Results 71 to 80 of about 89,184 (144)

hnRNP C 및 CNOT7 상호 작용을 통한 Bcl-XL mRNA 안정성 하향 조절로 인한 BTG2의 암세포 사멸 촉진

, 2018
BTG2, as a founding member of anti-proliferative gene family, has been reported to render cancer cells more sensitive to chemotherapy and radiotherapy. Recent study suggested that BTG2 can activate general mRNA deadenylation and degradation as a binding ...
최, 용원
core   +1 more source

Expression levels of miR-466e-3p target genes.

, 2014
Expression levels of Zfp704, Cnot7 and Cplx2, relative to control, were measured by quantitative real-time PCR. Results are the average of three independent experiments. Error bars represent standard deviation.
Hiroko Ishii-Ohba (623275), Guillaume Vares (471320), Tetsuo Nakajima (471322), Bing Wang (126120), Mitsuru Nenoi (471323)   +4 more
core   +1 more source

Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker

, 2012
Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by deadenylases.
Karangeli, M., Papaspyrou, K., Labrou, M., Pournaras, S., Dimoulou, G., Matsouka, P., Gourgoulianis, K. I., Salataj, E., Balatsos, N. A. A., Maragozidis, P.   +9 more
core   +1 more source

A comparison of the crystal structure of S. pombe Caf1p/Pop2p (gray, PDB ID: 2P51) and the predicted structure of CrCaf1 (red).

, 2013
The homology modeling of CrCaf1 structure was performed by SWISS-MODEL using the crystal structure of human Caf1a/CNOT7 (PDB ID: 2D5R) as the template structure. N and C are the N- and C-termini of the proteins.
Yong-Bin Yan (295926), Jia-Quan Zhang (435852), Guang-Jun He (329060)   +2 more
core   +1 more source

M2 Macrophage Classification of Colorectal Cancer Reveals Intrinsic Connections with Metabolism Reprogramming and Clinical Characteristics

Pharmacogenomics and Personalized Medicine
Fengxing Huang,1,2,* Youwei Wang,1,2,* Yu Shao,1,2,* Runan Zhang,1,2 Mengting Li,1,2 Lan Liu,1,2,* Qiu Zhao1,2,* 1Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, People’s Republic of China; 2Hubei
Huang F, Wang Y, Shao Y, Zhang R, Li M, Liu L, Zhao Q   +6 more
doaj  

Regulation of mRNA poly(A) tail length governs mammalian body plan formation in gastruloids. [PDF]

Nat Commun
Taborsky D, Valdivia-Francia F, Serrano P, Muzumdar S, Ranjbar N, Llop-Grau L, Tellez G, Gjonlleshaj P, Duré C, Renz PF, Weber R, Yigit M, Ghoshdastider U, Mironov A, Hyams K, Vianello S, Zavolan M, Bar-Nur O, Lutolf MP, Sendoel A.   +19 more
europepmc   +1 more source

Systematic Evaluation of Different Ribonucleoprotein Complexes as Posttranscriptional Biosensors in Cell-Free TX-TL Systems. [PDF]

ACS Synth Biol
Boyvat D, Grassi F, Cassella L, Siciliano V.   +3 more
europepmc   +1 more source

Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach [PDF]

In eukaryotic cells, the degradation of the mRNA poly(A) tail (deadenylation) is a crucial step in the regulation of gene expression. The Ccr4-Not complex is the major deadenylase enzyme involved in the mRNA deadenylation.
Balacco, Dario Leonardo
core   +2 more sources

Enhancing mRNA stability and translational potential through tailored modifications at the 3' end. [PDF]

RSC Chem Biol
Perzanowska O, Kowalska J, Jemielity J.
europepmc   +1 more source

Complete genome sequence of a tetracycline-resistant bacterium, <i>Variovorax endophyticus</i> HR3-A, isolated from riverine water in Japan. [PDF]

Microbiol Resour Announc
Hayakawa M, Shoda T, Nishizawa T.
europepmc   +1 more source