Results 81 to 90 of about 34,207 (226)

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids [PDF]

, 2013
DA - 20130125 IS - 1471-2180 (Electronic) IS - 1471-2180 (Linking) LA - eng PT - Journal Article PT - Research Support, Non-U.S.
McKain, Nest, Richardson, Anthony J, Wallace, R John   +2 more
core   +2 more sources

Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]

, 2020
Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz, Hauser, Anja E., Kröger, Susan, Martínez-Vallespín, Beatriz, Niesner, Raluca, Pieper, Robert, Vahjen, Wilfried, Zentek, Jürgen   +7 more
core   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Clostridium perfringens isolate typing by multiplex PCR

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Clostridium perfringens is an important pathogen that provokes numerous different diseases. This bacterium is classified into five different types, each of which capable of causing a different disease.
MR Ahsani, MR Mohammadabadi, MB Shamsaddini   +2 more
doaj   +1 more source

Bacteriocins: Novel Solutions to Age Old Spore-Related Problems? [PDF]

, 2016
peer-reviewedBacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria, which have the ability to kill or inhibit other bacteria. Many bacteriocins are produced by food grade lactic acid bacteria (LAB).
Cotter, Paul D., Egan, Kevin, Field, Des, Hill, Colin, Rea, Mary, Ross, R Paul   +5 more
core   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

Diabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli, Chloé Magnan, Florian Salipante, Adeline Dubois, Sophie Schuldiner, Nicolas Cellier, Albert Sotto, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy   +8 more
wiley   +1 more source

Use of an EZ-Tn5-based random mutagenesis system to identify a novel toxin regulatory locus in Clostridium perfringens strain 13. [PDF]

PLoS ONE, 2009
BACKGROUND:Although useful for probing bacterial pathogenesis and physiology, current random mutagenesis systems suffer limitations for studying the toxin-producing bacterium Clostridium perfringens.
Jorge E Vidal, Jianming Chen, Jihong Li, Bruce A McClane   +3 more
doaj   +1 more source

Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells [PDF]

, 2019
Claudins regulate paracellular permeability in different tissues. The claudin-binding domain of Clostridium perfringens enterotoxin (cCPE) is a known modulator of a claudin subset. However, it does not efficiently bind to claudin-1 (Cldn1).
Beier, Laura-Sophie, Bergmann, Sophia, Brandner, Johanna M., Eichner, Miriam, Kramer, Holger B., Krause, Gerd, Piontek, Anna, Piontek, Jörg, Protze, Jonas, Rossa, Jan, Vidal-y-Sy, Sabine, Woodhouse, Stephen, Zitzmann, Nicole   +12 more
core   +2 more sources

Sharing Is Caring?—Pathogens and Pathogen‐Specific Antibodies in Arctic Endemic Seal Species and the Newly Sympatric Harbor Seals in Kongsfjorden, Svalbard

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Climate change associated transformations of Arctic marine ecosystems are having detrimental impacts on Arctic endemic marine mammals. However, warming conditions are providing new habitats for temperate marine mammals, some of which are expanding into Arctic regions, posing a threat of novel pathogen introduction and disease transmission.
Luca A. Schick, Kit M. Kovacs, Christian Lydersen, Simon Rohner, Ellen Prenger‐Berninghoff, Carsten Heydel, Christa Ewers, Alexander Postel, Nele Gremmel, Paul Becher, Christina Strube, Ursula Siebert   +11 more
wiley   +1 more source