Results 41 to 50 of about 25,087 (168)

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Case report of two patients with recurrent watery stools following prophylactic ileostomy reversal after rectal cancer surgery

结直肠肛门外科
The causes of diarrhea after enterostomy reversal may be related to surgical treatment, and its severity varies. Clinical interventions are often based on the patient’s symptomatic presentation.
Shen Shuai, Gao Hui
doaj   +1 more source

Edoxaban‐induced enterocolitis: The first case report demonstrating distinct endoscopic and histological features

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Direct oral anticoagulants (DOACs), including edoxaban, are widely used for stroke prevention in atrial fibrillation and venous thromboembolism. While gastrointestinal bleeding and diarrhea are recognized adverse effects, DOAC‐induced enterocolitis has not been established as a distinct clinical entity.
Katsuya Endo, Jun Yamada, Tomofumi Katayama, Yuki Yoshino, Daisuke Fukushi, Akinobu Koiwai, Takayuki Kogure, Morihisa Hirota, Kennichi Satoh   +8 more
wiley   +1 more source

Severe Gastroduodenitis Associated With Ulcerative Colitis After Total Colectomy Successfully Treated With Endoscopic Hemostasis and Oral Tacrolimus

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Herein, we report a rare case of gastroduodenitis associated with ulcerative colitis (UC). A 42‐year‐old man was diagnosed with UC 1 year prior to admission to our hospital. The patient underwent a 3‐stage total colectomy and ileal pouch‐anal anastomosis for severe UC.
Koji Fujimoto, Shuhei Hosomi, Yumie Kobayashi, Rieko Nakata, Yu Nishida, Fumio Tanaka, Yasuhiro Fujiwara   +6 more
wiley   +1 more source

Gut microbiome and plasma lipidome analysis reveals a specific impact of Clostridioides difficile infection on intestinal bacterial communities and sterol metabolism [PDF]

, 2023
Ricardo M. Arcay, Maria Barceló‐Nicolau, Loreto Suárez-Bode, Luisa Martı́n, Rebeca Reigada, Marcus Höring, Gerhard Liebisch, Carmen Garrido, Gabriel Cabot, Helem Vílchez, Carla López-Causapé, Antonio Oliver, Gwendolyn Barceló‐Coblijn, A. Mena   +13 more
openalex   +1 more source

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano, Valerio Voglino, Federico Beati, Cristina Martucci, Chiara Grimaldi, Francesca Del Bufalo, Annalisa Serra, Francesco Fabozzi, Carmen Malaspina, Pier Luigi Di Paolo, Gian Luigi Natali, Simone Reali, Maria Antonietta De Ioris, Alessandro Crocoli   +13 more
wiley   +1 more source

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella, Sudeep Sarma, Caroline M. Hinesley, Corey E. Febo, Keith A. Breau, Deniz Durmusoglu, Ethan Purnell, Scott T. Magness, Carol K. Hall, Stefano Menegatti, Nathan Crook   +10 more
wiley   +1 more source

Knowledge, Attitude, and the Practice in Nosocomial Infection Control Among Afghan Healthcare Workers in Herat Afghanistan: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Hospital‐acquired infections (HIAs) remain a major threat to patient and healthcare worker (HCW) safety globally, with higher burden in low‐resource settings. Despite moderate knowledge among HCWs in many low‐income contexts, actual adherence to infection prevention practices is often poor.
Mohammad Masudi, Enayatollah Ejaz, Mohammad Faisal Wardak, Ali Rahimi, Nasar Ahmad Shayan, Joseph Christian Obnial, Don Eliseo Lucero‐Prisno III   +6 more
wiley   +1 more source

A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari, Setare Abolghasemi, Elham Khanniri, Maryam Bayanati, Rahil Hakimimofrad, Mohammad Mahboubi‐Rabbani   +5 more
wiley   +1 more source