Results 11 to 20 of about 18,028 (184)

Reevaluation of whether a Functional Agr-like Quorum-Sensing System Is Necessary for Production of Wild-Type Levels of Epsilon-Toxin by Clostridium perfringens Type D Strains [PDF]

mBio, 2022
Clostridium perfringens type B and D strains produce epsilon-toxin (ETX). Our 2011 mBio study (mBio 2:e00275-11, 2011, https://doi.org/10.1128/mBio.00275-11) reported that the Agr quorum-sensing (QS) system regulates ETX production by type D strain ...
Iman Mehdizadeh Gohari, Jihong Li, Julian I. Rood, Bruce A. McClane   +3 more
doaj   +2 more sources

Outbreak of Clostridium perfringens type D enterotoxemia in sheep

Semina: Ciências Agrárias, 2019
This work describes the first Brazilian laboratory-confirmed outbreak of enterotoxemia caused by Clostridium perfringens type D in sheep, which occurred in the state of Paraná.
Felipe Masiero Salvarani, Mayane Faccin, Nayra Fernanda de Queiroz Ramos Freitas, Mônica Regina de Matos, Edismair Carvalho Garcia, Geane Maciel Pagliosa, José Diomedes Barbosa, Francisco Carlos Faria Lobato, Aline de Marco Viott   +8 more
doaj   +3 more sources

Design of a chitosan-based nano vaccine against epsilon toxin of Clostridium perfringens type D and evaluation of its immunogenicity in BALB/c mice [PDF]

Research in Pharmaceutical Sciences, 2021
Background and purpose: Clostridium perfringens is an anaerobic, spore-forming, and pathogenic bacterium that causes intestinal diseases in humans and animals.
Farnaz Poorhassan, Fahimeh Nemati, Parvaneh Saffarian, Seyed Ali Mirhosseini, Mohammad Javad Motamedi   +4 more
doaj   +2 more sources

In silico vaccine design: Targeting highly epitopic regions of Clostridium perfringens type D epsilon toxin and Clostridium novyi type B alpha toxin for optimal immunogenicity [PDF]

Computational and Structural Biotechnology Journal
Livestock infections caused by highly toxic bacteria, such as Clostridium perfringens type D and Clostridium novyi type B, present significant challenges in veterinary medicine.
Nastaran Ashoori, Mohammad Mehdi Ranjbar, Romana Schirhagl   +2 more
doaj   +2 more sources

Effect of Clostridium perfringens type D toxin on Caenorhabditis elegans

NAM Journal
The search for an alternative in vivo diagnostic method for Clostridium perfringens toxinotype D (CPD) aimed to evaluate the susceptibility of the nematode Caenorhabditis elegans CF512 CPD as a substitute for conventional biological models.
Ana María Delia Pereyra, Ximena Blanco Crivelli, Mariana Sanin, Adriana Bentancor, Cecilia Cundon   +4 more
doaj   +2 more sources

Production of Multiple Variants of the Antimicrobial Sactipeptide Gnavucin D by the Human Gut Isolate Mediterraneibacter gnavus HB038. [PDF]

Microbiologyopen
Gnavucin D, a novel antibacterial sactipeptide produced by Mediterraneibacter gnavus HB038, exhibits activity against multiple pathogens, including Clostridium perfringens, Streptococcus agalactiae, Bacillus cereus, and vancomycin‐resistant Enterococcus.
Ding M, de Farias FM, O'Connor PM, Huang X, Ross FC, Kennedy EC, Hawkes CP, Hill C, Stanton C, Ross RP.   +9 more
europepmc   +2 more sources

Seasonal Prevalence, Molecular Identification and Therapeutic Management of Enterotoxemia Caused by Clostridium perfringens Type D in Goats of Peshawar and Charsadda Districts, Pakistan

Veterinary Medicine and Science
Clostridium perfringens is classified into different types, of which Type D, due to its production of epsilon toxin, can cause enterotoxemia, a fatal disease in ruminants, particularly goats.
Inam Ul Haq, Haq Aman Ullah, Muqadar Shah, Rifat Ullah Khan, Shabana Naz, Antonella Perillo, Sohail Ahmad, Ibrahim A. Alhidary   +7 more
doaj   +2 more sources

Biofilm Formation and Spore-Mediated Persistence of Clostridium perfringens in Meat and Poultry Processing Environments and Their Implications for Control Strategies. [PDF]

J Food Sci
ABSTRACT Clostridium perfringens (C. perfringens) biofilms pose a persistent challenge in meat and poultry processing environments due to their structural resilience, spore‐mediated survival and toxin‐associated virulence. These biofilms readily develop on food‐contact surfaces under typical processing conditions including organic residue accumulation,
Chowdhury MAH, Reem CSA, Ashrafudoulla M, Yoon HJ, Ha SD.   +4 more
europepmc   +2 more sources

Pathology and Pathogenesis of Brain Lesions Produced by Clostridium perfringens Type D Epsilon Toxin. [PDF]

Int J Mol Sci, 2022
Clostridium perfringens type D epsilon toxin (ETX) produces severe, and frequently fatal, neurologic disease in ruminant livestock. The disorder is of worldwide distribution and, although vaccination has reduced its prevalence, ETX still causes substantial economic loss in livestock enterprises.
Finnie JW, Uzal FA.
europepmc   +5 more sources

Prevalence of Clostridium perfringens infection and virulence genes molecular study in broiler chickens [PDF]

Benha Veterinary Medical Journal, 2020
Clostridium perfringens (C. perfringens) produces toxins that cause necrotic enteritis (NE) in broiler chickens resulting in sever losses in poultry industry. This study aimed to investigate the prevalence of C.
Shreen Mayouf, Mohammed El- Bardisy, Ashraf Abd El-Tawab, Amira Rizk   +3 more
doaj   +1 more source