Proteolytic processing and activation of Clostridium perfringens epsilon toxin by caprine small intestinal contents. [PDF]
, 2014 Epsilon toxin (ETX), a pore-forming toxin produced by type B and D strains of Clostridium perfringens, mediates severe enterotoxemia in livestock and possibly plays a role in human disease.
Freedman, John C +3 more
core +2 more sources
Clostridium perfringens types A and D associated with enterotoxemia in an 18-month-old goat
Journal of Venomous Animals and Toxins including Tropical Diseases, 2007 Postmortem examination of a Boer buck that died peracutely revealed bowel and liver diffusely congested and edematous. Kidney was apparently edematous. Clostridium perfringens type A was isolated from bowel and type D from kidney. Microscopic examination
S. Miyashiro +4 more
doaj +1 more source
The Gut Microbiome in Neuromyelitis Optica. [PDF]
, 2017 Neuromyelitis optica (NMO) is a rare, disabling, sometimes fatal central nervous system inflammatory demyelinating disease that is associated with antibodies ("NMO IgG") that target the water channel protein aquaporin-4 (AQP4) expressed on astrocytes ...
Baranzini, Sergio E +3 more
core +1 more source
The Pathology of Peracute Experimental Clostridium Perfringens Type D Enterotoxemia in Sheep [PDF]
Journal of Veterinary Diagnostic Investigation, 2004 The pathological findings in sheep with peracute experimental Clostridium perfringens type D enterotoxemia are described. Of 16 animals inoculated intraduodenally with a whole culture of this microorganism and a starch solution in the abomasum, 12 developed clinical signs including increased respiratory efforts, recumbency, paddling, bleating ...
Uzal F.A. +4 more
openaire +3 more sources
Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression. [PDF]
PLoS ONE, 2009 Clostridium perfringens type A food poisoning (FP) is usually caused by C. perfringens type A strains that carry a chromosomal enterotoxin gene (cpe) and produce spores with exceptional resistance against heat and nitrites.
Jihong Li +3 more
doaj +1 more source
Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins. [PDF]
, 2018 Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic, neurologic and intestinal infections in humans and animals. The major toxins involved in diseases are alpha (CPA), beta (CPB), epsilon (ETX), iota (ITX), enterotoxin (
McClane, Bruce A +2 more
core +3 more sources
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophageâmediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
In Vitro Antimicrobial Activities of Organic Acids and Their Derivatives on Several Species of Gram-Negative and Gram-Positive Bacteria. [PDF]
, 2019 The objective of this study was to determine the in vitro antimicrobial activity of several organic acids and their derivatives against Gram-positive (G+) and Gram-negative (G-) bacteria.
Atwill, Edward Robert +8 more
core +1 more source
A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats
Advanced Science, EarlyView.ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang +13 more
wiley +1 more source
Pathogens, 2021 The present study aimed to determine the occurrence, genotypes, and antimicrobial resistance of Clostridium perfringens (C. perfringens) and Clostridioides difficile (C.
Mahmoud Fayez +7 more
doaj +1 more source