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Pathogenicity and virulence of Clostridium botulinum. [PDF]

open access: yesVirulence, 2023
Clostridium botulinum, a polyphyletic Gram-positive taxon of bacteria, is classified purely by their ability to produce botulinum neurotoxin (BoNT). BoNT is the primary virulence factor and the causative agent of botulism.
Rawson AM   +3 more
europepmc   +5 more sources

Preventing Foodborne Illness: Clostridium botulinum

open access: bronzeEDIS, 2005
Botulism is caused by the nerve toxins produced by the bacterium Clostridium botulinum, often resulting in a serious paralytic condition that can lead to death.
Keith R. Schneider   +3 more
doaj   +10 more sources

Septic shock due to Clostridium botulinum: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2023
Background Clostridium botulinum is an anaerobic, Gram-positive, rod-shaped bacterium that forms spores and the neurotoxin botulinum. It is best known for its toxin-induced flaccid paralytic disease, which is deadly without correct treatment.
P. M. L. Zomer, M. J. A. Kamps
doaj   +2 more sources

Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani. [PDF]

open access: yesToxins (Basel), 2022
Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively ...
Popoff MR, Brüggemann H.
europepmc   +2 more sources

Clostridium botulinum and Clostridium perfringens Occurrence in Kazakh Honey Samples

open access: yesToxins, 2019
The aim of this study was to assess occurrence of Clostridium botulinum and Clostridium perfringens in honey samples from Kazakhstan. Analyses were carried out using a set of PCR methods for identification of anaerobic bacteria, and detection of toxin ...
Balgabay Maikanov   +8 more
doaj   +2 more sources

Diversity of the Genomes and Neurotoxins of Strains of Clostridium botulinum Group I and Clostridium sporogenes Associated with Foodborne, Infant and Wound Botulism

open access: yesToxins, 2020
Clostridium botulinum Group I and Clostridium sporogenes are closely related bacteria responsible for foodborne, infant and wound botulism. A comparative genomic study with 556 highly diverse strains of C. botulinum Group I and C.
Jason Brunt   +7 more
doaj   +2 more sources

Functional characterisation of germinant receptors in Clostridium botulinum and Clostridium sporogenes presents novel insights into spore germination systems. [PDF]

open access: yesPLoS Pathogens, 2014
Clostridium botulinum is a dangerous pathogen that forms the highly potent botulinum toxin, which when ingested causes a deadly neuroparalytic disease. The closely related Clostridium sporogenes is occasionally pathogenic, frequently associated with food
Jason Brunt   +5 more
doaj   +2 more sources

Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5.

open access: yesPLoS ONE, 2013
Sanger and shotgun sequencing of Clostridium botulinum strain Af84 type Af and its botulinum neurotoxin gene (bont) clusters identified the presence of three bont gene clusters rather than the expected two. The three toxin gene clusters consisted of bont
Nir Dover   +6 more
doaj   +2 more sources

Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant [PDF]

open access: yesJournal of Pediatrics: Clinical Practice
We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a
Barbara Schaub, MD   +8 more
doaj   +1 more source

Identification and enumeration of Clostridium spp. In sufu [PDF]

open access: yesE3S Web of Conferences, 2021
In this study, Clostridium spp. was counted in 49 Chinese commercial sufu samples, and 25 samples were detected Clostridium in all samples: the detection rate was 51.02%. About 93.87% of the samples contained Clostridium at low levels (log CFU/g<3.0) and
Qiong Xu   +6 more
doaj   +1 more source

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