Results 31 to 40 of about 23,676 (213)

Novel Drivers of Virulence in Clostridioides difficile Identified via Context-Specific Metabolic Network Analysis

open access: yesmSystems, 2021
Clostridioides difficileC ...
Matthew L. Jenior   +8 more
doaj   +1 more source

Gut Microbiota Diversity of Preterm Neonates Is Associated With Clostridioides Difficile Colonization

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
In adults, Clostridioides difficile infections are associated with alterations of the intestinal bacterial populations. Although preterm neonates (PN) are frequently colonized by C. difficile, limited data are available regarding the relationship between
Jeanne Couturier   +13 more
doaj   +1 more source

Epidemiology of Clostridioides difficile in South Africa

open access: yesPLOS ONE, 2021
Background Clostridioides difficile (CD) is the most common healthcare-associated enteric infection. There is currently limited epidemiological evidence on CD incidence in South Africa. Aim To estimate the burden of CD infection (CDI) in the South African public sector between 1 July 2016 and 30 June 2017.
Pieter de Jager   +4 more
openaire   +5 more sources

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

open access: yesInfectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich   +15 more
doaj   +1 more source

Evaluation of three commercial rapid immunoassays for the diagnosis of Clostridioides difficile infection

open access: yesMicrobiology Spectrum
Current guidelines recommend the use of a two-step algorithm for the laboratory diagnosis of Clostridioides difficile infection (CDI). Several commercial rapid immunoassays that detect both GDH and toxin A/B in stool samples are available and could be ...
Hannes Bjarki Vigfússon   +3 more
doaj   +1 more source

Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis

open access: yesAntibiotics, 2019
Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu   +3 more
doaj   +1 more source

The repertoire of ABC proteins in Clostridioides difficile

open access: yesComputational and Structural Biotechnology Journal, 2021
ATP-binding cassette (ABC) transporters belong to one of the largest membrane protein superfamilies, which function in translocating substrates across biological membranes using energy from ATP hydrolysis. Currently, the classification of ABC transporters in Clostridioides difficile is not complete.
Matthew Phanchana   +6 more
openaire   +4 more sources

Uncovering the Harms of Treating Clostridioides difficile Colonization

open access: yesmSphere, 2021
Patients with toxin-negative Clostridioides ...
Christopher R. Polage   +1 more
doaj   +1 more source

Clostridioides difficile Flagella

open access: yesInternational Journal of Molecular Sciences
Clostridioides difficile is an important pathogen for humans with a lead in nosocomial infection, but it is also more and more common in communities. Our knowledge of the pathology has historically been focused on the toxins produced by the bacteria that remain its major virulence factors.
Jean-Christophe Marvaud   +3 more
openaire   +2 more sources

Prospective Review of Clostridioides difficile Testing Indications to Inform Local Laboratory Stewardship Initiatives

open access: yesInfection Prevention in Practice, 2019
Summary: We conducted a prospective chart review to determine the prevalence of and reasons for inappropriate Clostridioides difficile test-ordering at a tertiary care hospital. Inappropriate orders accounted for 54% of all tests.
Noah Reich   +7 more
doaj   +1 more source

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