results 61 to 70 of about 5,018,281 (306)
Ab initio multiple cloning algorithm for quantum nonadiabatic molecular dynamics.
We present a new algorithm for ab initio quantum nonadiabatic molecular dynamics that combines the best features of ab initio Multiple Spawning (AIMS) and Multiconfigurational Ehrenfest (MCE) methods. In this new method, ab initio multiple cloning (AIMC),
D. Makhov+3 more
semanticscholar +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
On the Relationship of Inconsistent Software Clones and Faults: An Empirical Study [PDF]
Background: Code cloning - copying and reusing pieces of source code - is a common phenomenon in software development in practice. There have been several empirical studies on the effects of cloning, but there are contradictory results regarding the connection of cloning and faults.
arxiv +1 more source
Molecular Cloning of Sucrose Isomerase Gene and Agrobacterium-Mediated Genetic Transformation of Potato (Solanum tuberosum L.) Plants [PDF]
Potato (Solanum tuberosum L.) is one of the most common and important food sources on the planet, and they essential as a staple dietary item for much of the world's population. Potatoes contain carbohydrates, which lead to high blood sugar.
Soliman, H. I. (Hemaid)
core
A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the current through alpha 7-channels is carried by Ca2+.
Philippe Sbgu&a+4 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Molecular cloning is a process that manipulates the spider silk sequence to select for a proper sequence size and specific vector into which it can be expressed.
Worley, Josh
core +1 more source
Rapid construction of mycobacterial mutagenesis vectors using ligation-independent cloning [PDF]
Targeted mutagenesis is one of the major tools for determining the function of a given gene and its involvement in bacterial pathogenesis. In mycobacteria, gene deletion is often accomplished by using allelic exchange techniques that commonly utilise a ...
Balhana, Ricardo+4 more
core +2 more sources
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.
A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major beta/A4-protein (A beta) fragment, two unknown peptides ...
K. Uéda+9 more
semanticscholar +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source