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Evaluation of three commercial rapid immunoassays for the diagnosis of Clostridioides difficile infection [PDF]
Microbiology SpectrumCurrent guidelines recommend the use of a two-step algorithm for the laboratory diagnosis of Clostridioides difficile infection (CDI). Several commercial rapid immunoassays that detect both GDH and toxin A/B in stool samples are available and could be ...
Hannes Bjarki Vigfússon +3 more
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Extraintestinal Clostridioides difficile infection
IDCases, 2020 Clostridioides (Clostridium) difficile is the major cause of healthcare antibiotic-associated diarrhoea. However, extra-intestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI) (including bacteremia and tissue infection) are ...
Zhao Hai +6 more
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The analysis of the epidemic status and risk factors associated with different genotypes Clostridioides difficile mixed infection [PDF]
BMC MicrobiologyBackground Clostridioides difficile is the main pathogen of antibiotic-associated diarrhea and pseudomembranous enteritis. Mixed Clostridioides difficile infection are simultaneous infection of the same host with strains of different genotypes. In recent
Yulian Zhang +7 more
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Cutting edges in Clostridioides difficile infections
Swiss Medical Weekly, 2021 Clostridioides difficile is the most common cause of hospital-acquired diarrhoea and one of the most important causes of hospital-acquired infections.
Ana Durovic, Sarah Tschudin-Sutter
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Risk factors for further recurrences of Clostridioides difficile infection at the first and second recurrence: a retrospective cohort [PDF]
BMC Infectious DiseasesBackground Recurrent Clostridioides difficile infection is most effectively treated with faecal microbiota transplantation. Swedish and European guidelines suggest faecal microbiota transplantation after a first or second recurrence, respectively.
Måns Stefansson +5 more
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A Review of Therapies for Clostridioides difficile Infection [PDF]
AntibioticsClostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
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Dominance of toxigenic Clostridioides difficile strains and the appearance of the emerging PCR ribotype 955 in hospitals in Silesia, Poland [PDF]
Frontiers in MicrobiologyIntroductionToxigenic strains of Clostridioides difficile are the leading cause of healthcare-associated bacterial infections in Poland. In the Silesian Voivodeship, with 4.5 million inhabitants, the incidence of C.
Klaudia Szarek +13 more
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International Journal of Medical Microbiology, 2021 Clostridioides difficile is a Gram positive spore-forming rod and mainly responsible for nosocomial diarrhea in developed nations. Molecular and antimicrobial surveillance is important for monitoring the strain composition including genotypes of high ...
Ahmed Mohamed Mostafa Abdrabou +9 more
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Plasmids of Clostridioides difficile
Current Opinion in Microbiology, 2022 Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer. In contrast, knowledge on plasmids of the enteropathogen Clostridioides difficile is limited, and there appears to be no phenotypic consequence to carriage of many
Smits, W.K., Roseboom, A.M., Corver, J.
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Frontiers in Microbiology, 2022 The immunological response against Clostridioides difficile (C. difficile) is crucial for an improved understanding of disease mechanisms and the development of novel therapeutic strategies.
Sophie Roth +10 more
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