Results 101 to 110 of about 76,424 (294)
Metabool syndroom bij de behandeling met clozapine [PDF]
, 2009 Metabolic syndrome during clozapine treatment Objective: To assess the prevalence of metabolic syndrome in inpatients with psychotic disorders treated with clozapine for at least one year.
Heijden, F.M.M.A. (Frank) van der +5 more
core +1 more source
Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes [PDF]
, 2018 The realisation of the therapeutic potential of targeting the M1 muscarinic acetylcholine receptor (M1 mAChR) for the treatment of cognitive decline in Alzheimer's disease has prompted the discovery of M1 mAChR ligands showing efficacy in alleviating ...
Bradley, Sophie J. +14 more
core +1 more source
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, EarlyView.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Clozapine-induced myocarditis: a case report and literature review [PDF]
, 2022 I. Angélico Ferreira +4 more
openalex +1 more source
GPi‐DBS for SERAC1‐Related Dystonia‐Parkinsonism
Movement Disorders Clinical Practice, EarlyView.
Vidal Yahya +13 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Point‐of‐care testing (POCT) for hematology enables clinicians to access actionable results during patient visits, supporting timely decisions such as transfusions or chemotherapy adjustments. However, POCT analyzers must demonstrate clinical performance comparable to centralized laboratory systems. We conducted a proof‐of‐concept
Ryan C. Shean, Sterling T. Bennett
wiley +1 more source
Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley +1 more source
Combination of clozapine with an atypical antipsychotic: a meta-analysis [PDF]
, 2017 Purpose The purpose of this paper is to review the efficacy of atypical antipsychotics in combination with clozapine. Previous meta-analyses have assessed the use of both typical and atypical antipsychotics in combination with clozapine, combination ...
McGarry, Kenneth, Rolph, Lauren
core +1 more source
Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 588-591, April 2025.The spectrum of psychosis is highly relevant to child and adolescent mental health. Psychotic symptoms are common in children and adolescents. The onset of psychotic disorders is often preceded by neurodevelopmental problems in early childhood, and some 13% of adolescents attending specialist mental health services will later be diagnosed with a ...
James G. Scott
wiley +1 more source
Sudden Cardiac Death with Clozapine and Lorazepam Combination [PDF]
, 2012 Objective: To report a case of sudden cardiac death in a patient taking a combination of clozapine and lorazepam. Case summary: A 31-year-old white man with schizophrenia was found dead at his apartment.
Bhatia, Subhash C. +4 more
core +1 more source