Results 71 to 80 of about 24,553 (208)

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source

Clostridioides difficile Infection

Clinics in Colon and Rectal Surgery, 2020
Linda, Ferrari, Alessandro, Fichera
openaire   +5 more sources

Contribution of MALDI‐TOF mass spectrometry and machine learning including deep learning techniques for the detection of virulence factors of Clostridioides difficile strains

Microbial Biotechnology
Clostridioides difficile (CD) infections are defined by toxins A (TcdA) and B (TcdB) along with the binary toxin (CDT). The emergence of the ‘hypervirulent’ (Hv) strain PR 027, along with PR 176 and 181, two decades ago, reshaped CD infection ...
Alexandre Godmer, Quentin Giai Gianetto, Killian Le Neindre, Valentine Latapy, Mathilda Bastide, Muriel Ehmig, Valérie Lalande, Nicolas Veziris, Alexandra Aubry, Frédéric Barbut, Catherine Eckert   +10 more
doaj   +1 more source

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Frontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen, Xue Liu, Kai Wan, Hong Liu, Cheng Zhang, Xi Zhang, Qin Wen   +6 more
doaj   +1 more source

MALDI-TOF MS: An alternative approach for ribotyping Clostridioides difficile isolates in Brazil [PDF]

, 2021
Leandro Gouveia Carneiro, Tatiana Castro Abreu Pinto, Hércules Moura, John R. Barr, Regina Maria Cavalcanti Pilotto Domingues, Eliane de Oliveira Ferreira   +5 more
openalex   +1 more source

Clostridioides difficile infection: an update

Infezioni in Medicina
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Federica, Salvati, Francesca, Catania, Rita, Murri, Massimo, Fantoni, Carlo, Torti   +4 more
openaire   +2 more sources

Clostridioides difficile Infection

RGUHS Journal of Medical Sciences, 2022
In the past decade Clostrdioides difficile has become a leading enteric pathogen causing antibiotic-associated diarrohoea and colitis. The manifestations range from diarrhoea to life-threatening damage to the large intestine. It is noted as a nosocomial and community acquired infection in most of the countries including India.
openaire   +1 more source

The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties

, 2022
Andrew E. Clark, Chelsea C. Adamson, Katelyn E. Carothers, Bryan Angelo P. Roxas, V. K. Viswanathan, Gayatri Vedantam   +5 more
openalex   +1 more source

A Computational Framework to Quantify Host-Microbiome Interactions in Clostridioides Difficile Infection [PDF]

, 2020
Shanlin Ke, Nira R. Pollock, Wang Xu-wen, Xinhua Chen, Kaitlyn Daugherty, Qianyun Lin, Hua Xu, Kevin W. Garey, Anne J Gonzales-Luna, Yang‐Yu Liu, Ciarán P. Kelly   +10 more
openalex   +1 more source

The role of hospital environment and the hands of medical staff in the transmission of the Clostridioides (Clostridium) difficile infection

Medycyna Pracy, 2019
This paper attempts to determine the role of the hospital environment in the spread of Clostridioides/Clostridium (C.) difficile infections based on a review of studies published in the medical literature and in the light of the authors’ own ...
Monika Kabała, Małgorzata Aptekorz, Gajane Martirosian   +2 more
doaj   +1 more source