Results 111 to 120 of about 42,559 (244)

An Epileptic Girl With Erotomania Using Carbamazepine|Resistant to Treatment and Challenge of Starting Clozapine

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The management of treatment‐resistant erotomania in patients with epilepsy requires a cautious pharmacological approach. This case demonstrates that replacing carbamazepine with valproic acid enabled the safe initiation of clozapine, resulting in resolution of erotomanic delusions while maintaining effective seizure control.
Fateme Roham   +4 more
wiley   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

COVID‐19 Infection Changed P300 Latency in Patients With Psychosis: A Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims The COVID‐19 pandemic raises concerns about neurological impacts on individuals with mental health conditions, particularly cognitive function. P300 event‐related potential (ERP) latency is a validated neurophysiological marker of attention and working memory.
Xiaofeng Jiang   +4 more
wiley   +1 more source

A Rational Approach to Pharmacotherapy in Pregnancy

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen   +2 more
wiley   +1 more source

Reduction in costs of inpatient stay associated with clozapine treatment: A retrospective study [PDF]

open access: bronze, 1998
Catherine Lyons   +5 more
openalex   +1 more source

Development and Validation of a Multigene Panel for Pharmacogenomics Testing Using Next‐Generation Sequencing for Routine Clinical Practice

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Pharmacogenomics (PGx) is a rapidly evolving field that aims to personalize medicine by identifying genetic variations that influence drug response. While next‐generation sequencing (NGS)–based applications are not yet widely adopted in clinical routine, this study aimed to validate 9 genes of the NGS‐based Ion AmpliSeq Pharmacogenomics Panel ...
Yaowaluck Hongkaew   +7 more
wiley   +1 more source

Clozapine-induced massive hematemesis: A rare case report

open access: diamond, 2019
Javed Ather Siddiqui   +2 more
openalex   +1 more source

An open‐label study on ulotaront's effects on insulin‐glucose regulation in schizophrenia patients with metabolic syndrome and prediabetes: Part I

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 103-111, January 2026.
Abstract Aims Ulotaront is an investigational trace amine‐associated receptor 1 (TAAR1) agonist demonstrated to slow gastric emptying in schizophrenia patients with metabolic syndrome (MetSyn) and prediabetes type 2. Here we evaluate the effects of ulotaront on glucose‐insulin dynamics in schizophrenia patients with MetSyn and prediabetes.
Snezana Milanovic   +10 more
wiley   +1 more source

Heartfelt intervention: A role for PVN oxytocin neurons in the prediabetic heart

open access: yes
The Journal of Physiology, EarlyView.
Grace K. Nielsen   +2 more
wiley   +1 more source

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