Results 11 to 20 of about 36,820 (249)

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]

, 2013
Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
A Kronhardt, A Messmer, A Ménard, A Ménard, AA Verveen, AF Kintzer, AM Friedlander, Anika Bronnhuber, AW Artenstein, BA Krantz, C Andersen, C Bachmeyer, C Bachmeyer, C Petosa, Christoph Beitzinger, CT Bahner, D Blöcker, D Blöcker, DB Lacy, EM Nestorovich, EM Nestorovich, F Conti, F Orlik, F Orlik, F Tonello, F Tonello, F Wohnsland, G Hajós, G Timári, G Vitale, György Hajós, H Barth, H Barth, Holger Barth, I Zornetta, J Sun, J Wesche, JA Young, JC Milne, JL Elliott, K Cunningham, KA Bradley, Kerstin Duscha, L Abrami, L Abrami, L Abrami, L Abrami, L Song, Ludger Johannes, M Eigen, M Mock, Markus Huber-Lang, MJ Brown, NS Duesbery, PC Hanna, R Benz, R Benz, R Palkó, R Pellizzari, RJ Collier, RO Blaustein, RO Blaustein, Roland Benz, S Nekolla, SH Leppla, SM Bezrukov, SM Bezrukov, T Neumeyer, T Neumeyer, T Neumeyer, TC Dixon, V Escuyer, VA Karginov, VA Karginov, VA Karginov, Y Singh, Zsuzsanna Riedl   +76 more
core   +11 more sources

Adult Intestinal Toxemia Botulism

Toxins, 2020
Intoxication with botulinum neurotoxin can occur through various routes. Foodborne botulism results after consumption of food in which botulinum neurotoxin-producing clostridia (i.e., Clostridium botulinum or strains of Clostridium butyricum type E or ...
Richard A. Harris, Fabrizio Anniballi, John W. Austin   +2 more
doaj   +1 more source

Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro

Frontiers in Microbiology, 2022
Clostridium botulinum produces botulinum neurotoxin complexes that cause botulism. Previous studies elucidated the molecular pathogenesis of botulinum neurotoxin complexes; however, it currently remains unclear whether other components of the bacterium ...
Nobuhide Kobayashi, Kimihiro Abe, Sachiyo Akagi, Mayu Kitamura, Yoshitake Shiraishi, Aki Yamaguchi, Masahiro Yutani, Sho Amatsu, Takuhiro Matsumura, Nobuhiko Nomura, Nobuhiko Nomura, Noriyuki Ozaki, Nozomu Obana, Nozomu Obana, Yukako Fujinaga   +14 more
doaj   +1 more source

The binding of botulinum neurotoxins to different peripheral neurons [PDF]

, 2017
Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core   +1 more source

A pragmatic harm reduction approach to manage a large outbreak of wound botulism in people who inject drugs, Scotland 2015 [PDF]

, 2018
Background People who inject drugs (PWID) are at an increased risk of wound botulism, a potentially fatal acute paralytic illness. During the first 6 months of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland, which resulted ...
Amanda Weir, Andrew McAuley, CC McGuigan, CN Ramsay, Corinne Amar, D Akbulut, DJ Passaro, E MacDonald, E Tweed, European Centre for Disease Prevention and Control, Gauri Godbole, Gillian Penrice, GY Chang, Health Protection Scotland, Information Services Division (ISD), J McLauchlin, J Sobel, J Strang, JA Jones, JA Stoltz, K Alpers, K Dunleavy, Kathie Grant, Kirsten M. A. Trayner, Kirsty Roy, M Desai, M Harris, M Ragonnet-Cronin, M Schroeter, MG Booth, N Markwick, National Records of Scotland, NE Palmateer, Public Health England, Health Protection Scotland, Public Health Wales, and Public Health Agency Northern Ireland, RJ Gordon, SB Werner, Scottish Government, Scottish Health Protection Network, SJ Hahné, SR Offerman, TN Wenham, VD Hope, VD Hope, Y Soukup-Baljak   +43 more
core   +1 more source

Distribution of Clostridium botulinum [PDF]

Applied and Environmental Microbiology, 1980
The distribution of Clostridium botulinum in the natural environments of Denmark, The Faroe Islands, Iceland, Greenland, and Bangladesh was examined. A total of 684 samples were tested. Type E was found in 90% of samples from the aquatic environment of Denmark, including sediments from young artificial lakes, and in 86% of samples from the marine ...
openaire   +2 more sources

Wound Botulism Caused by Botulinum Neurotoxin Type A in a Chronic Parenteral Drug Abuser

Case Reports in Neurology, 2020
Botulism is an acute paralytic disease caused by botulinum neurotoxin (BoNT)-mediated inhibition of neurosignaling at the neuromuscular junction. BoNTs are produced by gram positive, anaerobic, spore-forming bacteria from the genus Clostridium,most ...
Sohun Awsare, David Chirikian, Forshing Lui   +2 more
doaj   +1 more source

A survey of traditional Iranian food products for contamination with toxigenic Clostridium botulinum

Journal of Infection and Public Health, 2009
Summary: This study aimed to determine the rate of Clostridium botulinum contamination in some traditional Iranian food products (cheese, kashk and salted fish) and evaluate the efficacy of the mouse bioassay method in detection of C. botulinum toxins in
H.R. Tavakoli, M. Aghazadeh Meshgi, N. Jonaidi Jafari, M. Izadi, R. Ranjbar, A.A. Imani Fooladi   +5 more
doaj   +1 more source

Exploration of the Diversity of Clustered Regularly Interspaced Short Palindromic Repeats-Cas Systems in Clostridium novyi sensu lato

Frontiers in Microbiology, 2021
Classified as the genospecies Clostridium novyi sensu lato and distributed into four lineages (I–IV), Clostridium botulinum (group III), Clostridium novyi, and Clostridium haemolyticum are clostridial pathogens that cause animal diseases.
Thibault Le Gratiet, Thibault Le Gratiet, Caroline Le Marechal, Marie Devaere, Marianne Chemaly, Cédric Woudstra   +5 more
doaj   +1 more source

The food safety impact of salt and sodium reduction initiatives [PDF]

, 2014
Excessive or high salt or sodium intake is known to cause hypertension and other diseases. Within the United Kingdom voluntary targets for salt reduction have been set and laid out in the Secretary of State responsibility deal.
ACMSF, Davidson PM, Enderle J, Scientific Advisory Committee on Nutrition (SCAN), Wallis K, Wilson R, Zarei M   +6 more
core   +1 more source