Results 81 to 90 of about 7,658 (254)

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Microencapsulation of clove essential oil with gelatin and alginate

, 2019
Content: Essential oils are of commercial interest primarily because of their potential antimicrobial, antifungal and antioxidant properties and for being of natural origin, which generally represents lower risk to the environment and human health. Clove essential oil not only contains many kinds of biological active compositions but also has highly ...
Kopp, Victoria V., Agustini, C. B., dos Santos, J. H. Z., Gutterres, M.   +3 more
openaire   +1 more source

Isolation of Clove Bud and Star Anise Essential Oil by Supercritical CO2Extraction

LWT - Food Science and Technology, 1998
Abstract Clove bud and star anise volatile oils were isolated by supercritical CO 2 extraction coupled to a fractional separation technique. Gas chromatography–mass spectrometry analysis of the various fractions obtained in different extraction and fractionation conditions allowed the identification of the best operating conditions for the isolation ...
REVERCHON, Ernesto, DELLA PORTA, Giovanna, D'URSO E, TADDEO R.   +3 more
openaire   +2 more sources

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Antioxidant Application of Clove (Syzygium aromaticum) Essential Oil in Meat and Meat Products: A Systematic Review

Plants
The essential oil isolated from clove (Syzygium aromaticum) is used in food, medicine, cosmetics, agriculture, and aromatherapy for its antimicrobial, antioxidant, and analgesic properties.
Eduardo Valarezo, Guicela Ledesma-Monteros, Ximena Jaramillo-Fierro, Matteo Radice, Miguel Angel Meneses   +4 more
doaj   +1 more source

Therapeutic efficacy and dermal safety of topical clove essential oil spray against bacterial, yeast, and fungal skin infections in rat models: A pilot non-inferiority study [PDF]

Veterinary World
Background and Aim: Infectious dermatitis caused by bacterial, yeast, and fungal pathogens is an important veterinary concern, while antimicrobial resistance and adverse effects associated with conventional therapies highlight the need for safe topical ...
Eakachai Thongkham, Glenn Neville Borlace, Ranee Singh, Ketmanee Senaphan, Jareerat Aiemsaard   +4 more
doaj   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

Chemical composition and content of essential oil from the bud of cultivated Turkish clove

BioResources, 2007
In this study, clove bud oil, which was cultivated in the Mediterranean region of Turkey, was provided from a private essential oil company in Turkey. Essential oil from clove (Syzygium aromaticum L.) was obtained from steam-distillation method, and its ...
Kollmannsberger, H., Nitz, S., Ertaş, M., Alma, M. H.   +3 more
doaj  

Optimization of a method for preparing solid complexes of essential clove oil with β‐cyclodextrins

Journal of the Science of Food and Agriculture, 2016
AbstractBACKGROUNDClove oil (CO) is an aromatic oily liquid used in the food, cosmetics and pharmaceutical industries for its functional properties. However, its disadvantages of pungent taste, volatility, light sensitivity and poor water solubility can be solved by applying microencapsulation or complexation techniques.RESULTSEssential CO was ...
Hernández Sánchez, Pilar, Guardiola, Lucía, Gabaldón, José Antonio, López Miranda, Santiago, Serrano Martínez, Ana, Núñez Delicado, Estrella   +5 more
openaire   +3 more sources