Clostridioides difficile epidemiology in India
Anaerobe, 2022 Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in low-and-middle-income countries (LMICs) such as India,
Tanya M. Monaghan +4 more
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Nature Communications, 2022 Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh +7 more
doaj +1 more source
Microbiology Spectrum, 2021 Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale +4 more
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Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) [PDF]
, 2018 Indexación: Scopus.In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant anaerobic
Angelica Reyes-Jara +14 more
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Agricultural fertilization with poultry manure results in persistent environmental contamination with the pathogen Clostridioides difficile [PDF]
, 2021 During a field experiment applying broiler manure for fertilization of agricultural land, we detected viable Clostridioides (also known as Clostridium) difficile in broiler faeces, manure, dust and fertilized soil.
Amon, Thomas +9 more
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High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
, 2019 Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
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Dogs as carriers of virulent and resistant genotypes of Clostridioides difficile [PDF]
, 2022 While previous research on zoonotic transmission of community-acquired Clostridioides difficile infection (CA-CDI) focused on food-producing animals, the present study aimed to investigate whether dogs are carriers of resistant and/or virulent C ...
Allerberger, F. +15 more
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Pathogenicity and virulence of Clostridioides difficile
Virulence, 2023 Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of recurrence, morbidity, and mortality. Treatment is complex, since antibiotics constitute both the main treatment and the major risk factor for infection.
Jessica E. Buddle, Robert P. Fagan
openaire +3 more sources
Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults
SAGE Open Medicine, 2020 Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12
Kathryn A Connor, Kelly M Conn
doaj +1 more source
Applications of Fecal Microbiota Transplantation: Emphasis on Clostridioides difficile Infections [PDF]
, 2022 Objective: This study aimed to perform a comprehensive review of clinical trials using fecal microbiota transplantation in cases of Clostridioides difficile infection.
Longo, Priscila Larcher +3 more
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