CPEB3 Maintains Developmental Competence of the Oocyte [PDF]
Mammalian oocyte development depends on the temporally controlled translation of maternal transcripts, particularly in the coordination of meiotic and early embryonic development when transcription has ceased.
Aleshkina, Daria +9 more
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From gene lists to interaction networks for biological interpretation - Reinterpretation of the results from a diet intervention study in light of a new statistical analysis [PDF]
, 2017 The results of a diet intervention study aiming to enlighten dietary carbohydrates role in proinflammatory responses have been reviewed in light of a new statistical analyses conducted on the microarray data.
Svanem, Maren
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Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach [PDF]
Protein & Cell, 2015 Bai, Yuwei +8 more
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The CNOT complex contributes to the maintenance of genome stability [PDF]
, 2020 The yeast CCR4-NOT (CNOT in mammals) complex is a large (1.0-MDa) and highly conserved multifunctional set of proteins. It is involved in many different aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA ...
Chalabi Hagkarim, Nafiseh
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Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. [PDF]
, 2011 Ruolo del sistema ubiquitina-proteasoma (UPS) nella disfunzione beta cellulare del diabete di tipo 2 e possibili opzioni terapeutiche. Sebbene la disfunzione beta cellulare rivesta un ruolo di primaria importanza nel diabete di tipo 2, le informazioni ad
BUGLIANI, MARCO
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Ένζυμα μεταβολισμού RNA ως μοριακοί δείκτες καρκίνου [PDF]
, 2011 Τοτόμη, Αθηνά Γ.
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The Role of the CNOT3 Subunit of the CCR4-NOT Complex in Cellular Senescence [PDF]
Okinawa Institute of Science and Technology Graduate UniversityDoctor of PhilosophyCellular senescence is a fundamentally irreversible cell cycle arrest associated with upregulated inflammatory responses.
Maipas, Aisulu
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Μελέτες στη βιολογική σημασία της ανθρώπινης αποαδενυλάσης CNOT7
, 2010 Η ακριβής γονιδιακή έκφραση απαιτεί συνεχή έλεγχο των επιπέδων του mRNA. Η αποικοδόμηση του mRNA αποτελεί ρυθμιστικό στοιχείο της γονίδιακής έκφρασης. Στα κύτταρα των θηλαστικών το κύριο μονοπάτι αποικοδόμησης ξεκινά με αποαδενυλίωση, την αφαίρεση δηλαδή των πολύ(Α) ουρών από το 3' άκρο ενός ώριμου mRNA.
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Pharmacogenomics and Personalized MedicineFengxing Huang,1,2,* Youwei Wang,1,2,* Yu Shao,1,2,* Runan Zhang,1,2 Mengting Li,1,2 Lan Liu,1,2,* Qiu Zhao1,2,* 1Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People’s Republic of China; 2Hubei
Huang F +6 more
doaj
CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex
CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT ComplexThe CCR4-NOT deadenylase complex is a major post-transcriptional regulator of eukaryotic gene expression. CNOT7 and CNOT8 are both vertebrate homologs of the yeast CCR4-NOT catalytic subunit Caf1. They are highly similar and are sometimes considered redundant, but Cnot7 and Cnot8 knockout mice exhibit different phenotypes, implying distinct ...
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