Results 101 to 110 of about 32,937 (264)

Epidemiological characteristics of infections caused by bacteria Clostridioides difficile toxins [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Clostridioides difficile is one of the most common infectious agents and an important cause of infections among hospitalized patients, often resulting in severe and potentially fatal outcomes.
Koprivica Marko, Đekić-Malbaša Jelena
doaj   +1 more source

Microbiological Foundations to Optimise Intrinsic Capacity and Promote Healthy Ageing: An Integration Into the Life Course Approach

Aging Cell, EarlyView.
Gut microbiota composition may influence trajectories of intrinsic capacity throughout life. Factors that positively or negatively impact gut microbiota (determining eubiosis or dysbiosis, respectively) can affect health, potentially acting through short‐chain fatty acids and their metabolic and anti‐inflammatory functions.
Christoph Benner, Matteo Cesari, Ritu Sadana   +2 more
wiley   +1 more source

Management of Clostridioides difficile Infection [PDF]

Critical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Stephanie Quist, Renata Shamis, Christina Clarkin, Amber E. King, Bhavik M. Shah   +4 more
openaire   +3 more sources

Efficacy of bezlotoxumab in preventing the recurrence of Clostridioides difficile infection: an Italian multicenter cohort study [PDF]

, 2023
Objectives: Bezlotoxumab (BEZ) is a promising tool for preventing the recurrence of Clostridioides difficile infection (rCDI). The aim of the study was to emulate, in a real-world setting, the MODIFY trials in a cohort of participants with multiple risk ...
Barchiesi, F, Bassetti, M, Canovari, B, Cascio, A, Casolari, S, Cenderello, G, Cervo, A, Cozzi-Lepri, A, De Rosa, FG, Franceschini, E, Giacobbe, DR, Granata, G, Lorusso, C, Meschiari, M, Mussini, C, Petrosillo, N, Pinna, SM, Rogati, C, Russo, G, Tatarelli, P   +19 more
core  

The impact of the COVID‐19 pandemic on longitudinal trends of surgical mortality and inpatient quality of care in Ontario, Canada

Journal of Advanced Nursing, EarlyView.
Abstract Aims Previous studies have shown the COVID‐19 pandemic was associated with reductions in volume across a spectrum of non‐SARS‐CoV‐2 hospitalizations. In the present study, we examine the impact of the pandemic on patient safety and quality of care. Design This is a retrospective population‐based study of discharge abstracts. Methods We applied
Steven Habbous, Maggie Ford, Stacey Bar‐Ziv, Terri Donovan, Erik Hellsten   +4 more
wiley   +1 more source

Pharmacologic Management of Non‐Traumatic Dental Conditions in US Emergency Departments, 2018–2022

Journal of Public Health Dentistry, EarlyView.
ABSTRACT Objective This study examines opioid and antibiotic prescribing by United States emergency departments (EDs) for non‐traumatic dental conditions (NTDCs) between 2018 and 2022. Methods This is a secondary analysis of nationally representative ED visits using the National Hospital Ambulatory Medical Care Survey (NHAMCS) with an NTDC as the ...
Leah I. Leinbach, Xiaobai Li, Timothy Iafolla, Hosam Alraqiq   +3 more
wiley   +1 more source

Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste, Niels Christian Kyvsgaard, Mohamed Omar Ahmed, Peter Damborg, Patricia M. Dowling   +4 more
wiley   +1 more source

The Effects of Short Chain Fatty Acids on Clostridioides Difficile Growth, Sporulation, and Toxin Production [PDF]

, 2022
Short chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain important gut functions such as the intestinal barrier, signaling, and immune homeostasis.
Baldassare, Michelle
core   +1 more source

Contribution of MALDI‐TOF mass spectrometry and machine learning including deep learning techniques for the detection of virulence factors of Clostridioides difficile strains

Microbial Biotechnology
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer, Quentin Giai Gianetto, Killian Le Neindre, Valentine Latapy, Mathilda Bastide, Muriel Ehmig, Valérie Lalande, Nicolas Veziris, Alexandra Aubry, Frédéric Barbut, Catherine Eckert   +10 more
doaj   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

Neurogastroenterology &Motility, EarlyView.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source