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A Review of Therapies for Clostridioides difficile Infection [PDF]
AntibioticsClostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
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Extraintestinal Clostridioides difficile infection
IDCases, 2020 Clostridioides (Clostridium) difficile is the major cause of healthcare antibiotic-associated diarrhoea. However, extra-intestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI) (including bacteremia and tissue infection) are ...
Zhao Hai +6 more
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Cutting edges in Clostridioides difficile infections
Swiss Medical Weekly, 2021 Clostridioides difficile is the most common cause of hospital-acquired diarrhoea and one of the most important causes of hospital-acquired infections.
Ana Durovic, Sarah Tschudin-Sutter
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Clostridioides difficile infection: an update. [PDF]
Infez MedClostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Salvati F +4 more
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The current riboswitch landscape in Clostridioides difficile. [PDF]
Microbiology (Reading)Riboswitches are 5′ RNA regulatory elements that are capable of binding to various ligands, such as small metabolites, ions and tRNAs, leading to conformational changes and affecting gene transcription or translation. They are widespread in bacteria and frequently control genes that are essential for the survival or virulence of major pathogens.
Badilla Lobo A, Soutourina O, Peltier J.
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Plasmids of Clostridioides difficile
Current Opinion in Microbiology, 2022 Plasmids are ubiquitous in the bacterial world. In many microorganisms, plasmids have been implicated in important aspects of bacterial physiology and contribute to horizontal gene transfer. In contrast, knowledge on plasmids of the enteropathogen Clostridioides difficile is limited, and there appears to be no phenotypic consequence to carriage of many
Smits, W.K., Roseboom, A.M., Corver, J.
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Frontiers in Microbiology, 2022 The immunological response against Clostridioides difficile (C. difficile) is crucial for an improved understanding of disease mechanisms and the development of novel therapeutic strategies.
Sophie Roth +10 more
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Editorial: Clostridioides difficile infection
Frontiers in MedicineGuido Granata +2 more
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Clostridioides difficile peptidoglycan modifications [PDF]
Current Opinion in Microbiology, 2022 The cortex and peptidoglycan of Clostridioides difficile have been poorly investigated. This last decade, the interest increased because these two structures are highly modified and these modifications may be involved in antimicrobial resistance. For example, C.
Héloise Coullon, Thomas Candela
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Frontiers in Immunology, 2021 BackgroundClostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale.MethodsA total of 1,160 Clostridioides ...
Jiang Li +11 more
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