Results 111 to 120 of about 31,421 (293)

Management of Clostridioides difficile Infection [PDF]

Critical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Stephanie Quist, Renata Shamis, Christina Clarkin, Amber E. King, Bhavik M. Shah   +4 more
openaire   +3 more sources

Efficacy of bezlotoxumab in preventing the recurrence of Clostridioides difficile infection: an Italian multicenter cohort study [PDF]

, 2023
Objectives: Bezlotoxumab (BEZ) is a promising tool for preventing the recurrence of Clostridioides difficile infection (rCDI). The aim of the study was to emulate, in a real-world setting, the MODIFY trials in a cohort of participants with multiple risk ...
Barchiesi, F, Bassetti, M, Canovari, B, Cascio, A, Casolari, S, Cenderello, G, Cervo, A, Cozzi-Lepri, A, De Rosa, FG, Franceschini, E, Giacobbe, DR, Granata, G, Lorusso, C, Meschiari, M, Mussini, C, Petrosillo, N, Pinna, SM, Rogati, C, Russo, G, Tatarelli, P   +19 more
core  

Some simple rules for estimating reproduction numbers in the presence of reservoir exposure or imported cases [PDF]

arXiv, 2018
The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to derive simple rules for the basic reproduction number for populations with local person-to-person transmission and
arxiv  

Hospital Infection Control: Clostridioides difficile

Clinics in Colon and Rectal Surgery, 2020
Abstract Clostridioides difficile remains a leading cause of healthcare-associated infection. Efforts at C. difficile prevention have been hampered by an increasingly complex understanding of transmission patterns and a high degree of heterogeneity among existing studies. Effective prevention of C.
Nicholas A Turner, Nicholas A Turner, Deverick J. Anderson, Deverick J. Anderson   +3 more
openaire   +4 more sources

Impact of sulfonamide allergy label on clinical outcomes of acute cystitis: a retrospective matched cohort study

Internal Medicine Journal, EarlyView.
Abstract Background Cystitis is a common infection in an otherwise healthy individual. Sulfonamide antibiotics are first‐line treatment options. Sulfonamide allergy label (SAL) is the second most common antibiotic allergy label in electronic health records, yet its impact on clinical outcomes in patients with cystitis is not well‐characterised.
Ray Moussa, Tyler Miluski, Gisoo Ghaffari, Taha Al‐Shaikhly   +3 more
wiley   +1 more source

The Effects of Short Chain Fatty Acids on Clostridioides Difficile Growth, Sporulation, and Toxin Production [PDF]

, 2022
Short chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain important gut functions such as the intestinal barrier, signaling, and immune homeostasis.
Baldassare, Michelle
core   +1 more source

Fluid fragmentation from hospital toilets [PDF]

arXiv, 2013
Hospital-acquired infections represent significant health and financial burdens to society. Clostridium difficile (C. difficile) is a particularly challenging bacteria with the potential to cause severe diarrhea and death. One mode of transmission for C.
arxiv  

The impact of the COVID‐19 pandemic on longitudinal trends of surgical mortality and inpatient quality of care in Ontario, Canada

Journal of Advanced Nursing, EarlyView.
Abstract Aims Previous studies have shown the COVID‐19 pandemic was associated with reductions in volume across a spectrum of non‐SARS‐CoV‐2 hospitalizations. In the present study, we examine the impact of the pandemic on patient safety and quality of care. Design This is a retrospective population‐based study of discharge abstracts. Methods We applied
Steven Habbous, Maggie Ford, Stacey Bar‐Ziv, Terri Donovan, Erik Hellsten   +4 more
wiley   +1 more source

РОЗРОБКА CЕЛЕКТИВНОГО СЕРЕДОВИЩА ДЛЯ ВИДІЛЕННЯ ТОКСИН ПРОДУКУЮЧИХ ШТАМІВ C. DIFFICILE [PDF]

, 2020
Enterocolitis disorders caused by Clostridioides difficile infection still remain a serious health problem in the world. In many countries CDI is officially considered a nosocomial infection that causes considerable economic losses, including diagnostic ...
Kheder, Said
core   +2 more sources

Contribution of MALDI‐TOF mass spectrometry and machine learning including deep learning techniques for the detection of virulence factors of Clostridioides difficile strains

Microbial Biotechnology
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer, Quentin Giai Gianetto, Killian Le Neindre, Valentine Latapy, Mathilda Bastide, Muriel Ehmig, Valérie Lalande, Nicolas Veziris, Alexandra Aubry, Frédéric Barbut, Catherine Eckert   +10 more
doaj   +1 more source