Results 71 to 80 of about 134,552 (311)
Estimation of Genetic Parameters for Egg Production and Clutch Traits in Lindian Chickens
To accelerate breeding progress for egg production traits in Lindian chickens, the genetic parameters for egg production and clutch-related traits in Lindian chickens were evaluated in the present study.
Jiacheng Liu +9 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Directional gear ratio transmissions [PDF]
Epicyclic gear transmissions which transmit output at a gear ratio dependent only upon the input's direction are considered. A transmission housing envelops two epicyclic gear assemblies, and has shafts extending from it.
Lafever, A. E.
core +1 more source
Performance Indicators Definition during Hydromechanical Transmission Gear Shift
The microprocessor controller deviсе and mathematical model for control were presented. The performance indicators of mobile machines hydro mechanical transmission are shown to determine during shift road testing or modeling experimental period.
V.N. Basalaev +4 more
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Integrated Thermal and Dynamic Analysis of Dry Automotive Clutch Linings
Optimum operation of clutch systems is dictated by their dynamic as well as thermal performance. Both of these aspects are closely related to the interfacial frictional characteristics of the clutch lining material, which also affects the noise ...
Theofilos Gkinis +2 more
doaj +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Evolution of sociality in Anelosimus Spiders [PDF]
Most spiders are solitary and aggressive towards cohorts, but some have been found to live in groups and forage communally, even sharing in brood care. The benefits of group living outweigh the costs of inbreeding for these spiders, but how sociality has
Cotter, Adelaide Speedie
core +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source

