Base editing enables duplex point mutagenesis in Clostridium autoethanogenum at the price of numerous off-target mutations [PDF]
Base editors are recent multiplex gene editing tools derived from the Cas9 nuclease of Streptomyces pyogenes. They can target and modify a single nucleotide in the genome without inducing double-strand breaks (DSB) of the DNA helix.
François M. Seys +8 more
doaj +2 more sources
Conversion of Syngas from Entrained Flow Gasification of Biogenic Residues with Clostridium carboxidivorans and Clostridium autoethanogenum [PDF]
Synthesis gas fermentation is a microbial process, which uses anaerobic bacteria to convert CO-rich gases to organic acids and alcohols and thus presents a promising technology for the sustainable production of fuels and platform chemicals from renewable
Anton Rückel +5 more
doaj +2 more sources
Effects of dietary Clostridium autoethanogenum protein on the growth, disease resistance, intestinal digestion, immunity and microbiota structure of Litopenaeus vannamei reared at different water salinities [PDF]
The shortage of fishmeal (FM) resources limits the healthy development of aquaculture. Developing new protein sources to replace FM in aquatic feeds is an effective measure to alleviate this situation.
Jian Chen +12 more
doaj +2 more sources
Transcriptomic analysis reveals the immunomodulatory role of Clostridium autoethanogenum protein on Litopenaeus vannamei under variable salinity conditions [PDF]
Salinity is a critical environmental factor in aquaculture, and Clostridium autoethanogenum protein (CAP) shows potential as a new feed protein source.
Jian Chen +6 more
doaj +2 more sources
A new single-cell protein from Clostridium autoethanogenum as a functional protein for largemouth bass (Micropterus salmoides) [PDF]
Clostridium autoethanogenum protein (CAP) is a new single-cell protein source originating from inactivated bacteria. An in vitro digestion experiment and an 8-wk growth experiment were conducted to evaluate the molecular weight distribution of the CAP ...
Shifeng Ma +7 more
doaj +2 more sources
Clostridium autoethanogenum alters cofactor synthesis, redox metabolism, and lysine-acetylation in response to elevated H2:CO feedstock ratios for enhancing carbon capture efficiency [PDF]
Background Clostridium autoethanogenum is an acetogenic bacterium that autotrophically converts carbon monoxide (CO) and carbon dioxide (CO2) gases into bioproducts and fuels via the Wood–Ljungdahl pathway (WLP).
Megan E. Davin +10 more
doaj +2 more sources
Dietary fishmeal replacement by Clostridium autoethanogenum protein meal influences the nutritional and sensory quality of turbot (Scophthalmus maximus) via the TOR/AAR/AMPK pathways [PDF]
Clostridium autoethanogenum protein (CAP) is a promising protein source for aquaculture; however, how CAP influences fish quality is worth extensive research.
Zezheng Qi +4 more
doaj +2 more sources
Dietary Effect of Clostridium autoethanogenum Protein on Growth, Intestinal Histology and Flesh Lipid Metabolism of Largemouth Bass (Micropterus salmoides) Based on Metabolomics [PDF]
Clostridium autoethanogenum protein (CAP) is a new single-cell protein explored in aquatic feeds in recent years. This study investigated the dietary effects of CAP replacing fishmeal (FM) on the growth, intestinal histology and flesh metabolism of ...
Pinxian Yang +5 more
doaj +2 more sources
Evaluation of Clostridium autoethanogenum protein as a new protein source for broiler chickens in replacement of soybean meal [PDF]
Objective The object of this study was to investigate the effect of replacing soybean meal with Clostridium autoethanogenum protein (CAP) in broiler diets on growth performance, blood indicators, antioxidant capacity, and immune function. Methods A total
Xing Chen +8 more
doaj +2 more sources
Dietary supplementation with Clostridium autoethanogenum protein improves growth performance and promotes muscle protein synthesis by activating the mTOR signaling pathway of the broiler [PDF]
The experiment aimed to evaluate the effects of different ratios of Clostridium autoethanogenum protein (CAP) used in the diets on the growth performance, muscle quality, serum indexes, and mTOR pathway of white feather broilers.
Chunqiao Shan +7 more
doaj +2 more sources

