Results 91 to 100 of about 63,990 (294)
The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status [PDF]
Mental Health ClinicianClozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug events. Estrogen-
Alyssa K. Kuhn +4 more
doaj +1 more source
Case Reports in Psychiatry, 2021 Clozapine, the choice atypical antipsychotic for refractory schizophrenia, schizoaffective disorder, and bipolar disorder, has been shown to reduce positive and negative symptoms of schizophrenia.
Melissa Sussman +4 more
doaj +1 more source
Use of cardiovascular and antidiabetic drugs before and after starting with clozapine versus other antipsychotic drugs:a Dutch database study [PDF]
, 2020 Reports of decreased mortality among patients with schizophrenia who use clozapine may be biased if clozapine is prescribed to relatively healthy patients and if intensive monitoring during its use prevents (under-treatment of) somatic disorder. We aimed
Selten, Jean-Paul +3 more
core +2 more sources
Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Journal of Hospital Medicine, EarlyView.Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta +8 more
wiley +1 more source
In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications
Macromolecular Materials and Engineering, EarlyView.Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian +2 more
wiley +1 more source
Clozapine-Induced Pericarditis [PDF]
, 2011 Objective: To report a case of a patient treated with clozapine who developed pericarditis with pericardial effusion that resolved when the drug was discontinued.
Ivanovic-Kovacevic, S +5 more
core +2 more sources
Dynamic Video Assessment of Axial Postural Abnormalities in Parkinson's Disease: A Pilot Study
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background Axial postural abnormalities (APAs) are frequent and disabling axial symptoms of Parkinson's disease (PD). Image‐based measurement is considered the gold standard but may not accurately detect the true severity of APAs because these symptoms can appear or get worse under dynamic conditions.
Carlo Alberto Artusi +7 more
wiley +1 more source
Indian Journal of Psychological Medicine, 2011 Few studies reported the efficacy and safety in combination of clozapine and electroconvulsive therapy (ECT) in schizophrenia; systematic studies are lacking. Side effects like seizure, and confusional state are reported.
N Manjunatha +4 more
doaj +1 more source
Antipsychotic Drug Use: Managing Cardiometabolic and Cost Effects [PDF]
, 2018 Across the US, 30%, or approximately one third of people meet the criteria for at least one mental illness.1 Of those with severe mental illness (SMI), namely schizophrenia and bipolar disorder, the mortality rate is more than twofold compared to the ...
Braga, Olivia G
core +1 more source
Can Valproic Acid be an Inducer of Clozapine Metabolism? [PDF]
, 2014 Introduction: Prior clozapine studies indicated no effects, mild inhibition or induction of valproic acid (VPA) on clozapine metabolism. The hypotheses that (i) VPA is a net inducer of clozapine metabolism, and (ii) smoking modifies this inductive effect
Ansermot, N. +5 more
core +1 more source