Results 71 to 80 of about 25,087 (168)

Pathogenicity locus determinants and toxinotyping of Clostridioides difficile isolates recovered from Iranian patients

open access: yesNew Microbes and New Infections, 2018
Little is known about the toxin profiles, toxinotypes and variations of toxin Clostridioides difficile C (tcdC) in Iranian C. difficile isolates. A total of 818 stool specimens were obtained from outpatients (n = 45) and hospitalized patients (n = 773 ...
A. Aliramezani   +13 more
doaj   +1 more source

Incidence of healthcare-associated Clostridioides difficile infection in a quaternary referral university hospital in Brazil

open access: bronze, 2022
Daniela S. Braga   +8 more
openalex   +2 more sources

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

open access: yesCell Reports
Summary: The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are receptors that are exploited by Clostridioides difficile toxin B (TcdB), the major virulence factor responsible for pathogenesis associated with ...
Julia Kinsolving   +10 more
doaj   +1 more source

Curbing inappropriate C. difficile treatment in patients receiving concomitant laxatives

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
In the setting of universal Clostridioides difficile screening, we implemented an alert that triggered when C. difficile treatment was ordered in patients who recently received laxatives. This resulted in C.
Paige Fields   +6 more
doaj   +1 more source

1985. Impact of Suppressing Ciprofloxacin Susceptibility Results on Antibiotic Utilization and Hospital-acquired Clostridioides difficile Infection [PDF]

open access: gold, 2019
Bryan P. White   +5 more
openalex   +1 more source

Effects of defined gut microbial ecosystem components on virulence determinants of Clostridioides difficile [PDF]

open access: gold, 2019
Christian Carlucci   +9 more
openalex   +1 more source

A Review of Therapies for Clostridioides difficile Infection

open access: yesAntibiotics
Clostridioides difficile is an urgent public health threat that affects approximately half a million patients annually in the United States. Despite concerted efforts aimed at the prevention of Clostridioides difficile infection (CDI), it remains a ...
Faiza Morado, Neha Nanda
doaj   +1 more source

Plasmid-mediated metronidazole resistance in Clostridioides difficile [PDF]

open access: gold, 2020
Ilse M. Boekhoud   +9 more
openalex   +1 more source

Characterization of Non-Toxigenic Clostridioides difficile Strains Isolated from Preterm Neonates and In Vivo Study of Their Protective Effect [PDF]

open access: gold, 2020
Jeanne Couturier   +9 more
openalex   +1 more source

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