Clostridioides difficile Infection [PDF]
Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Guh, Preeta K. Kutty
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Pathogenicity and virulence of Clostridioides difficile
Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of recurrence, morbidity, and mortality. Treatment is complex, since antibiotics constitute both the main treatment and the major risk factor for infection.
Jessica E. Buddle, Robert P. Fagan
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Diagnosing Clostridioides difficile infections with molecular diagnostics: multicenter evaluation of revogene C. difficile assay [PDF]
Clostridioides difficile infections are a significant threat to our healthcare system, and rapid and accurate diagnostics are crucial to implement the necessary infection prevention and control measurements.
Altwegg M.+16 more
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Clostridioides (Clostridium) difficile
Abstract Clostridioides difficile (formerly Clostridium) causes a potentially life-threatening diarrhoea, which is acquired predominantly in hospitals. The incidence of infections caused by this organism has increased markedly over the past 20 years, although the incidence has fallen in the UK since a peak about 10 years ago.
Tim Planche, Martina Cusinato
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Abstract Background We reviewed the scientific literature to gain insight on the epidemiology and outcome of Strongyloides stercoralis infections after transplantation. Methods CINAHL, PUBMED, and OVID/MEDLINE were reviewed from inception through March 31, 2022 using key words Strongyloides and transplantation.
Cybele Lara R. Abad+3 more
wiley +1 more source
Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network [PDF]
Clostridioides difficile infection is widespread throughout countries and represents an important cause of nosocomial diarrhoea, with relatively high morbidity.
Bassotti, Gabrio+4 more
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Clostridioides difficile epidemiology in India
Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan+4 more
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Effect of fecal microbiota, live-jslm (REBYOTA [RBL]) on health-related quality of life in patients with recurrent Clostridioides difficile infection: Results from the PUNCH CD3 clinical trial [PDF]
BACKGROUND: Recurrence of METHODS: This was a secondary analysis of a randomized, double-blind, placebo-controlled phase 3 study (PUNCH CD3). The disease-specific RESULTS: Findings were analyzed in a total of 185 patients (RBL, n = 128 [69.2%]; placebo ...
Bancke, Lindy L+10 more
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Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12
Kathryn A Connor, Kelly M Conn
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Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) [PDF]
Indexación: Scopus.In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant anaerobic
Angelica Reyes-Jara+14 more
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