Results 281 to 290 of about 267,333 (302)

Long-Term Stabilized and Highly Soluble Bezafibrate-Gliclazide Co-Amorphous Binary System

AAPS PharmSciTech
Metabolic syndrome (MS) has a high prevalence, with an estimated one-quarter of the world population affected by this pathological condition. Among the diseases of this syndrome are dysregulation of lipids, hypertension, and insulin resistance. Unfortunately, available drugs in the market used for treating MS, as almost 75% of all drugs, are highly ...
Jorge Cruz-Angeles, Luz María Martínez, Alice M López López, Paulina Cabada-Aguirre, Marcelo Videa, Alejandra Flores   +5 more
openaire   +2 more sources

Unlocking the potential of flavonoid-based co-crystal and co-amorphous systems

Drug Discovery Today
Flavonoids are polyphenolic compounds that have multiple benefits in treating various life-threatening diseases. Despite their diverse pharmacological activities, the market potential of flavonoids is hampered due to their poor solubility and low bioavailability after oral administration.
Khushi Rode, Indrani Maji, Srushti Mahajan, Pankaj Kumar Singh   +3 more
openaire   +2 more sources

Norfloxacin co-amorphous salt systems: Effects of molecular descriptors on the formation and physical stability of co-amorphous systems

Chemical Engineering Science, 2022
Yuehua Deng, Wenhao Deng, Wenquan Huang, Zhiyong Zheng, Rui Zhang, Shiyuan Liu, Yanbin Jiang   +6 more
openaire   +1 more source

Enhanced dissolution of valsartan-vanillin binary co-amorphous system loaded in mesoporous silica particles

Journal of Microencapsulation, 2019
The study was aimed to prepare a co-amorphous system of valsartan (VAL) with vanillin (VAN) for improving its solubility and dissolution followed by its confinement in mesoporous silica particles (MSPs) to stabilise the co-amorphous system and prevent its recrystallization.
Khan, Hashim Ali, Muhammad, Mohsin Ansari, Fawad, Ali Shah, Fakhar, Ud Din, Muhammad, Abdul Basit, Jin-Ki, Kim, Alam, Zeb   +6 more
openaire   +2 more sources

Investigation of the dissolution rate and oral bioavailability of atenolol-irbesartan co-amorphous systems

International Journal of Pharmaceutics
Irbesartan (IBS), a common drug to treat hypertension, has poor oral bioavailability because of its limited aqueous solubility. Recently, co-amorphous systems (CAMs) have demonstrated the ability to improve the solubility of poorly water-soluble drugs.
Jiaqi, Song, Rui, Bao, Meiqi, Lin, Wen, Li, Peixu, Zhao, Xiaohong, Liu, Qiang, Fu   +6 more
openaire   +2 more sources

Recent Progress of Amorphous Nanomaterials

Chemical Reviews, 2023
Jianxin Kang, Limin Liu, Lin Guo
exaly  

Co-Amorphous System (Paracetamol:Indomethacin): Investigations on Physical Stability and Intermolecular Interactions

Pharmaceutical Chemistry Journal, 2023
Marouene Bejaoui, Rihem Djemi, Salah Kouass, Haykel Galai   +3 more
openaire   +1 more source

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

Nature Reviews Materials, 2020
Jonas G Croissant, Kimberly S Butler, Jeffrey I Zink   +2 more
exaly  

Construction of amorphous/crystalline heterointerfaces for enhanced electrochemical processes

EScience, 2023
Bin-Bin Jia, Lin Chang
exaly  

Amorphous systems for delivery of nutraceuticals: challenges opportunities

Critical Reviews in Food Science and Nutrition, 2022
Pankaj Singh, Jitender Madan, Kamal Dua
exaly