Determination of Type and Molecular Identity of Clostridium perfringens Isolated from Patients with Multiple Sclerosis (MS) [PDF]
Background & Objectives: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system (CNS). Clostridium perfringens ε-toxin (ETX) can cause emerging complications of MS due to its tendency to the blood-brain barrier.
Maryam Sheykhzade Asadi +2 more
doaj
Objectives: Clostridium perfringens (C. perfringens) can cause intestinal diseases in livestock and humans, which seriously threatens the healthy development of animal husbandry and human food safety. Here, the characteristics of antimicrobial resistance
Wang Xiaoting +13 more
doaj +1 more source
Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis [PDF]
Background: Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens type A. Due to the rapid progress and fatal outcome of the disease, vaccination would be of high value. In this study, C.
Deprez, Piet +10 more
core +2 more sources
Clostridium perfringens is a bacterial species of importance to both public and animal health. The gene optrA is the first gene that confers resistance to the tedizolid, a last-resort antimicrobial agent in human medicine.
Ke Wu +15 more
doaj +1 more source
Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet +6 more
core +3 more sources
Epsilon-Toxin Plasmids of Clostridium perfringens Type D Are Conjugative [PDF]
ABSTRACT Isolates of Clostridium perfringens type D produce the potent epsilon-toxin (a CDC/U.S. Department of Agriculture overlap class B select agent) and are responsible for several economically significant enterotoxemias of domestic livestock.
Meredith L, Hughes +7 more
openaire +2 more sources
Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]
Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Dobrow, Sebastian +7 more
core +1 more source
Genotyping of Clostridium perfringens associated with sudden death in cattle
Toxigenic types of Clostridium perfringens are significant causative agents of enteric disease in domestic animals, although type E is presumably rare, appearing as an uncommon cause of enterotoxemia of lambs, calves and rabbits.
S Miyashiro, L Baldassi, AFC Nassar
doaj +1 more source
Variable protection against experimental broiler necrotic enteritis after immunisation with the C-terminal fragment of Clostridium perfringens alpha-toxin and a non-toxic NetB variant [PDF]
Necrotic enteritis toxin B (NetB) is a pore-forming toxin produced by Clostridium perfringens and has been shown to play a key role in avian necrotic enteritis (NE), a disease causing significant costs to the poultry production industry worldwide.
Bokori-Brown, Monika +5 more
core +3 more sources
Enterotoxemia is a severe and peracute disease caused by Clostridium perfringens (C. perfringens) rendering high mortality leading to huge economic losses, especially in small ruminants.
Riaz Hussain +8 more
doaj +1 more source

