Results 11 to 20 of about 110,558 (326)
Clinics in Laboratory Medicine, 2010 Clostridium difficile infections (CDIs) have emerged as one of the principal threats to the health of hospitalized and immunocompromised patients. The importance of C difficile colonization is increasingly recognized not only as a source for false-positive clinical testing but also as a source of new infections within hospitals and other health care ...
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Cancer, Volume 129, Issue 2, Page 283-295, 15 January 2023., 2023 Abstract Background Antibody–drug conjugates (ADCs) have complex molecular structures and have been tested in numerous clinical trials. Therefore, understanding the mechanisms of their toxicity when applied in medical practice is of high importance. Methods In a systematic review and meta‐analysis of data gathered from different scientific databases ...
Youwen Zhu +3 more
wiley +1 more source
Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors
European Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023 Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
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Isolation and purification of Tartary buckwheat polysaccharides and their effect on gut microbiota
Food Science &Nutrition, Volume 11, Issue 1, Page 408-417, January 2023., 2023 The Tartary buckwheat polysaccharides present in different fractions had specific probiotic effects. The composition of gut microbiota was significantly altered by adding Tartary buckwheat polysaccharides during fecal fermentation. Tartary buckwheat can provide specific dietary polysaccharide sources to modulate and maintain gut microbiota diversity ...
Yue Xiang +7 more
wiley +1 more source
Microbiology Independent Research Journal, 2020 Пациенты детского онкологического стационара находятся в группе риска развития Clostridium difficile инфекции. Цель данного исследования состояла в определении степени риска развития Clostridium difficile инфекции в детском онкологическом стационаре ...
М. Г. Швыдкая +3 more
doaj +1 more source
Charting the landscape of the environmental exposome
iMeta, Volume 1, Issue 4, December 2022., 2022 We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei +6 more
wiley +1 more source
Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis
iMeta, Volume 1, Issue 4, December 2022., 2022 Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma +3 more
wiley +1 more source
Clostridium difficile infection [PDF]
Nature Reviews Disease Primers, 2016 Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C. difficile is the leading cause of health-care-associated infective diarrhoea. The life cycle of C.
Smits, W.K. +4 more
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Metabolite profiling of human‐originated Lachnospiraceae at the strain level
iMeta, Volume 1, Issue 4, December 2022., 2022 The human‐originated Lachnospiraceae biobank included 77 species was constructed. In vitro metabolite profiling of 110 Lachnospiraceae strains yielded 242 metabolites of 17 categories. Many Lachnospiraceae strains produce short‐chain fatty acids, and Agathobacter rectalis strain Lach‐101 and Coprococcus comes strain NSJ‐173 are the top two butyric acid
Rashidin Abdugheni +11 more
wiley +1 more source
iMeta, Volume 1, Issue 4, December 2022., 2022 In this study, we applied an algorithm to the keystone species identification in the gut microbiome, based on current causal inference theories and the dynamic intervention simulation. We identified the nonalcoholic steatohepatitis (NASH) keystone species combination, represented by Porphyromonas loveana, Alistipes indistinctus, and Dialister ...
Dingfeng Wu +9 more
wiley +1 more source