Results 61 to 70 of about 5,018,281 (306)

Ab initio multiple cloning algorithm for quantum nonadiabatic molecular dynamics.

open access: yesJournal of Chemical Physics, 2014
We present a new algorithm for ab initio quantum nonadiabatic molecular dynamics that combines the best features of ab initio Multiple Spawning (AIMS) and Multiconfigurational Ehrenfest (MCE) methods. In this new method, ab initio multiple cloning (AIMC),
D. Makhov   +3 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

On the Relationship of Inconsistent Software Clones and Faults: An Empirical Study [PDF]

open access: yesProc. 23rd International Conference on Software Analysis, Evolution, and Reengineering (SANER). IEEE, 2016, 2016
Background: Code cloning - copying and reusing pieces of source code - is a common phenomenon in software development in practice. There have been several empirical studies on the effects of cloning, but there are contradictory results regarding the connection of cloning and faults.
arxiv   +1 more source

Molecular Cloning of Sucrose Isomerase Gene and Agrobacterium-Mediated Genetic Transformation of Potato (Solanum tuberosum L.) Plants [PDF]

open access: yes, 2018
Potato (Solanum tuberosum L.) is one of the most common and important food sources on the planet, and they essential as a staple dietary item for much of the world's population. Potatoes contain carbohydrates, which lead to high blood sugar.
Soliman, H. I. (Hemaid)
core  

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

open access: yesJournal of Neuroscience, 1993
A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the current through alpha 7-channels is carried by Ca2+.
Philippe Sbgu&a   +4 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Molecular Cloning [PDF]

open access: yes, 2017
Molecular cloning is a process that manipulates the spider silk sequence to select for a proper sequence size and specific vector into which it can be expressed.
Worley, Josh
core   +1 more source

Rapid construction of mycobacterial mutagenesis vectors using ligation-independent cloning [PDF]

open access: yes, 2010
Targeted mutagenesis is one of the major tools for determining the function of a given gene and its involvement in bacterial pathogenesis. In mycobacteria, gene deletion is often accomplished by using allelic exchange techniques that commonly utilise a ...
Balhana, Ricardo   +4 more
core   +2 more sources

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1993
A neuropathological hallmark of Alzheimer disease (AD) is a widespread amyloid deposition. We analyzed the entire amino acid sequences in an amyloid preparation and found, in addition to the major beta/A4-protein (A beta) fragment, two unknown peptides ...
K. Uéda   +9 more
semanticscholar   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

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