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Pathogenicity and virulence of Clostridium botulinum. [PDF]
Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor and the causative agent of botulism.
Rawson AM+3 more
europepmc +5 more sources
Preventing Foodborne Illness: Clostridium botulinum
Botulism is caused by the nerve toxins produced by the bacterium Clostridium botulinum, often resulting in a serious paralytic condition that can lead to death.
Keith R. Schneider+3 more
doaj +10 more sources
Septic shock due to Clostridium botulinum: a case report [PDF]
Background Clostridium botulinum is an anaerobic, Gram-positive, rod-shaped bacterium that forms spores and the neurotoxin botulinum. It is best known for its toxin-induced flaccid paralytic disease, which is deadly without correct treatment.
P. M. L. Zomer, M. J. A. Kamps
doaj +2 more sources
Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani. [PDF]
Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively ...
Popoff MR, Brüggemann H.
europepmc +2 more sources
Clostridium botulinum and Clostridium perfringens Occurrence in Kazakh Honey Samples
The aim of this study was to assess occurrence of Clostridium botulinum and Clostridium perfringens in honey samples from Kazakhstan. Analyses were carried out using a set of PCR methods for identification of anaerobic bacteria, and detection of toxin ...
Balgabay Maikanov+8 more
doaj +2 more sources
Clostridium botulinum Group I and Clostridium sporogenes are closely related bacteria responsible for foodborne, infant and wound botulism. A comparative genomic study with 556 highly diverse strains of C. botulinum Group I and C.
Jason Brunt+7 more
doaj +2 more sources
Functional characterisation of germinant receptors in Clostridium botulinum and Clostridium sporogenes presents novel insights into spore germination systems. [PDF]
Clostridium botulinum is a dangerous pathogen that forms the highly potent botulinum toxin, which when ingested causes a deadly neuroparalytic disease. The closely related Clostridium sporogenes is occasionally pathogenic, frequently associated with food
Jason Brunt+5 more
doaj +2 more sources
Sanger and shotgun sequencing of Clostridium botulinum strain Af84 type Af and its botulinum neurotoxin gene (bont) clusters identified the presence of three bont gene clusters rather than the expected two. The three toxin gene clusters consisted of bont
Nir Dover+6 more
doaj +2 more sources
Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant [PDF]
We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a
Barbara Schaub, MD+8 more
doaj +1 more source
Identification and enumeration of Clostridium spp. In sufu [PDF]
In this study, Clostridium spp. was counted in 49 Chinese commercial sufu samples, and 25 samples were detected Clostridium in all samples: the detection rate was 51.02%. About 93.87% of the samples contained Clostridium at low levels (log CFU/g<3.0) and
Qiong Xu+6 more
doaj +1 more source