Results 71 to 80 of about 23,676 (213)

The impact of the COVID‐19 pandemic on longitudinal trends of surgical mortality and inpatient quality of care in Ontario, Canada

open access: yesJournal of Advanced Nursing, Volume 81, Issue 11, Page 7556-7570, November 2025.
Abstract Aims Previous studies have shown the COVID‐19 pandemic was associated with reductions in volume across a spectrum of non‐SARS‐CoV‐2 hospitalizations. In the present study, we examine the impact of the pandemic on patient safety and quality of care. Design This is a retrospective population‐based study of discharge abstracts. Methods We applied
Steven Habbous   +4 more
wiley   +1 more source

Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany

open access: yesAntimicrobial Resistance and Infection Control
Background Clostridioides difficile infections (CDI) present significant health risks and are among the most important nosocomial infections. Ribotype (RT) 027 poses a particular risk due to its proposed “hypervirulence”. Traditionally, C.
Esther E. Dirks   +9 more
doaj   +1 more source

The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia

open access: yesZoonoses and Public Health, Volume 72, Issue 7, Page 587-611, November 2025.
ABSTRACT As the climate of Asia changes under the influence of global warming, the incidence and spatial distribution of known zoonoses will evolve, and new zoonoses are expected to emerge as a result of greater exposure to organisms which currently occur only in wildlife.
Roger S. Morris, Masako Wada
wiley   +1 more source

Quantification of Clostridioides (Clostridium) difficile in feces of calves of different age and determination of predominant Clostridioides difficile ribotype 033 relatedness and transmission between family dairy farms using multilocus variable-number tandem-repeat analysis

open access: yesBMC Veterinary Research, 2018
Background Community acquired Clostridioides (Clostridium) difficile infection (CA-CDI) is a significant health problem in human and veterinary medicine. Animals are often considered as potential reservoirs for CA-CDI.
Petra Bandelj   +6 more
doaj   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao   +17 more
wiley   +1 more source

Half‐Pipe Melt Electrowritten Scaffolds Support Engineering of an Immunocompetent Hydrogel‐Embedded Intestine‐on‐a‐Chip

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
The immunocompetent Intestine‐on‐a‐Chip (IoC) is developed using melt electrowritten (MEW) half‐pipes. Intestinal epithelial cell (IEC) culture is optimized in the MEW‐based IoC, followed by co‐culture with monocyte‐derived dendritic cells (moDCs) and T cells in 3D hydrogels.
Robine Janssen   +10 more
wiley   +1 more source

Targeting gut microbiota and metabolites in cancer radiotherapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma   +6 more
wiley   +1 more source

Epidemiological characteristics of infections caused by bacteria Clostridioides difficile toxins [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. Clostridioides difficile is one of the most common infectious agents and an important cause of infections among hospitalized patients, often resulting in severe and potentially fatal outcomes.
Koprivica Marko, Đekić-Malbaša Jelena
doaj   +1 more source

Phenotypic and Genetic Characterization and Production Abilities of Lacticaseibacillus rhamnosus Strain 484—A New Probiotic Strain Isolated From Human Breast Milk

open access: yesFood Science &Nutrition, Volume 13, Issue 10, October 2025.
Human breast milk (HBM) is a recognized source of probiotic bacteria, with species such as Lacticaseibacillus rhamnosus demonstrating considerable potential for applications in both the medical and food industries. In this study, the probiotic potential of strain 484, isolated from HBM, was evaluated through comprehensive phenotypic and genetic ...
Natalia Czarnecka   +5 more
wiley   +1 more source

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