Plant-Derived Xanthones against Clostridial Enteric Infections
Antibiotics, 2023 Intestinal bacterial infections are a major threat to human and animal health. In this study, we found plant-derived antibacterial xanthones, particularly α-mangostin (AMG) from the mangosteen peel, exhibiting extraordinary activities against Clostridium
Ying Liu +4 more
doaj +1 more source
Clostridium difficile Infection in Children [PDF]
JAMA Pediatrics, 2013 Clostridium difficile is the most common cause of health care-associated diarrhea among adults in the United States and is associated with significant morbidity and mortality. During the past decade, the epidemiology of C difficile infection (CDI) has changed, including a rise in the rate and severity of infection related to the emergence of a ...
Julia S. Sammons +2 more
openaire +2 more sources
Probiotic‐Based Materials as Living Therapeutics
Advanced Materials, EarlyView.Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
wiley +1 more source
Clostridium septicum sepsis and colorectal cancer - a reminder
World Journal of Surgical Oncology, 2009 Background Spontaneous clostridium septicum infections are rare and are associated with a high mortality. Association of clostridium infection with colorectal malignancies have been previously reported and most cases are described in tumours of the ...
McCloud Jonathon M +2 more
doaj +1 more source
Lean back and wait for the alarm? Testing an automated alarm system for nosocomial outbreaks to provide support for infection control professionals [PDF]
, 2020 INTRODUCTION: Outbreaks of communicable diseases in hospitals need to be quickly detected in order to enable immediate control. The increasing digitalization of hospital data processing offers potential solutions for automated outbreak detection systems
Aghdassi, Seven Johannes Sam +9 more
core +1 more source
The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset
Advanced Science, EarlyView.The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng +22 more
wiley +1 more source
Reducing the Risk of Severe Complications among Patients with Clostridium difficile Infection
Canadian Journal of Gastroenterology, 2011 BACKGROUND: The incidence and severity of Clostridium difficile infections are increasing, and there is a need to optimize the prevention of complicated disease.
Kamran Manek +3 more
doaj +1 more source
Surveillance of Clostridium difficile infection during the period 2008-2009 in Rho hospital
Microbiologia Medica, 2011 Clostridium difficile is a Gram positive bacillus, anaerobic, sporogenous, with oro-faecal transmission. The formation of the spores can persist in a long time, encouraging the transmission.
Cristina Rescaldani +4 more
doaj +1 more source
UK Renal Registry 18th Annual Report : Chapter 12 Epidemiology of Reported Infections amongst Patients Receiving Dialysis for Established Renal Failure in England 2013 to 2014: a Joint Report from Public Health England and the UK Renal Registry [PDF]
, 2016 From 1st May 2013 to 30th April 2014 there were 35 episodes of Methicillin resistant Staphylococcus aureus (MRSA) bacteraemia in established renal failure patients on dialysis.
Caskey, Fergus +6 more
core +4 more sources
Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica
Advanced Science, EarlyView.The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon +8 more
wiley +1 more source