Results 71 to 80 of about 234,636 (297)

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Tali Eviatar   +35 more
wiley   +1 more source

DEVELOPMENT OF PCR KITS FOR BACTERIA OF THE GENUS CLOSTRIDIUM AND TOXINOTYPES CL. PERFRINGENS IDENTIFICATION

open access: yesSiberian Journal of Life Sciences and Agriculture
Bovine clostridiosis is one of the major problems in veterinary medicine, animal husbandry and food safety. Clostridia cause zoonotic infectious diseases.
Natalia A. Bezborodova   +5 more
doaj   +1 more source

Volumetric mass transfer and dilution rate as key parameters for sustainable industrial syngas fermentation to isopropyl alcohol: modeling and parametric assessment

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Synthesis gas fermentation is a promising route for the valorization of steel mill off‐gas and for replacing conventional fossil‐based isopropyl alcohol (IPA) production. A recent 120 L pilot‐scale study reported 85% gas conversion at 90% product selectivity and claimed a negative global warming potential (GWP) without detailed process design.
Gijs J. A. Brouwer   +3 more
wiley   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen   +4 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Engineering of 2‐ketoacid Decarboxylases for Production of Isobutanol and Other Fusel Alcohols in Saccharomyces cerevisiae

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich   +6 more
wiley   +1 more source

Clinical signs and post-mortem lesions caused by clostridial enterotoxemia in rabbits

open access: yesВетеринария сегодня
Enterotoxemia, accompanied by diarrhea and bloating, is still a matter of pressing concern to the rabbit farming. Clostridia bacteria are often isolated from the internal organs of rabbits that have died of an anaerobic infection.
A. S. Metleva   +2 more
doaj   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

Vaccine Production to Protect Animals Against Pathogenic Clostridia

open access: yesToxins, 2019
Clostridium is a broad genus of anaerobic, spore-forming, rod-shaped, Gram-positive bacteria that can be found in different environments all around the world.
Nicolas E. Zaragoza   +4 more
doaj   +1 more source

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