Results 261 to 270 of about 267,333 (302)

Improving physicochemical properties and pharmacological activities of ternary co-amorphous systems

European Journal of Pharmaceutics and Biopharmaceutics, 2022
The formation of co-amorphous by combining low molecular weight compounds with drugs is a relatively new technology in the pharmaceutical field, which can significantly improve the solubility, dissolution, and stability of poorly water-soluble drugs. However, in our previous studies, the binary co-amorphous system of andrographolide-oxymatrine (AP-OMT)
Xiaoping Fang   +5 more
openaire   +4 more sources

Co amorphous systems: A product development perspective

International Journal of Pharmaceutics, 2016
Solubility is one of the major problems associated with most of the new chemical entities that can be reasonably addressed by drug amorphization. However, being a high-energy form, it usually tends to re-crystallize, necessitating new formulation strategies to stabilize amorphous drugs.
Rahul B, Chavan   +3 more
openaire   +4 more sources

Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

Molecular Pharmaceutics, 2019
The formation of co-amorphous and co-crystal systems are attractive formulation strategies for poorly water-soluble drugs. Intermolecular interactions between the drug and the coformer(s) play an important role in the formation of both systems, making the investigation of transformations between the two systems specifically interesting. The aim of this
Wenqi Wu   +4 more
openaire   +5 more sources

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