Results 141 to 150 of about 61,552 (282)
Acta Psychiatrica Scandinavica, Volume 151, Issue 6, Page 719-730, June 2025.ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Bee Leng Per +5 more
wiley +1 more source
Clozapine in the community [PDF]
British Journal of Psychiatry, 1992 Michael Phelan +2 more
openaire +3 more sources
Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1338-1357, May 2025.Tuberculosis (TB) is a major health burden in Africa. Although TB is treatable, anti‐TB drugs are associated with adverse drug reactions (ADRs), which are partly attributed to pharmacogenetic variation. The distribution of star alleles (haplotypes) influencing anti‐TB drug metabolism is unknown in many African populations.
Thandeka V.B. Malinga +6 more
wiley +1 more source
Astrocytes Mediate Psychostimulant‐Induced Alterations of Spike‐Timing Dependent Synaptic Plasticity
Glia, Volume 73, Issue 5, Page 1051-1067, May 2025.Main Points Cocaine and amphetamine stimulates astrocytes and downregulates the GLT‐1. The dysfunction in GLT‐1 modify EPSP kinetics and modulate STDP, switching LTP to LTD in psychostimulant‐treated mice. These effects were restored by upregulation of GLT‐1.
Samuel Alberquilla +7 more
wiley +1 more source
BJPsych OpenAims According to The Medicines and Healthcare products Regulatory Agency (MHRA) Drug safety update in August 2020 regarding clozapine, monitoring blood clozapine levels for toxicity is now advised in certain clinical situations such as when a patient ...
Kamran Mahmood +3 more
doaj +1 more source
Factors That Influence Prescribing in Borderline Personality Disorder: A Systematic Review
Personality and Mental Health, Volume 19, Issue 2, May 2025.ABSTRACT Borderline personality disorder (BPD) is a psychiatric condition characterised by pervasive patterns of thinking and feeling, which can lead to social dysfunction and poor mental health. BPD has a significant impact not just on individuals with the diagnosis but also on those around them. Currently, no medication is licenced for BPD.
Joshua Confue +3 more
wiley +1 more source
Clozapine-induced potentiation of latent inhibition is due to its action in the conditioning stage: implications for the mechanism of action of antipsychotic drugs [PDF]
, 1999 Eran Shadach, Joram Feldon, Ina Weiner
openalex +1 more source
Medical Journal of Australia, Volume 222, Issue 7, Page 339-347, April 2025.Abstract Objective To compare the toxicity (relative to population use) and lethality (relative to poisoning events) of medicines involved in poisoning suicides in Australia; to determine the proportions of cases in which the medicines had recently been dispensed to the deceased person.
Jessy Lim +6 more
wiley +1 more source
Psychiatric Research and Clinical PracticeBackground and Hypothesis Clozapine is an effective yet underutilized treatment for treatment‐resistant schizophrenia spectrum disorders. This study aimed to identify factors affecting clozapine prescribing patterns among patients with treatment ...
Kathleen Shangraw +8 more
doaj +1 more source
Commentary: the risks of enforcing clozapine therapy [PDF]
, 1999 Thomas R. E. Barnes
openalex +1 more source