Results 101 to 110 of about 31,246 (217)

Effect of Clostridioides difficile infection on the structure and functions of the human gut microbiota [PDF]

, 2023
Clostridioides difficile is a spore forming pathobiont that colonizes the human intestine. Germination and toxins production, most commonly occurring after use of antibiotic medications, lead to diarrhea, pseudomembranous colitis and toxic megacolon ...
DE DIEGO, LAURA
core  

From Diagnostic Challenge to Clinical Success: Rapid Multiplex PCR Identification of Cryptosporidium in HIV‐Associated Refractory Diarrhea: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Cryptosporidiosis remains a challenge in people with HIV despite its decreased incidence in developed countries. We report a case of severe diarrhea in a person with HIV where Gram stain findings prioritized cryptosporidium in the differential diagnosis.
Yudai Kono, Mayu Arase, Kohei Ukai, Keiko Soneda, Shinya Yamamoto, Kazuhiko Ikeuchi, Eisuke Adachi, Yusuke Nomura, Yoshimi Higurashi, Shinji Izumiyama, Kazuki Honjo, Yu Miyakawa, Sozaburo Ihara, Hiroyuki Abe, Mitsuhiro Fujishiro, Shu Okugawa, Takeya Tsutsumi   +16 more
wiley   +1 more source

Contribution of MALDI‐TOF mass spectrometry and machine learning including deep learning techniques for the detection of virulence factors of Clostridioides difficile strains

Microbial Biotechnology
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer, Quentin Giai Gianetto, Killian Le Neindre, Valentine Latapy, Mathilda Bastide, Muriel Ehmig, Valérie Lalande, Nicolas Veziris, Alexandra Aubry, Frédéric Barbut, Catherine Eckert   +10 more
doaj   +1 more source

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

The persistence landscape and some of its properties

, 2019
Persistence landscapes map persistence diagrams into a function space, which may often be taken to be a Banach space or even a Hilbert space. In the latter case, it is a feature map and there is an associated kernel. The main advantage of this summary is
A Adcock, A Collins, A Robinson, A Zomorodian, AJ Blumberg, B Bollobás, B Di Fabio, D Cohen-Steiner, E Munch, F Chazal, F Chazal, H Adams, H Edelsbrunner, I Donato, K Turner, K Turner, M Carrière, M Gameiro, M Gidea, M Lesnick, P Bendich, P Bubenik, P Bubenik, P Bubenik, P Bubenik, P Dłotko, RJ Adler, S Kališnik, V Kovacev-Nikolic, V Patrangenaru, V Robins, Y Lee, Y Wang, Y Wang   +33 more
core   +1 more source

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

ChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee, Dingran Chang, Jimmy Gu, Bruno J. Salena, Yingfu Li   +4 more
wiley   +1 more source

The microbiome research in obstetrics and gynecology is getting attention—Some reasons why

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Hana Shabana, Kenny A. Rodriguez‐Wallberg   +1 more
wiley   +1 more source

Lachnospiraceae‐Derived Extracellular Vesicles Mediate the Cardioprotective Effects of Barley Leaf in Myocardial Infarction by Improving Intestinal Stem Cell Function

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Ischaemic cardiovascular diseases, particularly myocardial infarction (MI), remain the leading causes of morbidity and mortality worldwide. Targeting extracellular vesicles (EVs) from the gut microbiota by diet may provide opportunities to improve cardiovascular health. Barley leaf (BL) has a long history of use in Traditional Chinese medicine
Wenjing Chen, Yifan Zhao, Qian Zhao, Yingzhuo Zhou, Chen Ma, Li Dong, Yinghua Luo, Zhong Zhang, Fang Chen, Xiaosong Hu, Daotong Li   +10 more
wiley   +1 more source

Push Enteroscopic Jejunal and Ileoscopic Delivery of Fecomicrobiota Transplantation (FMT) for Treatment of Clostridioides difficile Enteritis in a Patient With a Total Colectomy and Ileal Pouch‐Anal Anastomosis (IPAA): A Case Report

JGH Open, Volume 10, Issue 3, March 2026.
ABSTRACT Clostridioides difficile infection (CDI) is recognized as the leading cause of antibiotic‐associated diarrhea. There are several case reports of C. difficile enteritis in patients who have undergone colectomy and end ileostomy or ileal pouch‐anal anastomosis. This case report describes a unique case of recurrent C.
Zoe Tan, Edward Young, Arvind Rajagopalan   +2 more
wiley   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source