Results 71 to 80 of about 359,464 (292)

In vitro and in vivo characterization of Clostridium scindens bile acid transformations

Gut Microbes, 2019
The human gut hosts trillions of microorganisms that exert a profound influence on human biology. Gut bacteria communicate with their host by secreting small molecules that can signal to distant organs in the body.
Solenne Marion, Nicolas Studer, Lyne Desharnais, Laure Menin, Stéphane Escrig, Anders Meibom, Siegfried Hapfelmeier, Rizlan Bernier-Latmani   +7 more
doaj   +1 more source

A case of gas gangrene with fatal outcome (gas gangrene: A case report) [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Introduction: The clinical course of gas gangrene is often rapidly progressive, with a fatal outcome in up to 80% of treated cases. The disease is most commonly a consequence of trauma or surgical interventions.
Pavić Slađana, Slović Radomir, Novković Aleksa, Pavić Aleksandra   +3 more
doaj   +1 more source

Faecal microbiota transplantation : a regulatory hurdle? [PDF]

, 2017
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart, Janssens, Yorick, Verbeke, Frederick, Wynendaele, Evelien   +3 more
core   +2 more sources

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

Advanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan   +6 more
wiley   +1 more source

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Gut Microbes, 2020
The formation of secondary bile acids by gut microbes is a current topic of considerable biomedical interest. However, a detailed understanding of the biology of anaerobic bacteria in the genus Clostridium that are capable of generating secondary bile ...
Jason M. Ridlon, Saravanan Devendran, João Mp Alves, Heidi Doden, Patricia G. Wolf, Gabriel V. Pereira, Lindsey Ly, Alyssa Volland, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, George E. Chlipala, Stefan J. Green, Alvaro G. Hernandez, Christopher J. Fields, Christy L. Wright, Genta Kakiyama, Isaac Cann, Purna Kashyap, Vance McCracken, H. Rex Gaskins   +21 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Comparison of the Hospital-Acquired Clostridium difficile Infection Risk of Using Proton Pump Inhibitors versus Histamine-2 Receptor Antagonists for Prophylaxis and Treatment of Stress Ulcers: A Systematic Review and Meta-Analysis

Gut and Liver, 2017
Background/AimsAlthough proton pump inhibitors (PPIs) have been widely used for the prevention and treatment of stress gastric ulcers in hospital settings, there are concerns that PPIs increase the risk of Clostridium difficile infection (CDI).
Mohamed Azab, Loomee Doo, Daniel H. Doo, Yousif Elmofti, Muazer Ahmed, John Jay Cadavona, Xibei B. Liu, Amaan Shafi, Moon Kyung Joo, Ji Won Yoo   +9 more
doaj   +1 more source

Production of butanol by fermentation in the presence of cocultures of clostridium [PDF]

, 1985
Sugars are converted to a mixture of solvents including butanol by a fermentation process employing a coculture of microorganisms of the Clostridium genus, one of said microorganisms favoring the production of butyric acid and the other of which converts
Bergstrom, S. L., Foutch, G. L.
core   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

Advanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena, Estelle Morvan, Clara Lambert, Anagha Kallisseri Parambil, Martin Lefeuvre, Zeren Xu, Nadia El Mammeri, Florian Malard, Erick J. Dufourc, Cécile Feuillie, Christophe Grangeasse, Birgit Habenstein   +11 more
wiley   +1 more source

MICROBIOLOGÍA DE LA PRODUCCIÓN CONTROLADA DE SULFURO DE HIDRÓGENO. UNA EXPERIENCIA DE TRABAJO EN EL LABORATORIO DE EDUCACIÓN SECUNDARIA

Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2010
Esta comunicación muestra las directrices para lograr el éxito en la producción microbiológica de sulfuro de hidrógeno (a microescala), como experiencia en el laboratorio de educación secundaria obligatoria, el estudio de su metabolismo y las ...
J.P. López Pérez, J.J. Jiménez, A. Fabregat, J.A. Gutiérrez   +3 more
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