Results 101 to 110 of about 6,180 (208)

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Analysis and design of SOI MEMS step up voltage converters

, 2013
Energy harvesting systems are becoming an increasingly popular area for research as they present themselves as a clean, renewable source of energy. There are currently some key design issues facing the development of these energy harvesting systems.
Gleeson, Rachel
core  

Flip-chip distributed MEMS transmission lines (DMTLs) for biosensing applications

, 2008
Design and characterization of a flip-chip distributed MEMS transmission line (DMTL) are presented. The concept of using this DMTL as a biosensor is then introduced. Radio frequency experiments on the DMTL loaded with biosamples have been conducted using
Uttamchandani, D.G., Li, Lijie, Uttamchandani, Deepak, Lijie Li, Li, L.   +4 more
core   +1 more source

Uncooled, broadband terahertz bolometers using SOI MEMS beam resonators with piezoresistive readout

Microsystems & Nanoengineering
Terahertz (THz) detectors using MEMS resonators have attracted great interests owing to their high sensitivity, rapid response, and room-temperature operation capability.
Ya Zhang, Kazuki Ebata, Mirai Iimori, Qian Liu, Zihao Zhao, Ryotaro Takeuchi, Hua Li, Kazusuke Maenaka, Kazuhiko Hirakawa   +8 more
doaj   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, Volume 13, Issue 32, 9 June 2026.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

A capacitive CMOS–MEMS sensor designed by multi-physics simulation for integrated CMOS–MEMS technology

Japanese Journal of Applied Physics, 2014
This paper reports the design and evaluation results of a capacitive CMOS–MEMS sensor that consists of the proposed sensor circuit and a capacitive MEMS device implemented on the circuit. To design a capacitive CMOS–MEMS sensor, a multi-physics simulation of the electromechanical behavior of both the MEMS structure and the sensing LSI was carried out ...
Toshifumi Konishi, Daisuke Yamane, Takaaki Matsushima, Kazuya Masu, Katsuyuki Machida, Hiroshi Toshiyoshi   +5 more
openaire   +2 more sources

A 164-dBΩ Transimpedance Amplifier for Monolithic CMOS-MEMS Oscillators in Biosensing Applications

IEEE Access
This article presents a fully differential tunable high-gain transimpedance amplifier (TIA) conceived as a front-end circuit for monolithic CMOS-MEMS resonators operating in self-sustained oscillation mode.
Rafel Perello-Roig, Salvador Barcelo, Jaume Verd, Sebastia Bota, Jaume Segura   +4 more
doaj   +1 more source

Memristive Physical Reservoir Computing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Memristors’ nonlinear dynamics and input‐dependent memory effects make them ideal candidates for high‐performance physical reservoir computing (RC). Based on their conductance modulation, memristors can be classified as electronic or optoelectronic types.
Dian Jiao, Ziyuan Wang, Jingrui Wang, Li Zhang, Xianhua Wei, Lingxiang Hu, Zongxiao Li, Athanasios V. Vasilakos, Zhizhen Ye, Fei Zhuge   +9 more
wiley   +1 more source

Design and fabrication of RF MEMS switch by CMOS process

, 2011
This work investigates the fabrication of a RF (ratio frequency) MEMS (micro elector mechanical system) switch using the standard 0.35 μm 2P4M (double polysilicon four metal) CMOS (complementary metal oxide semiconductor) process and the post-process ...
Wu, C.C.
core   +1 more source

Progress in Strain Engineering of 2D‐Integrated Heterostructures for Ultrasensitive Sensors

Advanced Science, Volume 13, Issue 33, 15 June 2026.
 . ABSTRACT Two‐dimensional (2D) integrated heterostructures have emerged as a cornerstone in the advancement of next‐generation sensor technologies. These heterostructures, which combine materials with different dimensionalities, have led to significant breakthroughs in sensing performance and device integration.
That Buu Ton, Tuan Sang Tran, Duc Khanh Tran, Van Thanh Dau, Dzung Viet Dao   +4 more
wiley   +1 more source