Results 121 to 130 of about 32,937 (264)

Treatment of Clostridioides Difficile with Fecal Microbiota Transplantation [PDF]

, 2020
Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening ...
Green, Brenton
core   +2 more sources

Consortium of Probiotics Attenuates Colonization of Clostridioides difficile

Frontiers in Microbiology, 2019
Clostridioides difficile infection (CDI) is increasing morbidity and mortality rates globally. Fecal microbiota transplantation (FMT), an effective therapy for eliminating Clostridioides difficile (C.
Xianping Li, Xianping Li, Qiongfang Chu, Qiongfang Chu, Qiongfang Chu, Yuanming Huang, Yuanming Huang, Yuchun Xiao, Yuchun Xiao, Liqiong Song, Liqiong Song, Siyi Zhu, Siyi Zhu, Ying Kang, Ying Kang, Shan Lu, Shan Lu, Jianguo Xu, Jianguo Xu, Zhihong Ren, Zhihong Ren   +20 more
doaj   +1 more source

The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses

MicrobiologyOpen, 2020
Clostridioides difficile infection (CDI) represents an important health problem worldwide, with significant morbidity and mortality. This infection has also high recurrence rates, whose pathophysiological grounds are still poorly understood. Based on our
Gabrio Bassotti, Andrea Marchegiani, Pierfrancesco Marconi, Katia Fettucciari   +3 more
doaj   +1 more source

Repurposing auranofin as a Clostridioides difficile therapeutic

Journal of Antimicrobial Chemotherapy, 2019
Abstract Background Clostridioides difficile (previously Clostridium difficile) is the leading cause of nosocomial, antibiotic-associated diarrhoea worldwide. Currently, the gold standard of treatment for C.
Havva Pehlivanoglu, Dena Lyras, Meagan L. James, Melanie J. Thomson, Melanie L. Hutton, Callum J. Vidor   +5 more
openaire   +3 more sources

Impact of a training program on the surveillance of Clostridioides difficile infection [PDF]

, 2019
A high degree of vigilance and appropriate diagnostic methods are required to detect Clostridioides difficile infection (CDI). We studied the effectiveness of a multimodal training program for improving CDI surveillance and prevention.
Bella, F., Freixas, N., Gudiol, F., Hornero, A., Limon, E., Pujol, M., Pérez, J., Sopena, Nieves, Universitat Autònoma de Barcelona   +8 more
core   +1 more source

Real-world Effectiveness of Fecal Microbiota Transplantation for First or Second Clostridioides difficile Infection [PDF]

Background & Aims: Clostridioides difficile infection (CDI) is associated with high mortality. Fecal microbiota transplantation (FMT) is an established treatment for recurrent CDI, but its use for first or second CDI remains experimental. We aimed to
Baumwall, Simon Mark Dahl, Birn, Frederik Hyllested, Dahlerup, Jens Frederik, Erikstrup, Christian, Erikstrup, Lise Tornvig, Fernis, Christa Marie Culmbach, Glerup, Henning, Grosen, Anne Karmisholt, Hansen, Mette Mejlby, Helms, Morten, Hvas, Christian Lodberg, Kelsen, Jens, Krarup, Anne Lund, Lødrup, Anders Bergh, Mikkelsen, Susan, Neumann, Anders, Paaske, Sara Ellegaard, Rubak, Tone, Rågård, Nina, Svenningsen, Lise, Vinter-Jensen, Lars   +20 more
core   +1 more source

Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway [PDF]

, 2018
Tanya Monaghan, Benjamin H. Mullish, Jordan Patterson, Gane Ka‐Shu Wong, Julian R. Marchesi, Huiping Xu, Tahseen Jilani, Dina Kao   +7 more
openalex   +1 more source

Curbing inappropriate C. difficile treatment in patients receiving concomitant laxatives

Antimicrobial Stewardship & Healthcare Epidemiology
In the setting of universal Clostridioides difficile screening, we implemented an alert that triggered when C. difficile treatment was ordered in patients who recently received laxatives. This resulted in C.
Paige Fields, Christopher David, Anish Choksi, Natasha N. Pettit, Alison K. Lew, Jennifer Pisano, Cynthia T. Nguyen   +6 more
doaj   +1 more source

Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile Species [PDF]

, 2018
Louis‐Charles Fortier
openalex   +1 more source

Reduction in Health Care Facility–Onset Clostridioides difficile Infection: A Quality Improvement Initiative

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021
Objective: To reduce health care facility–onset (HCFO) Clostridioides difficile infection (CDI) incidence by improving diagnostic stewardship and reducing the inappropriate testing of C difficile assays.
Himesh B. Zaver, MD, Varun P. Moktan, MD, Eugene P. Harper, MD, Aman Bali, MD, Ayan Nasir, MD, Carla Foulks, MD, Justin Kuhlman, MD, Max Green, MD, Gillian A. Algan, BS, Heather C. Parth, MPH, Melody Wu-Ballis, BS, Sandra DiCicco, BS, Brenda T. Smith, BS, Ronald N. Owen, BS, Lorraine S. Mai, BS, Sarah L. Spiros, BS, John Griffis, BS, Daphne T. Ramsey Walker, BS, D. Jane Hata, PhD, Justin M. Oring, DO, Harry R. Powers, MD, Wendelyn Bosch, MD   +21 more
doaj